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UJI EFEK ANTIDIARE EKSTRAK RIMPANG KUNYIT (Curcuma domestica val.) PADA MENCIT JANTAN Linta Meliala; Winda Sari; Palas Tarigan
Jurnal Penelitian Farmasi & Herbal Vol 2 No 2 (2020): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v2i2.208

Objectives : The purpose of this study to determine the effect and dose of effective use of rhizome extract of turmeric as antidiarrhea in male mice induced castor oil and the use of rhizome extract of turmeric equivalent to Loperamid HCl. Method : This research method is carried out experimentally with the research stages of sample preparation, sample characterization, simplicia screening, preparation of extracts, preparation of animal experiments and testing of antidiarrheal effects in experimental animals. Results : The results showed that the results of phytochemical screening of simplicia powder and turmeric rhizome extract contained flavonoids and tannins. SPSS statistical test results (statistical package for the social science) continued with defference test of Duncan average, the duration of the occurrence of diarrhea showed that the control group of Loperamid HCl dose 1 mg/kg bw gave significant effect on turmeric rhizome extract at doses of 40 mg/ kg bw and doses 80 mg/kg bw. The shorter the time of diarrhea, the stronger the antidiarrheal effect. Conclusion : Turmeric rhizome extract dose 20 mg/kgbw showed that dose 20 mg/kgbw has antidiarrhea effect more than lower than Loperamid HCl dose 1 mg/kg bw. Turmeric rhizome extract dose 40 mg/kg bb has same effect with Loperamid HCl dose 1 mg/kgbb. And turmeric rhizome extract dose 80 mg/kgbb has effect more potencial that Loperamid HCl dose 1mg/kg bw. There is a relationship between the size of the dose with the antidiarrheal effect that occurs.

UJI AKTIVITAS INFLAMASI EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) TERHADAP TIKUS PUTIH JANTAN (Galur wistar) Delisma Simorangkir; Jenti Hutagalung; Palas Tarigan
Jurnal Penelitian Farmasi & Herbal Vol 2 No 2 (2020): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v2i2.236

Background: Inflammation is a protective response of the body from the injury of the cell. Edema is one of the inflammation symptoms. Drumstick (Moringa oleifera L.) contains flavonoid a major of a bioactive constituent. Flavonoids inhibit COX-2 in inflammatory in mice. Objective: This study aims to investigate and to determine the anti-inflammatory activity and its effective dose extract. Method: Experimental. The extract was prepared by maceration method using ethanol 80%. An anti-inflammatory activity test was performed in five different groups. Each group consisted of 5 rats. The 1st group (negative control) was given 0,5% CMC-Na suspension, the 2nd group (positive control) was given diclofenac sodium 2,25 mg/kg BW, the 3rd, 4th, and 5th groups were successively given the drumstick leaf extract as much as 100, 150, and 200 mg/kg BW. Each rat was then induced by 1% carrageenan and tested using the subplantar method. The inflamed paw volume was measured using plestymometer. The measurements were done for 3 hours long with intervals of 30 minutes. The data were statistically analyzed using ANOVA (Analysis of Variance). Results: The results showed that the negative control had a significant difference with the other treatment groups which did not show any anti-inflammatory effect. Conclusion: Extract of a drumstick at a dose of 200 mg/kg BW has a better anti-inflammatory effect than ethanolic of a drumstick at dose of 100, 150 mg/kg BW, but still under sodium diclofenac.

PENYULUHAN TENTANG MANFAAT RUMPUT MUTIARA TERHADAP PENYEMBUHAN PENYAKIT REMATIK PADA USIA 40 TAHUN KE ATAS DI PUSKESMAS DELI TUA Linta Meliala; Palas Tarigan
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Rheumatism. are sicknesses that assault joints and designs issues in around joints.Rheumatic illnesses that are frequently found are osteoarthritis because of degeneration or maturing processes, rheumatoid joint inflammation, immune system infections and gout because of high uric corrosive. In the older, this illness regularly happens with the goal that it now and then causes aggravations in the personal satisfaction in the old. As a general rule, the indications of stiffness in every quiet are diverse because of contrasts in the resistant reaction of every individual. Coming up next are the most well-known side effects found in rheumatic sicknesses, in particular: joint agony, expanding in the joints, firmness in the joints, warmth and redness in the joint region, weakness, fever, weight reduction. Illnesses ailment can be forestalled and furthermore gave treatment health,with counseling.this is normal knowledge.elderly and their famil can work on with regards to ailment this strategy utilized in. advising iniiskaji.tindak(action research).The result from augmentation ini is there is an increment in the information on the old with regards to ailment, anticipation and treatment.

PENYULUHAN TENTANG MANFAAT DAUN GAMBIR (Uncaria gambir (Hunter) Roxb.) SEBAGAI OBAT KUMUR DI DESA PATUMBAK Zola Efa Harnis; Bunga Rimta Barus; Palas Tarigan
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Gambir is a latex juice extracted from the leaves of the gambier plant (UncariagambirRoxb) by pressing. Gambir contains two main components, namely catechins and catechutannic acid, which has many benefits. Gambir has astringent, antibacterial, and other pharmacological and toxic properties. Gambir in Indonesia is generally used for betel nut, besides that it is also used to treat canker sores and mouthwash for sore throats. This counseling aims to obtain data on counseling about the benefits of gambir leaves as mouthwash in Patumbak Village. Counseling was carried out using an interactive method between the presenters and participants so that the event took place in an interesting manner and provided education to the community about the benefits of gambir leaves as mouthwash in Patumbak Village. The results obtained from this counseling are lack of understanding or lack of knowledge of the community following counseling in Patumbak Village about the benefits of gambir leaves as mouthwash, by providing guidance and assistance with counseling methods, the results obtained where the community, especially those who participated in the counseling, showed enthusiasm in their curiosity about the benefits of the leaves. gambier as a mouthwash as well as increasing experience and knowledge of the people of Patumbak Village who participated together in counseling the benefits of gambir leaves as mouthwash through materials and simulations obtained during socialization. The conclusion of this counseling is that the community has been able to find out the benefits of gambier leaves that can be used as mouthwash.

PENYULUHAN TENTANG PEMBERIAN OBAT RANITIDIN TERHADAP PASIEN GASTRITIS DI PUSKESMAS DELI TUA Linda Margata; Palas Tarigan
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Gastritis is the most widely recognized wellbeing problem in the wellbeing place. Gastritis is a condition of aggravation or draining in the gastric mucosa that can be intense, persistent, diffuse or nearby. The two most normal kinds of gastritis are intense shallow gastritis and atrophic gastritis. In daily existence, gastritis is whined of like awful desire for the upper midsection, for instance the stomach is in every case full, queasiness, feeling hot in the stomach, torment previously or subsequent to eating, etc (Oka, 2018). Pharmacological treatment to treat gastritis sickness can be indicative treatment used to hinder corrosive emission and increment mucosal protection from corrosive. Medications utilized, for example, different stomach settling agents that for the most part contain aluminum hydroxide, magnesium hydroxide or calcium carbonate and histamine receptor inhibitor drugs H stomach, for example, simetidin, ranitidine, nizatidin, and famotidin that adequately lessen the corrosive reaction (Oka, 2018). Ranitidine is a class of acid neutralizer drugs utilized for the treatment of stomach and duodenal ulcers, esophagitis reflux, neurotic hypersecrescence states (which are broadly utilized by the public Side effects of gastritis torment notwithstanding indigestion likewise cause manifestations like sickness, retching, shortcoming, bulging, feeling claustrophobic, craving diminished, pale face, internal heat level up, cool sweats, wooziness, continually burping and in more serious conditions, can upchuck blood (Shamsu, 2017). The Middle for General Wellbeing (Puskesmas) is a medical services office that coordinates general wellbeing endeavors and top notch individual wellbeing endeavors, focusing on promotive and preventive endeavors, to accomplish the most elevated level of general wellbeing in their workspace. Puskesmas has the assignment of executing wellbeing strategy to accomplish wellbeing improvement objectives in its workspace to help the acknowledgment of sound subdistricts (Permenkes, 2014).

PENYULUHAN TENTANG MANFAAT DAUN KELOR TERHADAP LUKA BAKAR DI PUSKESMAS TANJUNG MORAWA Wahyudi Wahyudi; Palas Tarigan
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Direction on the benefits of kelor leaf for the burn treatment at the cape morawa center was shown to apply the information and development students acquired in broader local conversations. To the burns at cape morawa center. The kelor leaf (moringa oleifera lam) has many health benefits, one of which is the burning skin. Burns are tissue damage caused by contact with hot sources, such as fire, hot water, chemicals, electricity, and radiation. Burns are found in skin, mucus membranes, respiratory tract, and digestive tract. Symptoms of pain, swelling, red, abrasions. The most improved thing to do with burns is to provide local therapy with the intention of recovering as quickly as possible. The reason for this PKM is to get data on the kelor leaf application (moringa oleifera lam). Flavonoid and leaf leaf tannin play a role in treating burns.

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