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All Journal Hemera Zoa JURNAL ILMU KEFARMASIAN INDONESIA
Bambang Ponco Priosoeryanto
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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Microscopical and immunohistochemical studies on intestinal signet-ring cell and pulmonary bronchiolar-alveolar carcinoma in cat Bambang Ponco Priosoeryanto; Ryoji Yamaguchi; Susumu Tateyama; Koudai Matsuyama
Hemera Zoa Vol. 75 No. 2 (1992): Jurnal Hemera Zoa
Publisher : Hemera Zoa

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Abstract

A rare case of signet-ring cell (SRC) carcinoma of the intestines occurring in a cat, 9,5 years old, female was described.
Perbandingan Profil Lipid pada Tikus Putih yang diberi Crude Fucoidan dari Rumput Laut Coklat (Sargassum polycystum) yang Diinduksi Diet Tinggi Lemak Juliana Irem Adriana Purukan; Kusmardi Kusmardi; Dian Ratih Laksmitawati; Syamsudin Abdillah; Bambang Ponco Priosoeryanto
JURNAL ILMU KEFARMASIAN INDONESIA Vol 17 No 1 (2019): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (923.043 KB) | DOI: 10.35814/jifi.v17i1.648

Abstract

: Brown seaweed (Sargassum polycystum) is one of the plants that produces pharmacological activity which is as anti-atherosclerotic with the potential chemical content is fucoidan. The aim of this research is to know the effectiveness of crude fucoidan in decreasing total cholesterol, LDL, TG, increasing HDL levels and atherogenic index. In the optimization phase, 5 rat test animals were used to see the effect of the composition of a high-fat diet given on lipid profiles. While in the testing phase 30 test animals were divided into 6 groups to see the effect of a high-fat and crude fucoidan diet given to lipid profiles. Examination of lipid profiles was carried out three times, namely on the 0th, 14th and 36th days, after that the atherogenic index is calculated. On the 36th day the test, rats were anesthetized and necropsy for subsequent blood collection through the heart organ.The results showed that 200 mg crude fucoidan dose could significantly decreasing total cholesterol, LDL, TG, increased HDL levels and significantly decreased the atherogenic index of rat serum compared to the dosages of 100 mg and 50 mg, but did not differ significantly from the positive control at 10 mg atorvastatin.
Co-Authors Dian Ratih Laksmitawati Juliana Irem Adriana Purukan Koudai Matsuyama Kusmardi Kusmardi Ryoji Yamaguchi Susumu Tateyama Syamsudin Abdillah