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Kajian Peran Gen P53 dalam Tumorigenesis Retina Yunani
VITEK : Bidang Kedokteran Hewan Vol 6 (2016): VITEK - Bidang Kedokteran Hewan
Publisher : Fakultas Kedokteran Hewan Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jv.v6i0.27

Abstract

Gene p53 is a tumor suppressor gene that in normal conditions is in ' standby ' mode , several studies show that pivotal point that lead to stimulation of p53 is DNA damage , heat shock , hypoxia, exposure of nitric oxide ( NO ) , the expression of oncogenes and some p53 pathways activation. p53 mechanism as a guardian of genome stability are cell cycle arrest, repair of DNA damaged, induce apoptosis, prevents angiogenesis , invasion and metastasis ability of the tumor. On many tumor , p53 is not loss , but mutated , the p53 mutant was expressed 70 % in lung cancer , and in different frequencies in other cancers . Then the role of p53 as a transcription factor that works to regulate genes involved in tumor suppression is indispensable .
PEMANFAATAN INFUSA DAUN SIRIH MERAH (Piper crocatum) SEBAGAI ANTI-OBESITAS PADA MENCIT (Mus musculus) Desty Apritya; Miarsono Sigit; Retina Yunani; Fuji Lestari
VITEK : Bidang Kedokteran Hewan Vol 10 (2020): VITEK - Bidang Kedokteran Hewan
Publisher : Fakultas Kedokteran Hewan Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jv.v10i0.49

Abstract

The purpose of this research is to know the effectiveness of red betel leaf infusion (Piper crocatum) as anti-obesity in mice (Mus musculus). Other parameters of this study to know the relationship between changes in blood glucose levels to obesity in experimental animals. Experimental animals used were 24 male mice. The design of this research is completely randomized design (CRD) with 4 treatments 6 repetitions. There are four treatmens P0 (Control), P1 (6 mice by giving a betel leaf infusion with a concentration of 5%), P2 (6 mice by giving a betel leaf infusion with a concentration of 10%), and P3 (6 mice by giving a betel leaf infusion with a concentration of red 15%). The treatment is carried out once every day for 21 days. Before treatment, initial weight was weighed and blood glucose level examination continued on the 7th day, on the 14th day, and on the 21st day. Data obtained from the results of weighing and checking blood sugar levels were further analyzed using the ANOVA test which statistically showed no significant changes (P> 0.05) of body weight and blood glucose levels in mice (Mus musculus) given infusion red betel leaf (Piper crocatum).
Efektivitas salep ekstrak daun sirih merah (Pipercrocatum) terhadap luka insisi pada tikus putih (Rattus norvegicus) Ratna Widyawati; Ferrini Kasy; Retina Yunani; Junianto Wika Adi Pratama
VITEK : Bidang Kedokteran Hewan Vol 11 No 2 (2021): VITEK-Bidang Kedokteran Hewan
Publisher : Fakultas Kedokteran Hewan Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jv.v11i2.82

Abstract

This study aims to see the effectiveness of red betel leaf extract ointment against incision wounds in white rats. The tannin and saponin compounds found in red betel leaf extract function to stimulate the formation of collagen which plays a role in the wound healing process. This study used an experimental research method with the test materials being 21 male white rats (Rattus norvegicus), red betel leaf extract on wound adhesions, the total number of erythrocytes and hemoglobin in white rats due to incision wounds, divided into 3 treatment groups with 7 samples. The results of the mean value of wound attachment in the groups P0 18 ± 0.5, P1 8.5 ± 0.4 and P2 6.5 ± 0.0. The mean results of erythrocyte values in the P0 group were 6.16 ± 0.90a, P1 6.46 ± 0.45a, and P2 6.20 ± 0.63a. and the results of the mean hemoglobin values in the P0 group 11.8 ± 1.1a , P1 12.3 ± 0.7a , and P2 12.1 ± 1.2a . The results of the study showed that the administration of red betel leaf extract ointment (Piper crocatum) on wound attachment had a significant effect at a concentration of 45%, because it was believed that red betel leaf extract ointment could increase peristaltic movements. While the total number of erythrocytes and hemoglobin due to incision wounds in white rats (Rattus norvegicus) there was no significant difference.
PENDAMPINGAN PEMERIKSAAN HEWAN DAN DAGING QURBAN DI MASA PANDEMI COVID-19: Assistance In The Examination Of Animal And Qurban Meat During The Covid-19 Pandemic Freshinta Jellia Wibisono; Lailia Dwi Kusuma Wardhani; Retina Yunani; Adhitya Yoppy Ro Candra; Asih Rahayu; Bagus Uda Palgunadi; Nurul Hidayah; Desty Apritya; Dyah Widhowati; Era Hari Mudji
IGKOJEI: Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2022): IGKOJEI: Jurnal Pengabdian Masyarakat
Publisher : Fakultas Peternakan Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46549/igkojei.v3i1.264

Abstract

Slaughtering of sacrificial animals is a worship activity for slaughtering ruminant livestock which is carried out on Eid al-Adha and carried out in mosques or outside Slaughterhouses (RPH). The limited facilities affect the welfare of the animals so that it affects the quality of the meat. Supervision in the production chain with antemortem and postmortem inspections is carried out to obtain good quality meat. This community service aims to help the community get a guarantee of safe, healthy, whole and halal, sacrificial animal meat with antemortem and postmortem examinations, as well as holding counseling on the handling of sacrificial animals and meat during the covid-19 pandemic through webinars. The activity was carried out in 13 mosques in the areas of Surabaya, Sidoarjo, Gresik, and Pasuruan. The antemortem examination will be held on 19-22 July 2021 followed by a post-mortem examination which will be held on 20-22 July 2021 with a total number of 112 cows, 220 goats and 1 sheep. The Webinar was held earlier, namely on July 14, 2021, by 3 competent speakers. The webinar was attended by the general public, mosque takmir, lecturers, and students. The results of the antemortem examination indicated that the animals were suitable for slaughter, although 2–6 (0.6–1.8%) animals showed diarrhea, nasal and eye discharge, and infection of the prepuce. The results of postmortem examination stated that the animals were fit for consumption with a note that the organs infected with worms had to be removed, namely 15.2% of the liver of cattle and 0.9% of the liver of goats with fasciolosis, 0.5% of goats experiencing parampistomiasis and 1.7% of cattle experiencing eurytrematosis.
PEMERIKSAAN GOLONGAN DARAH DAN TRANSFUSI DARAH PADA KUCING DAN ANJING SECARA GRATIS DI RUMAH SAKIT HEWAN PENDIDIKAN WEKA FAKULTAS KEDOKTERAN HEWAN UNIVERSITAS WIJAYA KUSUMA SURABAYA Era Hari Mudji Restijono; Retina Yunani; Palestin Palestin; Hana Cipka Pramuda Wardhani; Desty Apritya; Kurnia Desiandura; Dian Ayu Kartika Sari; Muhammad Noor Rahman; Ady Kurnianto; Junianto Wika Adi Pratama; Intan Permatasari Hermawan
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 9 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i9.3314-3319

Abstract

Pemeriksaan golongan darah kucing merupakan hal penting sebagai salah satu screening awal jika ingin melakukan transfusi darah pada kucing. Transfusi darah dilakukan pada pasien yang membutuhkan atau dalam keadaan darurat seperti anemia berat, infeksi parasit darah, atau dalam keadaan traumatik yang menyebabkan adanya pendarahan hebat. Transfusi darah dapat meningkatkan prosentase keselamatan pasien yang menderita kejadian tersebut. Pada saat transfusi darah, wajib menyiapkan pendonor dan resipien yang sudah terseleksi dengan ketat, antara lain dalam keadaan sehat, bebas parasit darah, bebas infeksi Feline Immunodeficiency Virus dan Feline Leukimia Virus, dan indoor life.
PENCEGAHAN PENYAKIT CORONA VIRUS PADA KUCING DENGAN METODE RAPID TEST SEBAGAI UPAYA MENDUKUNG PROGRAM ONE HEALTH ANTARA KESEHATAN MANUSIA, HEWAN DAN LINGKUNGAN Intan Permatasari Hermawan; Era Hari Mudji; Palestin Palestin; Retina Yunani
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 6, No 5 (2023): martabe : jurnal pengabdian kepada masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v6i5.1766-1770

Abstract

Tujuan dari program pengabdian kepada masyarakat (PKM) ini antara lain pencegahan penyakit Corona virus pada kucing melalui metode rapid test kit untuk mendeteksi adanya Corona virus dalam mendukung program One health yaitu satu kesatuan antara kesehatan manusia, hewan dan lingkungan. Corona virus merupakan penyakit yang disebabkan oleh virus Feline coronavirus (FCov) yang bisa menyebabkan Feline Infectious Peritonitis, walaupun Coronavirus pada kucing tidak bersifat zoonosis tetapi upaya one health perlu dilakukan untuk mencegah penyebaran penyakit. Metode PKM ini dengan cara observasi melalui signalement, anamnesa dan pemeriksaan fisik kucing kemudian, metode pengambilam sampelnya dengan target 30 ekor kucing baik jantan atau betina dan tidak mengenal usia kucing atau berat kucing. Lokasi pengambilan sampel di Rumah Sakit Hewan Pendidikan UWKS mulai Januari-Februari 2023. Pengambilan sampel swab anus untuk dilakukan pemeriksaan Corona virus dengan rapid kit antigen. Hasil dari rapid kit antigen ditemukan 1 positif coronavirus dari 30 sampel atau sebesar 3,33% yang positif. Harapan dilakukan nya PKM ini adalah mendukung program World Health Organization (WHO) dan Office International des Epizooties (OIE).