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All Journal Paediatrica Indonesiana Majalah Kedokteran Nusantara The Journal Of Medical School
Guslihan Dasa Tjipta
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Health Professions Medicine & Pharmacology

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Oral erythromycin for treatment of gastrointestinal dysmotility in premature infants Armelia Moesri; Bugis Mardina Lubis; Asrul Asrul; Atan Baas Sinuhaji; Guslihan Dasa Tjipta
Paediatrica Indonesiana Vol 47 No 5 (2007): September 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.252 KB) | DOI: 10.14238/pi47.5.2007.234-7

Abstract

Background Functional immaturity of gastrointestinal (GI)motility predisposes preterm infants to feeding intolerance.Erythromycin as a prokinetic agent has been given to preterminfants for the management of non-obstructive GI dysmotility.Objective To evaluate the efficacy of oral erythromycin for thetreatment of GI dysmotility in preterm infants.Methods A randomized controlled clinical trial was done at AdamMalik Hospital and Pirngadi Hospital, Medan, between October2004 – March 2005. Fifty preterm infants with feeding intolerancewere randomly assigned to either receive oral erythromycin (12.5mg/kg, every 6 hours) or placebo for 7 days. Improved tolerancefor enteral feedings was evaluated by the amount of gastric residuebefore feeding.Results On the sixth day, there was a significant difference in theamount of residue from gastric residue between the oralerythromycin group and placebo group (mean 21.7 and 29.4;P<0.05) and so were results on the seventh day (mean 14.1 and26.9; P<0.05).Conclusion Oral erythromycin reduces the amount of gastricresidue before feed in premature infants.
Pengaruh domperidon terhadap produksi ASI pada ibu yang melahirkan bayi premature Tengku Ellya Fazilla; Guslihan Dasa Tjipta; Emil Azlin; Pertin Sianturi
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Mother who gave birth to premature babies often have difficulty getting adequate milk production. Various attempts to increase milk production have been made, including pharmacological interventions. One of the drugs that can be used is domperidone. Domperidone is a peripheral dopamine receptor antagonist, works by blocking the inhibitory effects of dopamine-mediated prolactin secretion, thereby increasing milk production. Three randomized double-blind study showed that domperidon can increase milk production without causing any side effects to the mother and baby.Keywords : domperidone; premature; breastfed
Terapi antibiotika empiris pada neonatus Muchtar Kusuma Hayatullah; Guslihan Dasa Tjipta; Pertin Sianturi; Emil Azlin; Bugis Mardina Lubis; Syamsidah dr; Fera Wahyuni
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Neonatal sepsis is a clinical syndrome with symptoms of systemic infection and followed by bacteremia in the first month of life. Antibotic initial therapy empirically is often given concomittantly awaiting the results of blood cultures in neonates with suspected sepsis. The recommended initial treatment in general is a combination of ampicillin and aminoglycoside (gentamicin). Alternative to aminoglycosides is the third-generation cephalosporins (eg cefotaxime). This regimen was found safe and effective by appropriate duration of therapy. This therapy should be evaluated every 48 hours with a lingering risk of therapy associated with increased risk of necrotizing enterocolitis and death.Keyword : antibotic initial, Neonatal sepsis
Osteopenia prematuritas dan upaya pencegahannya Febriyanti Mobilina; Guslihan Dasa Tjipta; Emil Azlin; Pertin Sianturi; Bugis Mardina Lubis; Beby Syofiani Hasibuan
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 3 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Osteopenia of prematurity is a common problem encountered in preterm infants or infant with low birth weight. This is characterized by decreased bone mineral content due to inadequat nutritional intake and biochemical factors. This condition can make metabolic disorders in pathological bone fractures even in newborns. Incidence of osteopenia in low birth weight infants in 30%, whereas in infants less than 1000 g of about 55%, and infants less than 1500 g as much as 23%. For preterm infants, the features commonly associated with fracture are delivery at less than 28 weeks of gestation. Metabolic bone disease is often not detected at early stage and became known after appearing obvious abnormalities in the bone or in radiologic examination. Therefore, it is necessary to screening with serum biochemical examination of blood in serum levels of calcium, phosphate and alkaline phosphatase. In addition, it was important to intake of calcium and phosphorus are sufficient for bone mineralization. Key word : osteopenia of prematurity, preterm, calcium, calcium
Co-Authors Armelia Moesri Asrul Asrul Atan Baas Sinuhaji Bugis Mardina Lubis Emil Azlin Febriyanti Mobilina Fera Wahyuni Muchtar Kusuma Hayatullah Pertin Sianturi Syamsidah dr Syofiani Hasibuan, Beby Tengku Ellya Fazilla