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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin
Ade Fernandes
Department of Dermatology and venereology, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Teaching Hospital Surabaya
Immunology & microbiology Public Health

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The Analysis of Serum Vitamin D (25[OH]D) Level in Psoriasis Patients Comparing with Control Subjects Ade Fernandes; Muhammad Yulianto Listiawan; Evy Ervianti; Trisniartami Setyaningrum
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 2 (2020): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.2.2020.111-118

Abstract

Background: Vitamin D has been shown to have an immunomodulatory effect, and previous studies have proven that vitamin D deficiency contributed to several autoimmune diseases, including psoriasis. Purpose: The purpose of this study was to determine serum vitamin D levels in psoriasis vulgaris patients and compare them with control subjects. Methods: The research samples were sixteen adults with psoriasis vulgaris and 16 control subjects. Blood samples were taken, and the serum 25 (OH) D levels were measured using the Chemiluminescent Microparticle Immunoassay method. Result: The mean serum vitamin D in psoriasis vulgaris patients and controls were 14.36 ± 6.36 and 19.92 ± 7.59 ng/mL, respectively. No psoriasis vulgaris were observed in patients with normal 25(OH)D levels, and only 3 control subjects with normal serum 25(OH)D levels. These results were not statistically significant (p = 0.09). Conclusion: Most patients with psoriasis vulgaris were observed having vitamin D deficiency. However, the prevalence of vitamin D deficiency in the control subjects was high as well. Therefore, there were no differences in serum 25(OH)D levels between psoriasis vulgaris and control patients.
Co-Authors Evy Ervianti M. Yulianto Listiawan Trisniartami Setyaningrum