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Desain Primer PCR Sebagai Biomarker COVID-19 Strain Terbaru Yang Di Identifikasi Di Januari 2021 Muhammad Azhari Herli; Dewi Gulyla Hari; Ayu Rahmawati
Sistem Informasi Vol 11 No 2 (2021): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v11i2.3645

Abstract

Coronavirus disease 2019 (COVID-19) is a contagious disease caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS CoV-2). The disease first spread in Wuhan, Hubei Province, China in December 2019. SARS-CoV-2 is highly contagious and has grown rapidly around the world since its discovery. Until January 2021, a total of 101,406,059 confirmed cases of SARS-CoV-2 infection worldwide with a death toll of 2,191,898 and still growing. Diagnosis of COVID-19 is carried out in two common ways, namely a rapid test and PCR (polymerase chain reaction). This study aims to design a PCR primer for the latest COVID-19 strain isolated in January 2021 with the insilico method (computer simulation) so that the primer used as a COVID-19 biomarker is fast and accurate. The results of this study obtained 10 of the best primers from the latest COVID-19 strains with codes MW454767, MW454771, MW460582, MW454660 which were identified on 11 Jan 2021.
Pemanfaatan “Coding Danker” Terhadap Peningkatan Produksi ASI Ibu Menyusui Nova Yulita; Sarah Fitria; Jumiati Jumiati; Nevy Susianty; Siti Nurkhasanah; M. Azhari Herli Saptadi Putra; Ayu Rahmawati; Maswarni Maswarni; Reni Ardila; Rahmi Nawiti; Ayuni Septiani; Nazla Anugerah Hendri
JATI EMAS (Jurnal Aplikasi Teknik dan Pengabdian Masyarakat) Vol 5 No 3 (2021): Jati Emas (Jurnal Aplikasi Teknik dan Pengabdian Masyarakat)
Publisher : Dewan Pimpinan Daerah (DPD) Perkumpulan Dosen Indonesia Semesta (DIS) Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36339/je.v5i3.503

Abstract

The practice of breastfeeding is one way to optimize the health and development of children. Exclusive breastfeeding for infants 0-6 months without providing complementary foods/substitutes for breast milk. Exclusive breastfeeding problems can be caused by breast milk that does not come out after childbirth, lack of milk production, the inability of the baby to suck, abnormal conditions of the mother's nipples, working mothers, and lack of health information. Health problems that often occur in breastfeeding mothers are reduced milk production, which will later affect breastfeeding status so that it can be a risk factor for stunting. One way to increase the volume of breast milk is to provide Moringa leaf extract as an ingredient to be processed into alternative food products, namely "Coding Danker". This community service activity was carried out three times, namely exclusive breastfeeding and stunting counseling, processing alternative food products from Moringa leaves, providing food products to the community, breastfeeding mothers and monitoring evaluations and interventions from providing Coding Danker to breastfeeding mothers. This activity is aimed at increasing the knowledge and skills of PKK mothers in RW 7 Sialang Munggu Village in making pastries based on local wisdom, namely cookies with Moringa leaf extract. Community service participants were given material by showing videos on how to make these products. The outputs of this community service are one scientific article, one article in print/electronic mass media, activity videos and community service reports.
Uji Aktivitas Antioksidan Fraksi Etil Asetat dan Fraksi Etanol Limbah Ketapang (Terminalia catappa) dengan Metode DPPH Hafifah Jasman; Ayu Rahmawati; M. Azhari Herli
Jurnal Farmasi Sains dan Terapan Vol 8, No 1 (2021): Februari
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v8i1.2825

Abstract

Ketapang (Terminalia catappa) diketahui mengandung flavanoid yang dapat menangkal radikal bebas karena adanya gugus kromofor (ikatan rangkap terkonjugasi). Flavonoid mempunyai kemampuan untuk menyumbangkan atom hidrogen kepada senyawa radikal bebas. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan fraksi etil asetat dan fraksi etanol Limbah Ketapang (Terminalia catappa) yang diperoleh dengan metode maserasi menggunakan pelarut etanol 96%. Aktivitas antioksidan fraksi etil asetat dan fraksi etanol Limbah Ketapang (Terminalia catappa) ditentukan dengan mengukur % inhibisi dan nilai IC50 (inhibitory concentration 50%) menggunakan spektrofotometer UV. Hasil penelitian menunjukkan fraksi etil asetat limbah ketapang (Terminalia catappa) memiliki aktivitas antioksidan sangat kuat dengan nilai IC50 -28,521 ppm. Sedangkan fraksi etanol limbah ketapang (Terminalia catappa) memiliki aktivitas antioksidan yang kuat dengan nilai IC50 32,53 ppm. Pembanding kuersetin memiliki aktivitas antioksidan kuat dengan nilai IC50 17,68 ppm.