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Comparison of oxygen saturation measured by pulse oximetry and arterial blood gas analysis in neonates Srie Yanda; Munar Lubis; Yoyoh Yusroh
Paediatrica Indonesiana Vol 43 No 6 (2003): November 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (305.441 KB) | DOI: 10.14238/pi43.6.2003.211-5

Abstract

Background Arterial blood gas is usually beneficial to discern thenature of gas exchange disturbances, the effectiveness of com-pensation, and is required for adequate management. AlthoughPaO 2 is the standard measurement of blood oxygenation, oxygensaturation measured by pulse oximetry (SapO 2 ) is now a custom-ary noninvasive assessment of blood oxygenation in newborn in-fants.Objective To compare oxygen saturation measured by pulse oxi-metry (SapO 2 ) and arterial blood gas (SaO 2 ), its correlation withother variables, and to predict arterial partial pressure of oxygen(PaO 2 ) based on SapO 2 values.Methods A cross sectional study was conducted on all neonatesadmitted to Pediatric Intensive Care Unit (PICU) during February2001 to May 2002. Neonates were excluded if they had impairedperipheral perfusion and/or congenital heart defects. Paired t-testwas used to compare SapO 2 with SaO 2 . Correlation between twoquantitative data was performed using Pearson’s correlation. Re-gression analysis was used to predict PaO 2 based on SapO 2 val-ues.Results Thirty neonates were included in this study. The differ-ence between SaO 2 and SapO 2 was significant . There were sig-nificant positive correlations between heart rate /pulse rate andTCO 2 , HCO 3 ; respiratory rate and TCO 2 , HCO 3 , base excess (BE);core temperature and HCO 3 , BE; surface temperature and pH,TCO 2, HCO 3, BE; SapO 2 and pH, PaO 2 ; and significant negativecorrelation between SapO 2 and PaCO 2 ; the correlations were weak.The linear regression equation to predict PaO 2 based on SapO 2values was PaO 2 = -79.828 + 1.912 SapO 2 .Conclusion Pulse oximetry could not be used in place of arterialblood gas analysis available for clinical purpose
Hemolytic anemia in falciparum and vivax malarial patients based on serum bilirubin examination Yoyoh Yusroh; Bidasari Lubis; Syahril Pasaribu; Munar Lubis; Tiangsa Sembiring; Adillida Adillida
Paediatrica Indonesiana Vol 44 No 3 (2004): May 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (571.454 KB) | DOI: 10.14238/pi44.3.2004.95-100

Abstract

Objective To examine hemolysis in falciparum and vivax malarialpatients based on serum bilirubin examination.Methods A cross sectional study was conducted on childrenyounger than 15 years of age who visited public health center inthe district of Mandailing Natal with complaints of fever, shivering,pale, jaundice, diarrhea, or headache between April 9 th and April19 th 2001. Variables recorded were age, gender, body weight, bodyheight, symptoms and signs, anti malarial drugs, and laboratorytest results. Thin and thick blood smears were done as diagnostictools of malaria. Thin blood smear was also performed to deter-mine the level of malaria parasites in blood (parasitemia) and toexamine the morphology of red blood cells. Hemolysis was deter-mined by bilirubin examination.Results In P. falciparum malaria, there was a moderate correlation(r=0.68, p<0.0001) between parasitemia and indirect bilirubin con-centration. While in P. vivax malaria, there was only a weak corre-lation (r=0.46, p=0.007) between parasitemia and indirect bilirubinconcentration. It was also found that in falciparum malaria, para-sitemia, total and indirect bilirubin concentrations were significantlyhigher than that in vivax malaria, with p values of 0.009, 0.015 and0.003, respectively.Conclusion Hemolysis in falciparum malaria is more severe thanthat in P. vivax malaria, with marked elevation of indirect bilirubin.The elevation of serum bilirubin correlated with parasitemia
The effect of vitamin A supplementation on morbidity due to Plasmodium falciparum Adillida Adillida; Yoyoh Yusroh; Munar Lubis; Bidasari Lubis; Tiangsa Sembiring; Syahril Pasaribu
Paediatrica Indonesiana Vol 44 No 4 (2004): July 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (323.416 KB) | DOI: 10.14238/pi44.4.2004.133-7

Abstract

Objective To investigate the effect of vitamin A supplementationon malaria morbidity.Methods The study was a randomized double-blind placebo-con-trolled trial, conducted in Panyabungan, Mandailing Natal, NorthSumatera from April 2001 to April 2002. Children aged 6-60 monthssuffering from falciparum malaria were randomly assigned to highdose vitamin A or placebo every 4 months for a year. All childrenwere treated in accordance with health center policy. Malaria mor-bidity was assessed from health center visit due to fever, diarrhea,cough, or abdominal pain. Parents gave reports if their child re-ceived malaria treatment from other health centers.Results The number of febrile episodes (probable malaria illness)was lower in the treatment group than that of control, but not sig-nificant. The parasitemia was not different between both groups.There was a significant difference in spleen enlargement betweenthe treatment group and control (p=0.04). There was no differencein health center visit between the two groups.Conclusion The findings suggest that vitamin A supplementationhas only effect on spleen enlargement in malaria.
Scoping Review: Perbandingan antara Intermittent Fasting dengan Ketogenic Diet terhadap Penurunan Berat Badan pada Orang Dewasa dengan Obesitas Safira Pinandita Kusumah; Yoyoh Yusroh; R. Rizky Suganda Prawiradilaga
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.309

Abstract

Abstract. In the worldwide, obesity cases have increased drastically in the last 10 years, so it is a nutritional problem that needs considerable attention. In recent years there are several diet programs that are carried out by many people in the world, including the intermittent fasting (IF) and ketogenic diet (KD). The aim of this study was to compare IF with KD to weight loss in obese adults. This study adopts the method of scoping review, and the samples used are international scientific articles that have passed the screening and feasibility testing stages. The results in this study were taken from 3 different databases, Pubmed, Ovid, and Proquest according to the inclusion and exclusion criteria taken from 2011–2021. Among the 36.799 articles in the preliminary search, 4 articles were obtained for qualitative analysis. The results showed that the percentage of weight loss from the 2 IF studies had a range of 2.9-8.5%, while the 2 KD studies had a range of 3.9-10%. From this, the percentage of KD weight loss is higher than that of IF. This may be due to the lower daily calories and more time on the KD diet compared to the IF diet. Abstrak. Di seluruh dunia, obesitas mengalami peningkatan kasus secara drastis dalam 10 tahun terakhir, sehingga termasuk ke dalam masalah gizi yang perlu mendapatkan perhatian secara serius. Beberapa tahun terakhir terdapat beberapa program diet yang banyak dilakukan oleh masyarakat, diantaranya intermittent fasting (IF) dan ketogenic diet (KD). Tujuan penelitian ini untuk membandingkan IF dengan KD terhadap penurunan berat badan pada orang dewasa dengan obesitas. Penelitian ini menggunakan metode scoping review dan sampel yang digunakan merupakan artikel ilmiah internasional yang sudah melewati fase skrining dan uji kelayakan. Hasil dari penelitian ini diambil dari 3 database yang berbeda, yaitu Pubmed, Ovid, dan Proquest sesuai kriteria inklusi dan eksklusi yang diambil dari tahun 2011–2021. Dari 36.799 artikel yang diperoleh pada pencarian awal, didapatkan 4 artikel yang dianalisis secara kualitatif. Hasil penelitian memperlihatkan bahwa persentase penurunan berat badan dari 2 penelitian IF yaitu 2,9-8,5%, sedangkan 2 penelitian KD 3,9-10%. Berdasarkan data tersebut terlihat bahwa persentase penurunan berat badan KD lebih tinggi dibandingkan dengan IF. Hal tersebut mungkin disebabkan karena rendahnya asupan kalori harian pada diet KD dan waktu yang dibutuhkan pada diet KD lebih lama dibandingkan diet IF.