Sri Mardjiati Mei Wulan
Department Of Physical Medicine And Rehabilitation Faculty Of Medicine, University Of Airlangga, Dr. Soetomo General Hospital, Surabaya, Indonesia.

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Physical Exercise in Clinical Stage IIhuman Immunodeficiency Virus Infection Patients’ Increasesskeletal Muscle MAss Through the Increasing of Myogenic Regulatory Factors Expression Sri Mardjiati Mei Wulan; Hening Laswati; Usman Hadi; Nasronudin Nasronudin
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17091


Background: Human Immunodeficiency Virus infection is a chronic diseasethat threatensthe health ofmillionsof people inthe worldand causing disability. One of the factors that causedisabilityis HIVmusclewasting,causing a decrease inthe quality of lifethat interferethe daily activitiesand evenincreased mortality. Properphysical exercise is needed to prevent and treat muscle wasting.Methods: This studyusinghuman subjectswithclinicalstageII HIVinfection. Subjectswere groupedinto two:Intervention (n =9) that subjects whogetmoderate-intensity physicalexercise (HIVA) for 8weeks andControl (n=9) as subjects wereobservedfor 8 weeks. Muscles samples were taken fromthe vastuslateralismusclebiopsiesthat performed24 hoursafterthe lastphysical exercise,immunohistochemicalexaminationwithmonoclonalantibodyanti-Pax7, anti-MyoD1 andanti-myogenin and measurement of thigh circumference.Results: Therewere significant increase in regeneration of skeletal muscle in the intervention group(increasing of Pax7, MyoD1 and myogenin) than the control groupand significant increase in quadricepsmuscles mass as measured by thigh circumference (p < 0.001).Conclusion: HIVA physical exerciseof moderate intensityincreasesskeletal muscleregenerationinclinicalstageII HIVinfectionthroughthe increasingPax7, MyoD1, myogeninexpression and followed by an increaseof quadriceps muscles mass.
Cross-Cultural Adaptation of Indonesian Version of Activities-Specific Balance Confidence Scale for Elderly in Surabaya Andi Nuruzzaman; Rwahita Satyawati; Sri Mardjiati Mei Wulan
Folia Medica Indonesiana Vol. 56 No. 4 (2020): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.887 KB) | DOI: 10.20473/fmi.v56i4.24601


Falling is a major health problem and is also a major cause of morbidity and mortality in the elderly. The more serious consequences of falling on the elderly are the increased risk of injury and fear of falling. Activities-Specific Balance Confidence (ABC) scale is one of the assessment instruments for fear of falling. This instrument is used to assess balance confidence in various ambulation activities. The purpose of this study was to carry out the process of adaptation of the cross cultural ABC English questionnaire to ABC Indonesian. This study was a cross sectional study with participants of five elderly members of the Posyandu Lansia who were in accordance with the inclusion and exclusion criteria. The output is the correlation between the score of ABC English with ABC Indonesian and the score of ABC Indonesian with ABC English Back Translation which are tested at different times. All the question score in the ABC English questionnaire correlated with ABC Indonesian, as well as the Indonesian Language ABC correlated with ABC English back translation, have a significant correlation (r> 0.3). The conclusion of this study is that the ABC English has a close meaning with the ABC Indonesian and the ABC Indonesian has a close meaning with the ABC English back translation. The validity and reliability of the Indonesian version of ABC questionnaire is needed to obtain a valid and reliable questionnaire.
Effect of Power-Assisted Functional Electrical Stimulation (PAFES) and Occupational Exercise on Motor Unit Activity of Extensor Digitorum Communis and Hand Dexterity in Post-stroke Patient Yusuf Roni; Sri Mardjiati Mei Wulan; I Putu Alit Pawana
Surabaya Physical Medicine and Rehabilitation Journal Vol. 2 No. 2 (2020): SPMRJ, AGUSTUS 2020
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v2i2.17602


Background: Weakness of upper extremity can affect the ability to perform daily activities in post-stroke patients. Power-Assisted Functional Electrical Stimulation (PAFES) may give motor reeducation and sensory feedback to improve motor recovery through neuroplasticity.Aim: To evaluate the effect of PAFES and occupational exercise on post-stroke patient hand dexterity and motor unit activity of extensor digitorum communis muscle.Material and methods: Twenty post-stroke patients enrolled in the study were divided intervention group whom received PAFES and occupational exercise, and control group whom received occupational exercise only. Each group underwent 30 minutes per session of treatment, 5 times a week, for 3 weeks. The Root Mean Square (RMS) for measuring motor unit activity of extensor digitorum communis muscle; Box and Block Test (BBT) and Nine Hole Peg Test (NHPT) for measuring hand dexterity were evaluated before and after intervention.Result: There were significant improvements of RMS (p<0.001), BBT (p<0.001) and NHPT (p=0.002) in intervention group after receiving PAFES and occupational exercise. The improvement of BBT in intervention group was significant compared with control group (p=0.028), however, no significant improvement of NHPT was found between groups.Conclusion: PAFES and occupational exercise could improve motor unit activity of the extensor digitorum communis muscle and hand dexterity in post-stroke patient.