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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) As-syifaa Jurnal Farmasi Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal farmasi UIN Alauddin Makassar
Syamsu Nur
Akademi Farmasi Kebangsaan Makassar
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Green Synthesis Nanopartikel Perak (Agnps) Terkonjugasi Etil Parametoksi Sinamat (Epms) sebagai Bahan Tabir Surya: Green Synthesis of Nanopartikel Perak (Agnps) Terkonjugasi Etil Parametoksi Sinamat (Epms) Sebagai Bahan Tabir Surya Agustina Agustina; Munawarah Munawarah; Stefanus Agustinus Lumi; Syamsu Nur
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 4 No. 2 (2018): (October 2018)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (333.247 KB) | DOI: 10.22487/j24428744.2018.v4.i2.10440

Abstract

Green Synthesis is a method to make silver nanoparticles (AgNPs) by utilizing natural materials as bioreductors. One of the natural materials that can reduce metal ions is Kaempferia galanga rhizome because it has a chemical component that can penetrate the metal. The compounds are ethyl paramethoxycinnamate (EPMC) which is used as sunscreen. This study aims to produce AgNPs conjugated with EPMC that can be used as raw material sunscreen. This study was conducted by extracting EPMS from the Kaempferia galanga rhizome and synthesizing the AgNPs conjugated with EPMC. The synthesis results were characterized by UV-Vis Spectrophotometry, FTIR, SEM, PSA and sunscreen activity. Extracted result was obtained crystalline is ethyl paramethoxycinnamate compound with yield 2,3%. The characterization of EPMC with UV-Vis spectrophotometer was obtained maximum wavelength of 308 nm and FTIR analysis result at wave number 1701,27 cm-1 indicated the presence of carbonyl group (C = O) and 1165,97 cm-1 presence of C-O and showed specific characteristic from EPMS. Characterization of AgNPs using Uv-Vis spectrophotometer was obtained maximum wavelength of 469 nm. Characterization of AgNPs using SEM are spherical and monodispers forms. Then, particle size using PSA obtained an average diameter of 182 nm. AgNPs conjugated with EPMS has a sunscreen activity with sunblock category and successfully provide protection against UV exposure at low concentration (200 ppm) categorized as ultra protection with SPF value 36,4.
UJI AKTIVITAS ANTIOKSIDAN DARI BEBERAPA EKSTRAK KULIT BATANG JAMBLANG (Syzygium cumini) MENGGUNAKAN METODE PEREDAMAN RADIKAL 2,2-DIPHENYL-1-PICRYLHYDRAZYL (DPPH) Fitriyanti Jumaetri Sami; Syamsu Nur; Sukriani Kursia; Sahibuddin A Gani; Trito Reski Sidupa
Jurnal Farmasi UIN Alauddin Makassar Vol 4 No 4 (2016): Jurnal Farmasi
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v4i4.2249

Abstract

Jamblang (Syzygium cumini) merupakan salah satu buah lokal Indonesia. Semua bagian tanaman ini dapat digunakan untuk pengobatan salah satunya sebagai antioksidan. Tujuan dari penelitian ini adalah untuk menentukan potensi antioksidan dari beberapa ekstrak kulit batang jamblang dengan menggunakan kuarcetin sebagai pembanding. Kulit batang jamblang diekstraksi secara refluks dengan menggunakan pelarut etanol, etil asetat, dan n-heksan kemudian di uji potensi antioksidannya. Hasil penelitian diperoleh nilai IC50 ekstrak etanol kulit batang jamblang sebesar 164,3 ppm, ekstrak etil asetat kulit batang jamblang sebesar 237,7 ppm, ekstrak n-heksan kulit batang jamblang sebesar 5235,6 ppm. Berdasarkan hasil tersebut dapat disimpulkan bahwa ekstrak etanol kulit batang jamblang memberikan aktivitas antioksidan yang lebih kuat jika dibandingkan dengan ekstrak lainnya. Namun hasil tersebut masih lebih kecil jika dibandingkan dengan kuarcetin dengan nilai IC50 4,57 ppm.
UJI AKTIVITAS TABIR SURYA PADA BEBERAPA SPESIES DARI FAMILY ZINGIBERACEAE DENGAN METODE SPEKTROFOTOMETRI Fitriyanti Jumaetri Sami; Syamsu Nur; Megawati M. Martani
As-Syifaa Jurnal Farmasi Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.875 KB) | DOI: 10.33096/jifa.v7i2.8

Abstract

Testing activity sun screen of several species from family Zingiberaceae with a spectrophotometric method have been. Study purpose is to obtain data on the sunscreen activity of ginger extract Z. officinale var. Officinale, Z. officinale var. Rubrum and Zingiber zerumbet SM and their combination with the parameters of % transmission of erythema, % transmission of pigmentation and SPF. The method used an experimental laboratory. Evaluation of the activity of ethanol extract of Z. officinale var. Officinale, Z. officinale var. Rubrum and Zingiber zerumbet SM made by maceration method using 70% ethanol. The test is based on the ability of the absorb the rays ultraviolet. Research carried out by the respective concentrations of ethanol extract of Z. officinale var. Officinale, Z. officinale var. Rubrum and Zingiber zerumbet SM of 200 ppm , 400 ppm , 600 ppm, 800 ppm and 1000 ppm. Based on percent transmission of erythema and percent transmission of pigmentation at a concentration of 1000 ppm, respectively ethanol extract Z. officinale var. Officinale, Z. officinale var . Rubrum and Zingiber zerumbet SM could be used as a sunscreen but still weak to be used as sunscreen ingredients. The result showed that combined Z. officinale var. Officinale, Z. officinale var. Rubrum and Zingiber zerumbet SM at a concentration of 500 ppm obtained percentage value of 1% transmission of erythema and 3,9% of pigmentatied transmission and categories as sunblock with SPF value is 50 protection.
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN BEROMA (Cajanus cajan (L.) Milps) Mirnawati Salampe; Zulfaidah Rahma; Syamsu Nur; Sukamto S Mamada
Majalah Farmasi dan Farmakologi Vol. 23 No. 1 (2019): MFF
Publisher : Faculty of Pharmacy, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1223.467 KB) | DOI: 10.20956/mff.v23i1.6464

Abstract

Daun beroma (Cajanus cajan (L.) Milps) berpotensi sebagai antioksidan dikaitkan dengan kandungan senyawa kimia yaitu flavanoid dan fenolik. Aktivitas antioksidan dari ekstrak etanol 70% daun Cajanus cajan (L.) Milps dilakukan menggunakan metode 1,1- diphenyl-2-picrylhydrazyl (DPPH) dan 2,2’-azino-bis- [3- ethylbenzothiazoline sulphonate] (ABTS). Nilai IC50 pada pengujian metode DPPH yaitu 86,34 mg/ml dan IC50 pada metode ABTS yaitu 20,53 mg/ml. Berdasarkan nilai IC50 tersebut, dapat disimpulkan bahwa ekstrak etanol daun Cajanus cajan (L.) Milps mempunyai aktivitas antioksidan yang sangat kuat.
Co-Authors Agustina Agustina Fitriyanti Jumaetri Sami Megawati M. Martani Mirnawati Salampe Munawarah Munawarah Sahibuddin A Gani Stefanus Agustinus Lumi Sukamto Salang Mamada Sukriani Kursia Trito Reski Sidupa Zulfaidah Rahma