Article Per Year (5 Year)
p-Index From 2019 - 2024
0
P-Index
This Author published in this journals
All Journal Medical Journal of Indonesia Indonesian Journal of Cancer Chemoprevention
Jeanne A. Pawitan
Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Published : 28 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 28 Documents
Search

 1   2   3 
Genetic factors associated with susceptibility to obesity Pawitan, Jeanne A.
Medical Journal of Indonesia Vol 8, No 4 (1999): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (876.13 KB) | DOI: 10.13181/mji.v8i4.715

Abstract

[no abstract available]
The micronucleus test: A method used in mutagenicity testing Pawitan, Jeanne A.
Medical Journal of Indonesia Vol 4, No 2 (1995): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (840.799 KB) | DOI: 10.13181/mji.v4i2.893

Abstract

[no abstract available]
Application of Feulgen-light green staining method to show the micronuclei in fetal rat blood Pawitan, Jeanne A.; Tanzil, Robertus
Medical Journal of Indonesia Vol 4, No 4 (1995): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.909 KB) | DOI: 10.13181/mji.v4i4.928

Abstract

[no abstract available]
Secretion of Indoleamine 2,3-Dioxygenase, an Immunomodulatory Substance, by Adipose-Derived Mesenchymal Stem Cell Laksmitawati, Dian R; Sardjono, Caroline Tan; Pawitan, Jeanne A.; Sadikin, Mohammad; Sandra, Ferry
Indonesian Journal of Cancer Chemoprevention Vol 1, No 2 (2010)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4.399 KB)

Abstract

Lipoaspirate, a wasted by product from liposuction procedure recently has been shown to contain abundant adipose-derived-mesenchymal stem cells (MSCs). Mesenchymal stem cells (MSCs) have been studied in many research areas to regenerate many cell lineages. In addition, MSCs have immunomodulatory effect. This capability has been utilized in several clinical studies in hematopoetic stem cell and organ transplantation as a strategy to reduce the risk of Graft versus Host Disease (GvHD). It has been reported that the ‘stimulated’ MSC is able to secrete substances to suppress tissue rejection. One of the substances was known to be indoleamine 2,3-dioxygenase (IDO).  A previous study has  characterized the secretion of IDO by bone marrow-derived MSCs stimulated by an inflammatory mediator interferon gamma (IFN-γ). IDO has been detected using Western blot analysis and by High Performance Liquid Chromatography (HPLC) assay. The aim of this study was to detect the presence of IDO in AD-MSCs culture with and without INFγ stimulation. Our study showed that AD-MSC stimulated with IFN-γ significantly secreted high level of IDO as detected by Enzyme-Linked Immuno Sorbent Assay (ELISA). Despite its property as a proinflammatory mediator, IFN-γ has shown to be able to induce IDO secretion in MSC culture which suggests the immuno modulatory effect of MSC. This study clearly demonstrates the potential application of adipose-derived MSC in the immunomodulatory strategy for allogenic transplantation.  
Language barrier, funding, communication and time management problems found in the Medical Journal of Indonesia, 1995 - 2001 Suryono, Isnani A.; Pawitan, Jeanne A.; Saifuddin, Abdul B.
Medical Journal of Indonesia Vol 10, No 4 (2001): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (802.413 KB) | DOI: 10.13181/mji.v10i4.41

Abstract

The objective of this study is to assess the problems encountered in the management of Medical Journal of Indonesia and whether any progress has been achieved during the past 7 years. A retrospective descriptive study was done in the MJI. Available data used as parameters were: number of articles submitted and authors home institution, number of articles submitted and rejected, cause/criteria of rejection, qualification of reviewers and editors, duration of manuscript processing, and whether pre-scheduled time is met in the Med J Indones. For this purpose, all manuscripts from January 1995- January 2001 were evaluated. In addition, recent problems encountered were noted. Problems encountered were limited supply of manuscript that might be due to language barrier, decrease in circulation due to limited budget, communication problems due to seniority, and increase in average processing time that might be due to restriction in the time allocated for MJI Number of articles submitted by authors originating from national versus foreign institutions in 1995-1997 was 101 versus 16, and in 1998 - 2000 were 124 versus 84. Articles rejected were ±26.4 % (1999-2001) and the most frequent causes of rejection were insignificancy of substance and improper data analysis. As for the qualification of editors there was an increase in the number of PhDs and professors. Average processing time is approximately 1.5 times the scheduled time. It seems that the 4 main problems encountered were (1) Language barrier, (2) Funding, (3) Communication problems and (4) Time management; and though not impressive, there are definitely positive changes in the number of manuscipts submitted, qualification of editors and peer reviewers. Average processing time is about the same, and the prescheduled time of editing is yet to be met. (Med J  Indones 2001; 10: 252-8)Keywords: language barrier, funding, communication problems, time management
The possible role of nutritional intervention to prevent diabetic retinopathy Pawitan, Jeanne A.
Medical Journal of Indonesia Vol 17, No 4 (2008): October-December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.09 KB) | DOI: 10.13181/mji.v17i4.562

Abstract

[No Abstract Available]
Phytoestrogens beneficial effects on cardiovascular system Pawitan, Jeanne A.
Medical Journal of Indonesia Vol 11, No 2 (2002): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (461.967 KB) | DOI: 10.13181/mji.v11i2.60

Abstract

Several lines of evidence, including epidemiological, clinical trial and basic science, suggest the plausability of a causal, inverse relationship between phytoestrogens and cardiovascular disease. Phytoestrogens are naturally occurring plant compounds that have 2-phenylnaphthalene-type chemical structures similar to those of estrogens. they are simply divided into three main classes, isoflavones, lignans, and coumestans. The majority of phytoestrogens found in typical human diets are the isoflavones and lignans. This review provides an overview of the potential sources and bio-availability of the phytoestrogens particularly isoflavones, and discusses their beneficial effects on cardiovascular system, i.e. on atherosclerosis, hypercholestrolemia, arterial compliance, and blood pressure. (Med J Indones 2002; 11: 120-3)Keywords: atherosclerosis, hypercholestrolemia, arterial compliance, blood pressure
Comparison of various procedures in the processing of binucleated-lymphocytes on to glass slide to detect chromosomal breakage Pawitan, Jeanne A.; Suryono, Isnani A.; Damayanti, Lia; Purbadi, Sigit
Medical Journal of Indonesia Vol 12, No 1 (2003): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (177.322 KB) | DOI: 10.13181/mji.v12i1.83

Abstract

Binucleated lymphocytes can be screened for micronuclei to assess chromosomal damage. There are various procedures to get slides containing binucleated lymphocytes, that are different in harvesting, fixation, and slide preparation methods. Screening binucleated lymphocytes to find a micronucleus needs at least 800 cells with intact cytoplasm. This study aimed to analyze the various procedures and simplified procedures to know which procedure gave the most abundant binucleated lymphocytes with intact cytoplasm and best staining properties for the purpose of micronucleus scoring. Seven heparinized blood samples were obtained from the Dept. of Obstetrics and gynecology, Faculty of medicine, University of Indonesia, Jakarta. The 7 blood samples were subjected to 17 procedures different in harvesting (with or without washing), slide preparation (smear and spot method, and using a cytocentrifuge), and fixation methods (methanol for 1 minute, methanol brief, methanol/glacial acetic acid 3:1 or 9:1). Our results showed that fixatives containing glacial acetic acid are not suitable for micronucleus test. To generate binucleated lymphocytes with intact cytoplasm as much as possible, the procedure should be conducted without washing steps. Methanol fixation either briefly or 1 minute is preferable, and for the ease of screening cytocentrifuge preparation, followed by spot method is preferable. (Med J Indones 2003; 12: 3-7) Keywords: cytokinesis blocked, spot, smear, cytocentrifuge, fixatives
Association between presence in lectures and student knowledge gain in problem based learning: experience in Neuropsychiatry module, FMUI, International Program Pawitan, Jeanne A.; Sukmawati, Dewi
Medical Journal of Indonesia Vol 18, No 2 (2009): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.85 KB) | DOI: 10.13181/mji.v18i2.353

Abstract

Aim This study was conducted to determine the association between presence in lecture and examination scores.Methods This was a cross sectional study, conducted in the Faculty of Medicine University of Indonesia, International Class Program, from November 2007 to May 2008. The subject’s inclusion criterion was FMUI International class students enrolled in the Neuropsychiatry module in 2007/2008. we excluded students who did not attend the examinations i.e. multiple choice questions (MCQ)-1, -2, or essay. The data collected were presence in lecture and examination scores. Data analysis was done using SPSS linear regression to see the association between presence in lectures and exam scores.Results The results showed that the R and P of the association between presence in lectures and exam scores were (R= 0.121, P= 0.413), (R= 0.212, P= 0.148), (R= 0.260, P= 0.075), and (R= 0.280, P= 0.054) for MCQ1, MCQ2, essay, and mean exam scores respectively.Conclusion We failed to show the association between presence in lectures and student knowledge gain. This result might be due to the many factors discussed that were not analyzed in this study. (Med J Indones 2008; 18: 131-4)Key words: exam, MCQ, essay
Stem cells and the prospect of tissue engineering Pawitan, Jeanne A.
Medical Journal of Indonesia Vol 18, No 2 (2009): April-June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (182.437 KB) | DOI: 10.13181/mji.v18i2.559

Abstract

[No Abstract Available]
Co-Authors Abdul B. Saifuddin Ahmad R. Utomo Alam R. Kusnadi, Alam R. Arleni Arleni Arleni Bustami Caroline T. Sardjono Caroline Tan Sardjono Des Suryani Dewi Sukmawati Dian R Laksmitawati Dian R. Laksmitawati Ferry Sandra Harahap, Alida R. Isabella K. Liem Isnani A. Suryono Jinia Lilianty Kartolo, Wiwi A. Lia Damayanti Mohamad Sadikin Mohammad Sadikin Ni M. Swantari Radiana D. Antarianto Rahyussalim Rahyussalim, Rahyussalim Retno W. Susilowati Reza Y. Purwoko Robertus Tanzil Septelia I. Wanandi Sigit Purbadi Tri Kurniawati, Tri Twidy Tarcisia, Twidy Yefta Moenadjat