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The Significance of Troponin and Ck-Mb in Association with Q-Wave Myocardial Infarction Harahap, Urip; Margata, Linda
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 1 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (746.21 KB) | DOI: 10.32734/idjpcr.v1i1.199

Abstract

Abstract. Acute myocardial infarction (AMI) is the global main cause of morbidity and mortality. AMI describes the process of cell death due to prolonged ischemia identified by the appearance of pathological Q-wave in electrocardiogram (ECG). Myocardial cell death does not occur directly after the onset of myocardial ischemia, however, it occurs more than 6 hours after the onset. Thus, certain cardiac markers, such as cardiac troponin and creatinine kinase-MB (CK-MB) which formed in myocardial cell damage, play a vital role in diagnosing AMI. Keywords: Cardiac Biomarker, CK-MB, Diagnosis, Q-wave Myocardial Infarction, Troponin
ANALISIS FAKTOR YANG BERHUBUNGAN DENGAN KUNJUNGAN PASIEN DALAM PEMANFAATAN PELAYANAN KESEHATANA DI POLI UMUM PUSKESMAS BAH BOLON KABUPATEN SIMALUNGUN TAHUN 2019 Margata, Linda; Girsang, Rostiodertina
Jurnal Kajian Kesehatan Masyarakat Vol 1 No 1 (2019): Jurnal Kajian Kesehatan Masyarakat
Publisher : Fakultas Kesehatan Masyarakat, Institut Kesehatan Deli Husada Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jk2m.v1i1.863

Abstract

Puskesmas is a community first aid center. Therefore the Puskesmas was established in the community. Utilization of health services is the process of interaction or relationship between consumers who use services and health service providers. The service process provided starts from the registration stage until the patient gets treatment and healing. This study aims to determine the relationship of facilities and infrastructure, human resources, and distance with the utilization of health services at Bah Bolon Health Center, Simalungun Regency in 2019. This type of research uses analytic descriptive with cross sectional approach with sampling technique using Non Probability Sampling with Accidental Sampling technique. The number of samples in this study were 77 respondents namely Patients who used the Bah Bolon Puskesmas Service. Data were obtained using a questionnaire then in the data analysis using logistic regression test. Based on the analysis of the logistic regression test the most dominant variable associated with the low utilization of health services at the Bah Bolon Health Center is Facilities and Infrastructure the value of p = 0.037 and OR = 3.205. It can be concluded that incomplete Facilities and Infrastructure is a factor in the low utilization of services at the Bah Bolon Health Center in Simalungun District, which is 3,205 times more influential than the Puskesmas with complete facilities and infrastructure.
PENGARUH PELATIHAN SUMBER DAYA MANUSIA (SDM) DAN MOTIVASI KERJA TERHADAP PRODUKTIVITAS KERJA PEGAWAI DI UPT PELATIHAN KESEHATAN PROVINSI SUMATERA UTARA TAHUN 2019 Margata, Linda; Hariati, Hariati; barus, dewi
Jurnal Inovasi Kesehatan Masyarakat Vol 1 No 2 (2020): Jurnal Inovasi Kesehatan Masyarakat
Publisher : Fakultas Kesehatan Masyarakat, Institut Kesehatan Deli Husada Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jikm.v1i2.873

Abstract

In improving the skills and skills of employees through their participation in training and education programs, it is hoped that improving the performance of employees will thus have a positive impact on employee work productivity because it will increase and automatically increase the productivity of the company. The study aims to determine the effect of training in Human Resources (HR) and work motivation on work productivity of employees in the UPT Health Training Province of North Sumatra in 2019. The study used an analytical survey with a cross sectional design. The population of this study all employees of the North Sumatra Province Health Training UPT who were active in January 2019 as many as 60 people. The sampling technique used the total sampling method. Data analysis was performed by univariate, bivariate analysis with chi square and multivariate with logistic regression test at α = 0.05. The results of the study that the training of Human Resources (HR) had an effect on employee work productivity (0,002) and work motivation had an effect on employee work productivity (0,000). From the training variables of Human Resources (HR) and work motivation that influence employee work productivity, namely work motivation. The conclusion of this study was the influence of training in Human Resources (HR) and work motivation on work productivity of employees at the UPT Health Training Province of North Sumatra in 2019. It is recommended that employees can motivate themselves to take part in training with work motivation to learn things that support performance they increase employee productivity
Application of Fourier Transform Infrared Spectrophotometry Method for Analysis of Metformin Hydrochloride in Marketed Tablet Dosage Form Nerdy Nerdy; Linda Margata; Dian Ika Perbina Meliala; Bunga Mari Sembiring; Selamat Ginting; Effendy De Lux Putra; Atika Mulyati; Tedy Kurniawan Bakri
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 7, No. 2, November 2021
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v7i2.22158

Abstract

The first line drug given for monotherapy for diabetes mellitus type 2 is metformin hydrochloride, which is a biguanide antihyperglycemic drug. The aim of this research was to develop, validate, and apply the Fourier Transform Infrared spectrophotometry method to identify and determine metformin hydrochloride in marketed tablet dosage form. This research included preparation of standard, analysis of samples, and validation of method. The specific wavenumber obtained for qualitative analysis was 1645.68 cm–1 and 1574.8 cm–1. The specific area obtained for quantitative analysis with a single baseline ranged from 1701.53 cm–1 to 1535.66 cm–1. All metformin hydrochloride marketed tablet dosage forms were analyzed and met all of the qualitative and quantitative requirements. The methods met the requirements of method validation for accuracy with a percentage of recovery of 100.22 %, precision with relative standard deviation of 0.48 %, linearity with a correlation coefficient of 0.9992, limit of detection of 11.17 mg per mL, limit of quantitation of 33.84 mg per mL, and good specificity results. In this study, the Fourier Transform Infrared spectrophotometry method was successfully developed and validated for application in identification and determination of metformin hydrochloride in marketed tablet dosage form.
PERBANDINGAN EFEKTIVITAS EKSTRAK DAN JUS BUAH BIT (Beta vulgaris L.) TERHADAP PENURUNAN KOLESTEROL TIKUS PUTIH Linda Margata; Dewi Sartika Br Haloho; Parhan Parhan
Jurnal Penelitian Farmasi & Herbal Vol 3 No 1 (2020): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i1.330

Abstract

Kandungan pada buah bit diketahui mampu menurunkan kolesterol dengan cara menghambat pembentukan asam glutarat. Penelitian ini bertujuan untuk membandingkan efek penurunan kolesterol ekstrak dan jus buah bit pada tikus putih. Penelitian ini menggunakan 24 ekor tikus yang dibagi menjadi empat kelompok. Pada penelitian ini tikus diinduksi dengan propiltiourasil (PTU) selama 10 hari lalu masing-masing kelompok diberikan: CMC Na, simvastatin, ekstrak buah bit, dan jus buah bit selama 15 hari. Data penelitian diolah dengan program SPSS menggunakan ANAVA satu-jalur dengan signifikansi 0,05. Kolesterol total sebelum perlakuan pada jus buah bit yaitu 306 mg/dl dan pada ekstrak 311 mg/dl. Kadar kolesterol total setelah perlakuan yaitu 103 mg/dl pada jus dan 148 mg/dl pada ekstrak. Pemberian ekstrak buah bit dan jus buah bit secara signifikan berpengaruh terhadap penurunan kadar kolesterol total. Pemberian ekstrak dan jus buah bit dapat menurunkan kadar kolesterol tikus putih.
PENYULUHAN TENTANG BAHAYA FORMALIN TERHADAP TUBUH DI DESA SIDODADI Linda Margata; Nurul Aini Siagian
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (83.456 KB) | DOI: 10.36656/jpmph.v2i1.611

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Food additives (BTM) especially additives are becoming increasingly significant in line with the advancement of innovation in the creation of engineered foods. One of the food additives permitted for use in food as indicated by Pastor Health Guidelines No. 722/Menkes/Per/IX/88 is an additive, where these additives can be described as food additives that can prevent or resist aging, fermentation or other food sources caused by microbial development. The use of additives in food should be appropriate, both type and dosage, but until now there is still a lot of work of additives that are prohibited for use in food and are not safe for welfare such as borax and formalin. Formalin is widely abused to protect food sources such as tofu and wet noodles. Formalin is really a fixing to protect bodies and organs and is extremely risky for wellbeing, in this manner in the Guideline of the Pastor of Wellbeing No. 722/Menkes/Per/IX/88 formalin is one of the fixings that are disallowed from being utilized as food added substances. Formalin ought not be utilized as a food additive, so there ought to be no buildup on food. The utilization of formaldehyde in food can cause harming in people with indications of trouble gulping, intense stomach torment, heaving, dying, circulatory issues and at high portions can bring about death. On the off chance that the formalin content in the body is high, it will respond artificially with practically all substances in the phone hence stifling cell capacity and causing cell demise bringing about body harming. Formalin harming can cause stomach bothering and hypersensitivities. Formalin also has carcinogens (cancerous) and mutagen properties (causing changes in cell function). In very high levels formalin can cause circulatory failure that boils down to death.
PENYULUHAN TENTANG PEMBERIAN OBAT RANITIDIN TERHADAP PASIEN GASTRITIS DI PUSKESMAS DELI TUA Linda Margata; Palas Tarigan
Jurnal Pengabdian Masyarakat Putri Hijau Vol 2 No 1 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.01 KB) | DOI: 10.36656/jpmph.v2i1.612

Abstract

Gastritis is the most widely recognized wellbeing problem in the wellbeing place. Gastritis is a condition of aggravation or draining in the gastric mucosa that can be intense, persistent, diffuse or nearby. The two most normal kinds of gastritis are intense shallow gastritis and atrophic gastritis. In daily existence, gastritis is whined of like awful desire for the upper midsection, for instance the stomach is in every case full, queasiness, feeling hot in the stomach, torment previously or subsequent to eating, etc (Oka, 2018). Pharmacological treatment to treat gastritis sickness can be indicative treatment used to hinder corrosive emission and increment mucosal protection from corrosive. Medications utilized, for example, different stomach settling agents that for the most part contain aluminum hydroxide, magnesium hydroxide or calcium carbonate and histamine receptor inhibitor drugs H stomach, for example, simetidin, ranitidine, nizatidin, and famotidin that adequately lessen the corrosive reaction (Oka, 2018). Ranitidine is a class of acid neutralizer drugs utilized for the treatment of stomach and duodenal ulcers, esophagitis reflux, neurotic hypersecrescence states (which are broadly utilized by the public Side effects of gastritis torment notwithstanding indigestion likewise cause manifestations like sickness, retching, shortcoming, bulging, feeling claustrophobic, craving diminished, pale face, internal heat level up, cool sweats, wooziness, continually burping and in more serious conditions, can upchuck blood (Shamsu, 2017). The Middle for General Wellbeing (Puskesmas) is a medical services office that coordinates general wellbeing endeavors and top notch individual wellbeing endeavors, focusing on promotive and preventive endeavors, to accomplish the most elevated level of general wellbeing in their workspace. Puskesmas has the assignment of executing wellbeing strategy to accomplish wellbeing improvement objectives in its workspace to help the acknowledgment of sound subdistricts (Permenkes, 2014).
PELATIHAN TENTANG MODIFIKASI PENANGANAN LIMBAH RS DI RSU SEMBIRING Martha Arizona; Linda Margata; Sarah Damayanti
Jurnal Pengabdian Masyarakat Putri Hijau Vol 1 No 2 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (256.199 KB) | DOI: 10.36656/jpmph.v1i2.682

Abstract

As one of the most important health service departments, the hospital always produces medical solid waste and non-medical solid waste in daily activities, especially in the inpatient department, specialist room section, general clinic section, specialist clinic room, dental clinic room, maternal and child care, laboratory clinics and pharmacies. Most medical solid waste contains substances that are highly contagious, infectious and dangerous. Therefore it must be managed properly, otherwise these wastes will become a new source of transmission for both the community around the hospital and for medical personnel in the hospital. The management and handling of hospital waste has special rules. By improving the handling and management of hospital waste, medical waste management, increasing knowledge of human resources in waste management, and its impacts can influence the creation of examples of healthy development from a healthy society by improving the quality of individual and community health. Hospital medical solid waste and the poor quality of the hospital environment are the causes of various health problems, therefore it is necessary to apply laws and regulations to monitor various environmental factors in accordance with hygienic principles of environmental cleanliness. This training and counseling proposes a medical solid waste management model at the Sembiring General Hospital to create a healthy environment around the hospital.
PELATIHAN SUMBER DAYA MANUSIA (SDM) DALAM PENINGKATAN MUTU LAYANAN DI RUMAH SAKIT UMUM GRANMED LUBUK PAKAM Linda Margata; Hariati Hariati; Jhan Saberlan
Jurnal Pengabdian Masyarakat Putri Hijau Vol 1 No 3 (2021): Jurnal Pengabdian Masyarakat Putri Hijau
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (379.892 KB) | DOI: 10.36656/jpmph.v1i3.716

Abstract

The hospital is a service organization that has a variety in terms of human resources, infrastructure and equipment used. Hospital human resources are hospital assets that are very valuable because human resources control all activities in the hospital. Human resource development is a lifelong process, therefore it is related to adult education and lifelong learning. This development is also a process of helping and sharing that leads to competence and satisfaction with both the process and the outcome. Human Resource Development (HR) is one of the important factors that affect performance. The importance of human resources needs to be realized by all levels of management because of the advancement of technology today, the human factor still plays an important role for the success of an organization. The performance quality of human resources (HR) is a measure of the success of health services that can demonstrate the accountability of service institutions within the framework of good clinical governance. This training is aimed at developing human resources which is carried out to increase knowledge and skills related to the quality of hospital services.
Formulasi Dan Evaluasi Sediaan Sabun Cair Ekstrak Ranting Patah Tulang (Euphorbia tirucalli Lin) Dan Uji Antibakteri Terhadap Escherichia colli Tahun 2021 Linda Margata; Linta Meliala
BEST Journal (Biology Education, Sains and Technology) Vol 4, No 2 (2021): September 2021
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v4i2.4261

Abstract

Ranting tulang yang patah (Euphorbia tirucali Lin) dapat dimanfaatkan sebagai obat yang memiliki aktivitas antibakteri. Kandungan kimia yang terkandung di dalamnya yang bersifat anti bakteri adalah alkaloid dan saponin. Penelitian ini bertujuan untuk memformulasi sediaan sabun cuci tangan dengan ekstrak etanol ranting patah tulang dan menguji aktivitas antibakteri dengan konsentrasi 5%, 10% dan 15% terhadap pertumbuhan bakteri Escherichia coli. Formulasi sabun cuci tangan dibuat dalam 3 formula dengan konsentrasi 5%, 10% dan 15%. Metode penelitian pengujian aktivitas antibakteri terhadap Escherichia coli dilakukan dengan metode difusi cakram. Hasil penelitian ranting patah tulang mengandung senyawa saponin. Hasil karakteristik simplisia yang diperoleh adalah kadar air 7,07%, ekstrak larut air 29,28%, ekstrak larut etanol 3,034%, kadar abu total 5,52% dan 0,67%. Hasil aktivitas antibakteri sabun cuci tangan dengan ekstrak etanol ranting patahan yang diperoleh mampu menghambat pertumbuhan bakteri Esherichia coli dengan konsentrasi 5%, 10% dan 15% dengan kategori zona hambat sedang. Ekstrak etanolik ranting patahan memiliki aktivitas antibakteri terhadap pertumbuhan bakteri Escherichia coli dan paling efektif dalam menghambat pertumbuhan Escherichia coli dengan rata-rata diameter zona hambat terkuat pada 15% : 7,83 mm bakteri Escherichia coli dibandingkan konsentrasi lainnya. , yaitu 10%: 6,26 mm dan konsentrasi 5%: 4,25 mm