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All Journal ADITYA - Pendidikan Bahasa dan Sastra Jawa International Journal Pedagogy of Social Studies Jurnal Review Pendidikan dan Pengajaran (JRPP) Health Information : Jurnal Penelitian Nautical: Jurnal Ilmiah Multidisiplin Indonesia Jurnal Ilmiah Research and Development Student Jurnal Multidisipliner Kapalamada
Ani Rahayu
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Religion Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Health Information : Jurnal Penelitian

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Anticancer Activity of Turmeric Rhizome Extract (Curcuma longa Linn) In-vitro Against MCF7 Breast Cancer Line Cells Halimatushadyah, Ernie; Rahayu, Ani
Health Information : Jurnal Penelitian Vol 15 No 2 (2023): Mei-Agustus
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v15i2.914

Abstract

Turmeric or Curcuma longa Linn is one of the native spices and medicinal plants from Southeast Asia. Turmeric contains a compound named curcumin. Curcumin (diferuloylmethane) is a yellow pigment in turmeric that is widely used as a spice, food coloring (curry) and preservative. Curcumin shows various pharmacological effects that have been reported scientifically in research, one of which is as an anticancer. This study aims to perform a cytotoxic test of turmeric rhizome extract (Curcuma longa Linn) in-vitro with the Microtetrazolim (MTT) assay method to grasp and determine the effect of preventing the growth of MCF7 breast cancer cells, so that the IC50 value can be known. In this study, it was found that turmeric rhizome extract can be used as a natural ingredient that has the potential to inhibit the growth of MCF7 breast cancer cells. Turmeric rhizome extract has the effectiveness to inhibit the growth of MCF7 breast cancer cells with an IC50 value of 26.30 ppm. This value is categorized as moderate or moderately active cytotoxic.
Co-Authors Ahmad Fuad Afdhal Anggraini, Tiara Widya Bella, Hanum Salsa Erin Pebriani Feriadi Suwarna Halimatushadyah, Ernie Hasan, Delina Jadidah, Ines Tasya Julinda Julinda Julinda, Julinda Nopriani, Hilda Okpri Meila, Okpri Pebriani, Erin Primadona, Desti Saipul Annur Talia, Jeny Vannisa, Saprina Putri Wulandari, Anisa