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Antioxidant Activities of Soursop Leaves and Meniran Plant Extracts Combination Wimpy Wimpy; Livana PH; Putrie Prameswari
Indonesian Journal of Global Health Research Vol 4 No 1 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.859 KB) | DOI: 10.37287/ijghr.v4i1.803

Abstract

Antioxidants can prevent free radicals which from the metabolism of the body, air pollution and contamination of food. Soursop leaves has a good potential as an antioxidant because it contains alkaloids, tannins, flavonoids and saponins. Meniran has a good potential as an antioxidant because it contains alkaloids, tannins, flavonoids and steroids. The combination of soursop leaves extract and meniran extract can provide very strong antioxidant activity than its singular forms. The aim of this study is to determine the antioxidant activity of the combination of soursop leaves extract and meniran extract compared to the singular forms. This research was done at the BPTO Tawangmangu Central Java, Indonesian and Chemical Laboratory, STIKES Nasional from October to December 2016. This type of research was experimental with quota sampling technique. The results showed that IC50 value of singular forms of soursop leaves extract was 116,5376 ppm. IC50 value of singular forms of meniran extract was 30,6893 ppm. IC50 value of combination forms of soursop leaves extract and meniran extract with ratio of 1:1 was 41,4710 ppm. IC50 value of combination forms of soursop leaves extract and meniran extract with ratio of 1:2 was 23,8590 ppm. IC50 value of combination forms of soursop leaves extract and meniran extract with ratio of 2:1 was 56,5174 ppm. The combination of soursop leaves extract and meniran extract had very strong antioxidant activity compared to its singular forms. The combination soursop leaves extract and meniran with ratio of 1:2 had the strongest antioxidant activity.
Antioxidant Activities of Soursop Leaves and Meniran Plant Extracts Combination Wimpy Wimpy; Livana PH; Putrie Prameswari
Indonesian Journal of Global Health Research Vol 4 No 1 (2022): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.859 KB) | DOI: 10.37287/ijghr.v4i1.803

Abstract

Antioxidants can prevent free radicals which from the metabolism of the body, air pollution and contamination of food. Soursop leaves has a good potential as an antioxidant because it contains alkaloids, tannins, flavonoids and saponins. Meniran has a good potential as an antioxidant because it contains alkaloids, tannins, flavonoids and steroids. The combination of soursop leaves extract and meniran extract can provide very strong antioxidant activity than its singular forms. The aim of this study is to determine the antioxidant activity of the combination of soursop leaves extract and meniran extract compared to the singular forms. This research was done at the BPTO Tawangmangu Central Java, Indonesian and Chemical Laboratory, STIKES Nasional from October to December 2016. This type of research was experimental with quota sampling technique. The results showed that IC50 value of singular forms of soursop leaves extract was 116,5376 ppm. IC50 value of singular forms of meniran extract was 30,6893 ppm. IC50 value of combination forms of soursop leaves extract and meniran extract with ratio of 1:1 was 41,4710 ppm. IC50 value of combination forms of soursop leaves extract and meniran extract with ratio of 1:2 was 23,8590 ppm. IC50 value of combination forms of soursop leaves extract and meniran extract with ratio of 2:1 was 56,5174 ppm. The combination of soursop leaves extract and meniran extract had very strong antioxidant activity compared to its singular forms. The combination soursop leaves extract and meniran with ratio of 1:2 had the strongest antioxidant activity.
Hubungan Kadar Merkuri dalam Darah terhadap Jumlah Limfosit Absolut pada Komunitas Ibu-Ibu di Muara Angke Putrie Prameswari; Tri Harningsih
Jurnal Farmasetis Vol 12 No 4 (2023): Jurnal Farmasetis: November 2023
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/far.v12i4.1216

Abstract

Merkuri dapat membahayakan kehidupan hewan air dan kesehatan manusia. Merkuri dapat terlepas ke lingkungan melalui aktivitas manusia seperti pada kebakaran hutan, pengolahan dan pembakaran batu bara, pembakaran sampah, pengolahan logam besi, perak emas dan lain-lain. Muara Angke merupakan suatu sungai yang bermuara ke Teluk Jakarta. Pembuangan limbah domestik dan industri tanpa mengalami pengolahan terlebih dahulu dapat mengakibatkan pencemaran lingkungan. Merkuri ditemukan ditemukan di perairan kawasan Muara Angke. Limfosit merupakan salah satu dari jenis sel leukosit yang berpengaruh apabila terpapar akibat merkuri. Penelitian ini untuk mengetahui korelasi kadar merkuri dalam darah terhadap jumlah limfosit absolut pada komunitas ibu – ibu di Muara Angke, dengan jumlah responden sebanyak 15 orang.  Teknik sampling mengunakan quota sampling. Jenis penelitian adalah observasional deskriptif analitik  desain Cross Sectional. Responden merupakan ibu – ibu di Muara Angke. Kadar merkuri dalam darah merupakan variabel independen. Jumlah limfosit absolut merupakan variabel dependen. Kadar merkuri diukur dengan metode ICP-MS menggunakan alat Agilent 7700 X. Jumlah limfosit absolut diukur dengan metode Fluorescence Flow Cytometry menggunakan alat Sysmex XN 550. Hasil pemeriksaan merkuri pada darah 15 responden didapatkan kadar merkuri tinggi yaitu 2 responden, dan kadar merkuri normal sebanyak 13 responden. Limfosit absolut setelah diperiksa menunjukkan jumlah limfosit lebih dari normal sebanyak 3 responden dan jumlah limfosit normal sejumlah 12 responden. Hasil uji korelasi Spearman diperoleh p = 0,018, r = 0,471. Ada korelasi kadar merkuri dalam darah terhadap jumlah limfosit pada penduduk di Muara Angke.