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Evaluasi Penggunaan Obat Pada Pasien Gastritis di Puskesmas Kaladawa Periode Oktober-Desember 2018 Osie Listina; Yanuar Prasetyo; Devi Ika Kurnianingtyas Solikhati; Fitria Megawati
Jurnal Ilmiah Medicamento Vol 7 No 2 (2021): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v7i2.1911

Abstract

Abstrak Gastritis merupakan peradangan yang mengenai dinding lambung. Berdasarkan penelitian yang dilakukan oleh Depertemen Kesehatan RI angka kejadian gastritis di Indonesia yang tertinggi mencapai 91,6% yaitu di kota Medan. Penyebab gastritis paling sering yaitu infeksi oleh bakteri H. pylori,namun dapat pula diakibatkan oleh bakteri lain seperti H. heilmanii, Streptococci, Staphylococci, Protecus species, Clostridium species, E.coli, Tuberculosis dan Secondary syphilis. Tujuan dilakukannya penelitan ini untuk mengetahui gambaran penggunaan obat pada pasien gastritis di Puskesmas Kaladawa periode Oktober-Desember 2018 serta untuk mengkaji rasionalitas penggunaan obat pada pasien gastritis berdasarkan tepat cara pemberian, tepat indikasi, tepat pemilihan obat dan tepat dosis. Penelitian ini merupakan penelitian non eksperimental dengan metode deskriptif. Data yang digunakan dalam penelitian ini adalah data sekunder berupa resep dan rekam medik pasien yang menderita penyakit gastritis. Berdasarkan hasil penelitian dapat disimpulkan bahwa penggunaan obat gastritis di Puskesmas Kaladawa Periode Oktober-Desember 2018 dari 95 kasus, setelah dikaji kerasionalannya berdasarkan kriteria 4T diperoleh hasil ketepatan indikasi sebesar 100%, ketepatan obat sebesar 90%, ketepatan dosis sebesar 100%, dan tepat cara pemberian sebesar 100%. Kata Kunci: kerasionalan penggunaan obat, evaluasi penggunaan obat, gastritis Abstract Gastritis is an inflammation that concerning with gastric wall. Based on research conducted by departemen kesehatan RI Medan is a city that has the highest gastritis incidence numbered 91,6%. Gastritis can be caused by several factors like H. pylori,H. heilmanii, Streptococci, Staphylococci, Protecus species, Clostridium species, E.coli, Tuberculosis and Secondary syphilis. The purposes of this reseach was to find out description drug use in gastritis patients at Puskesmas Kaladawa in the period of October-December 2018 and to assess the rationality of drug use in gastritis patients based on right medication, right of drugs and right dose. This research was a non-experimental research with descriptive method. The data used in this study was secondary data in the form of prescriptions and medical records of patients suffering from gastritis. Based on the result of the study it can be concluded that the use of gastritis drugs at Puskesmas Kaladawa in the period October-December 2018 from 95 cases, after studied its reliability based on 4T criteria the results were the accuracy of the indication was 100%, the accuracy of the drug was 90%, the accuracy of the dose was 100%, and the exact method of administration was 100%. Keywords: rationality of drug use, evaluation of drug use, gastritis.
Uji Aktivitas Afrodisiaka Sediaan Tablet Effervescent Ekstrak Kombinasi Buah Pare (Momordica charantia L.) dan Bawang Putih (Allium sativum L.) pada Mencit Putih Jantan (Mus musculus L.) Osie Listina
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7467

Abstract

Aphrodisiac is a medicinal and food ingredient that can arouse sexual desire. The purpose of this study was to determine the effect of aphrodisiac effectiveness and the effect of aphrodisiac activity on effervescent tablets of bitter melon extract (Momordica charantia L) and garlic (Allium sativum L) single and combination on male white mice (Mus musculus). In this study using the ICC method (introduction, claimbing, coitus) on 25 male mice wistar strain which were divided into 5 groups. Treatment group I as a negative control, which was administered aquadest orally. Then group II was given a solution of effervescent tablets single dose of bitter melon fruit 980mg / KgBB. Furthermore, group III was given a solution of effervescent tablets of a single dose of garlic 150mg / KgBB. treatment group IV was given a solution of effervescent tablets combination 1/2 : 1/2 bitter melon fruit extract 490mg / KgBB and garlic 75mg / kgBB. Treatment group V was given a combination effervescent tablet solution of 1: 1 extract of bitter melon fruit 980mg / KgBB and garlic 150mg / KgBB. Then observed and calculated the number of ICCs for 2 hours. The results obtained were then processed using SPSS ANOVA and Post Hoc follow-up tests. The results showed that all treatment groups had significantly different aphrodisiac effects, but the best frequency of aphrodisiac activity showed that the combination of 1: 1 extract of bitter melon 980mg / KgBB and garlic 150mg / KgBB had the most frequency value using the ICC method when compared to other effervescent tablet formulations.