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All Journal Folia Medica Indonesiana PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)
Khairil Armal
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INJECTED CITICOLINE IMPROVES IMPAIRMENT AND DISABILITY DURING ACUTE PHASE TREATMENT IN ISCHEMIC STROKE PATIENTS Rino Wahyudi; Didik Hasmono; Ruhaya Fitrina; Khairil Armal
Folia Medica Indonesiana Vol. 51 No. 4 (2015): Oktober - December 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.922 KB) | DOI: 10.20473/fmi.v51i4.2854

Abstract

Treatment strategy of ischemic stroke is to reduce the extent of the damage and rescue neurons from death in the early days of ischemic events. Recombinant Tissue-Plasminogen Activator (r-TPA) is the only recommended therapy, but their use is very limited. Citicoline is a neuroprotectant with a therapeutic effect on several stages of the ischemic cascade. However, its use is still being debated. The purpose of this study was to analyze the use of supplementation citicoline injection in patients with acute ischemic stroke in relations to differences in changes in the level of interference (impairment), rate limitation (disability) and the level of obstruction (handicap) between the group receiving supplementation of citicoline injection 2x500 mg iv and the group without supplementation during acute phase treatment. This study was a prospective cohort study using experimental design in patients with acute ischemic stroke who met the inclusion and exclusion criteria with or without supplementation citicoline between January - April 2015 in the National Stroke Hospital, Bukittinggi. Rate of interference was assessed with NIHSS, level of limitations with Barthel Index, and level of obstruction with modified Rankin Scale. Assessment was done 2 times, before and after the treatment. Statistical methods used in this study were Wilcoxon signed rank test, paired T-test and Mann-Whitney test. This study was conducted on 50 subjects divided into 2 groups, a control group without supplementation and group treated with injected citicoline of 2x500 mg iv. Demographic and baseline characteristics did not differ between groups. There were differences in level of interference changes. Mean decrease in control group was 0.96 ± 1.74 NIHSS, while that in treatment group was 2.84 ± 1.46 NIHSS (p <0.05). There were differences in changes in the level of limitations. Mean increase of Barthel Index in control group 9.60 ± 11.17 and in treatment group 20.40 ± 13.99 (p <0.05). However, changes in the level obstacle showed no difference. In conclusion, citicoline injection supplementation in patients with ischemic stroke during acute phase treatment showed improvement differences in changes in the level of distraction (impairment) and the rate limitations (disability), but showed no difference in changes in the level of obstruction (handycaps).
ANALISIS PENGARUH PERSEPSI PASIEN TENTANG PELAYANAN FARMASI TERHADAP LOYALITAS PASIEN DI APOTEK RAWAT JALAN RUMAH SAKIT STROKE NASIONAL BUKITTINGGI Amelia Sari; Auzal Halim; Khairil Armal
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 10 No. 01 Juli 2013
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v10i1.775

Abstract

ABSTRAK Persepsi adalah suatu proses individu memilih, mengorganisasi dan menafsirkan informasi untuk menciptakan satu gambaran yang berbeda. Loyalitas dipengaruhi oleh komitmen tinggi, kepercayaan, dan pembelian ulang. Tujuan penelitian adalah melihat pengaruh persepsi pasien tentang pelayanan farmasi terhadap loyalitas pasien di apotek rawat jalan Rumah Sakit Stroke Nasional Bukittinggi. Jenis penelitian ini adalah observational research dengan pendekatan cross sectional. Jumlah responden adalah 100 pasien apotek rawat jalan umum. Data dianalisis secara univariat dan bivariat menggunakan uji Chi Square pada tingkat kesalahan 10%. Hasil penelitian menunjukkan persepsi pasien tentang 6 variabel pelayanan farmasi yaitu penampilan (p value= 0,259), kemudahan layanan (p value= 0,513), ketersedian obat (p value= 0,126), kecepatan layanan (p value= 0,126), kompetensi petugas (p value= 0,272) dan pemberian informasi obat (p value= 0,369) tidak ada hubungan yang bermakna dengan loyalitas pasien. Hanya variabel keramahan petugas (p value = 0,000) yang ada hubungan yang bermakna dengan loyalitas pasien. Kata kunci: persepsi, loyalitas pasien, pelayanan farmasi. ABSTRACT Perception is an individual process of selecting, organizing and interpreting information to create a different picture. Loyalty is influenced by the high commitment, trust and repeat purchase. The research objective look at the influence of the patient's perception of pharmacy services to the loyalty of patients in outpatient pharmacy of National Stroke Hospital in Bukittinggi. The study was observational research with cross sectional approach. The number of respondents was 100 patient general outpatient pharmacy. Data were analyzed using univariate and bivariate Chi Square test at an error rate of 10%. Results showed patient’s perceptions about 6 variables pharmacy services, namely appearance (p value = 0.259), ease of service (p value = 0.513), availability of drugs (p value = 0.126), speed of service (p value = 0.126), competence of personnel (p value = 0.272) and the provision of drug information (p value = 0.369) there was no significant correlation with patient loyalty. Only variables hospitality workers (p value = 0.000) that there is a significant association with patient loyalty. Key words: perception, patient loyalty, pharmacy services.
Co-Authors Amelia Sari Auzal Halim Didik Hasmono Rino Wahyudi Ruhaya Fitrina