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Rusdiati Helmidanora
Sekolah Tinggi Ilmu Kesehatan Samarinda
Agriculture, Biological Sciences & Forestry Humanities Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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EFEKTIVITAS EKSTRAK ETANOL DAUN SERUNAI (Chromolaena odorata L.) SEBAGAI ANALGETIKA Helmidanora, Rusdiati; Chairunnisa, Chairunnisa; Sukawaty, Yullia
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3, No 2 (2018)
Publisher : Akademi Farmasi ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (8.262 KB)

Abstract

Daun serunai (Chromolaena odorata L) mengandung senyawa utama yaitu senyawa flavonoid, saponin, triterpen, steroid dan tanin. Diketahui daun serunai memiliki aktivitas farmakologi antelmintik, antimalaria, analgesik, antiinflamasi, antipiretik, antispasmodik, antimikroba, antifungi dan diuretik. Efek analgetika daun serunai berasal dari flavonoid yang terkandung di dalamnya. Metode penyarian daun serunai dilakukan secara maserasi menggunakan alkohol 70%, bertujuan untuk mengetahui efektivitas ekstrak daun serunai sebagai analgetik pada mencit putih jantan. Penelitian ini bersifat eksperimental dengan metode pengumpulan sampel secara purposive sampling, menggunakan hewan uji mencit jantan putih yang terbagi menjadi 5 kelompok (kontol positif (kalium diklofenak), kontrol negatif (Na-CMC 0,5%), dosis (50 mg/kg BB, 100 mg/kg BB, dan  200 mg/kg BB), diinduksi nyeri dengan menggunakan asam asetat 0,5%. Daya analgetik dihitung dengan menghitung jumlah geliat mencit selama 1 jam. Data yang diperoleh dianalisis menggunakan uji kruskal wallis. Ekstrak etanol daun serunai memiliki potensi efektivitas sebagai daya analgetik terhadap mencit putih jantan (p 0,043 > 0,05) dengan persentase daya analgetik pada dosis 50 mg/kg BB (28,5%), dosis 100 mg/kg BB (58,8%), dosis  200 mg/kg BB (67,3%).
DRPs (DRUG RELATED PROBLEMS) PADA PENDERITA DIABETES MELLITUS DENGAN KOMPLIKASI GAGAL GINJAL DI RUMAH SAKIT UMUM DAERAH ‘X’ DI SAMARINDA PERIODE OKTOBER-DESEMBER 2016 Helmidanora, Rusdiati; Reza, Muhammad; Sukawaty, Yullia
Jurnal Ilmiah Manuntung Vol 4 No 2 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

Drug Related Problems (DRPs) is an unexpected event from the patient's experience because drug therapy can interfere with the success of healing. Patients with chronic disease for a long time have a chance of developing DRP. One chronic disease is diabetes mellitus which is a metabolic disorder due to lack of insulin production produced by the pancreas gland. Diabetic nephropathy is a microvascular complication that often occurs in type 1 and type 2 diabetes, due to high blood sugar levels that can cause kidney structure to change and impaired function. The aim of this study was to determine DRP in patients with diabetes with kidney failure. Research conducted was non-experimental research with data collection retrospectively. The data were analyzed by using standard reference books, Drug Information Handbooks. Based on the results of the study found DRPs in patients with DM with kidney failure in the inpatient installation of RSUD 'X' Samarinda in the period October-December 2016 who needed drugs but did not receive it (24%), received drugs without appropriate indications (11%), received wrong drugs (3%), dose was too low (0%), dose was too high (5%), the patient has ADR (13%), and compliance (0%).
EFEK HIPOTENSIF DARI ACEi DAN ARB PADA PASIEN DIABETES MELLITUS DAN HIPERTENSI DI RSUD. ABDUL WAHAB SYAHRANIE SAMARINDA Helmidanora, Rusdiati; Sentat, Triswanto
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

More than two-thirds of patients with type 2 diabetes also experience hypertension whose development coincides with hyperglycemia, where each disease has a tendency to influence the increased risk of other diseases. Sundry new guidelines, such as the National Joint Committee 8, the American Diabetes Association recommend blood pressure targets in the diabetic population of <140/90 mmHg to reduce cardiovascular risk and prevent the progression of nephropathy. This study aims to determine whether there is a difference in achieving blood pressure target < 140/90 mmHg according to Join National Committee 8 between ACEi and ARB in patients with type 2 diabetes with hypertension. This research was conducted using a retrospective at internist clinic of Abdul Wahab Syahranie hospital, by taking secondary data from the medical record from blood pressure o 49 outpatients received a single antihypertensive either drug ACEi 29 people or ARB 34 people. This study showed that the achievement of target blood pressure by <140/90 mmHg (JNC 8 guideline) between ACEi 7 (28%) and ARB 5 (20,8%) group and it can be concluded that between ACEi and ARB drugs(P=0.5) there was no differsignificantly in achievement blood pressure target on type 2 diabetes with hypertension.
Profil Peresepan Obat Peyakit Diare pada Pasien Rawat Inap Anak di RSU Dr. Kanujoso Djatiwibowo Balikpapan Yullia Sukawaty; Rusdiati Helmidanora; Fitri Handayani
Jurnal Ilmu Kesehatan Vol 5 No 2 (2017): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v5i2.63

Abstract

Diarrhea is one of the leading causes of death especially in children. Approximately 10% of cases of diarrhea in children under five years old (toddlers) worldwide are bloody diarrhea or dysentery.The purpose of this study was to determine profile of the diarrhea prescribing of children inpatients at hospital Dr. Kanudjoso Djatiwibowo Balikpapan period October to December 2015.This research was conducted by non experimental retrospectively method with purposive sampling and analyzed descriptively using microsoft excel.Profile of the diarrhea prescribing of children inpatients at hospital Dr. Kanudjoso Djatiwibowo Balikpapan encompasses the use of the single most antibiotic ceftriaxone 24%, the most commonly used combination antibiotic, ampicillin combination with chloramphenicol 12%, rehydration therapy widely used lactate ringer 38%, supplement therapy widely used zinc 90%.Prescribing medication for diarrheal disease of inpatients at hospital Dr. Kanudjoso Djatiwibowo Balikapapan has been in accordance with the procedure of diarrhea treatment of Ministry of Health RI (MOH RI 2011) five steps to solve diarrhea.
EFEKTIVITAS EKSTRAK ETANOL DAUN SERUNAI (Chromolaena odorata L.) SEBAGAI ANALGETIKA Rusdiati Helmidanora; Chairunnisa Chairunnisa; Yullia Sukawaty
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 2 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.904 KB) | DOI: 10.36387/jiis.v3i2.187

Abstract

Daun serunai (Chromolaena odorata L) mengandung senyawa utama yaitu senyawa flavonoid, saponin, triterpen, steroid dan tanin. Diketahui daun serunai memiliki aktivitas farmakologi antelmintik, antimalaria, analgesik, antiinflamasi, antipiretik, antispasmodik, antimikroba, antifungi dan diuretik. Efek analgetika daun serunai berasal dari flavonoid yang terkandung di dalamnya. Metode penyarian daun serunai dilakukan secara maserasi menggunakan alkohol 70%, bertujuan untuk mengetahui efektivitas ekstrak daun serunai sebagai analgetik pada mencit putih jantan. Penelitian ini bersifat eksperimental dengan metode pengumpulan sampel secara purposive sampling, menggunakan hewan uji mencit jantan putih yang terbagi menjadi 5 kelompok (kontol positif (kalium diklofenak), kontrol negatif (Na-CMC 0,5%), dosis (50 mg/kg BB, 100 mg/kg BB, dan  200 mg/kg BB), diinduksi nyeri dengan menggunakan asam asetat 0,5%. Daya analgetik dihitung dengan menghitung jumlah geliat mencit selama 1 jam. Data yang diperoleh dianalisis menggunakan uji kruskal wallis. Ekstrak etanol daun serunai memiliki potensi efektivitas sebagai daya analgetik terhadap mencit putih jantan (p 0,043 > 0,05) dengan persentase daya analgetik pada dosis 50 mg/kg BB (28,5%), dosis 100 mg/kg BB (58,8%), dosis  200 mg/kg BB (67,3%).
PENENTUAN AKTIVITAS TABIR SURYA DAN ANTIOKSIDAN EKSTRAK ETANOL BENALU (Henslowia frutescens) INANG JERUK BALI SECARA IN VITRO Henny Nurhasnawati; Rusdiati Helmidanora; Yullia Sukawaty; Andri Priyoherianto; Elly Purwati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 1 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.661 KB) | DOI: 10.36387/jiis.v6i1.647

Abstract

Henslowia frutescens is a semi-parasitic plant, although considered harmful, it has medicinal and cosmetic potential. This plant has secondary metabolite compounds, namely phenolic compounds, flavonoids, saponins, tannins, and steroids which have high antioxidant activity. The purpose of this study was to determine the sunscreen activity of the ethanol extract of Henslowia frutescens based on the in vitro SPF (Sun Protecting Factor) value and to determine its antioxidant activity. The research stages included sampling, sampling, maceration extraction with 95% ethanol, yield calculation, phytochemical screening, sunscreen activity test based on SPF value, and antioxidant activity test. Data analysis was carried out descriptively based on the measurement results processed according to the calculation formula. The results showed that the sunscreen activity of the ethanol extract of Henslowia frutescens based on the in vitro SPF value was 14.57 - 25.20 with moderate protection category. The antioxidant activity of the ethanol extract of Henslowia frutescens showed a very strong category with an IC value of 22.82 ± 1.33.
Pelatihan Pembuatan Hand Sanitizer di Kantor Dinas Perindustrian Kota Samarinda Risa Supriningrum; Hayatus Sa’adah; Rusdiati Helmidanora
Jurnal Abdimas Mahakam Vol. 5 No. 01 (2021): Januari
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

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Abstract

Sejak terjadinya pandemi covid 19 ketersediaan hand sanitizer di Indonesia menjadi sangat langka di pasaran, dikarenakan banyak orang yang membeli barang tersebut secara berlebihan. Pemerintah menghimbau kepada masyarakat untuk selalu menjaga kebersihan tangan dengan rajin mencuci tangan menggunakan sabun atau menggunakan hand sanitizer sebagai salah satu upaya mencegah penularan covid 19. Pembersih tangan (hand sanitizer) memiliki kemampuan menghambat hingga membunuh bakteri. Tujuan dilakukannya pengabdian masyarakat ini adalah memberikan pelatihan kepada masyarakat cara membuat hand sanitizer dari bahan sintetis dan bahan alam. Formula hand sanitizer dari bahan sintetis berupa alkohol 96%, hydrogen peroksida, gliserin dan aquades. Sedangkan formula hand sanitizer dari bahan alam berupa daun sirih, jeruk nipis dan aquades. Kegiatan ini merupakan kerjasama antara Dinas Perindustrian, Perdagangan, Koperasi, Usaha Kecil dan Menengah Provinsi Kalimantan Timur dengan Sekolah Tinggi Ilmu Kesehatan Samarinda. Peserta pada kegiatan ini adalah perwakilan warga Kelurahan Karang Asam Ilir, Kelurahan Sempaja Utara dan Kelurahan Sungai Kapih. Metode yang digunakan pada pengabdian masyarakat meliputi ceramah tentang pentingnya menjaga kebersihan tangan, pengertian hand sanitizer, uraian bahan yang digunakan, dilanjutkan demonstrasi dan bimbingan. Kegiatan ini didanai oleh Desperidagkop UKM Provinsi Kalimantan Timur. Harapan dengan dilaksanakan pelatihan ini ialah masyarakat dari kelurahan yang menjadi peserta lebih peduli dengan kebersihan dan dapat memenuhi kebutuhan hand sanitizer untuk keluarga dan masyarakat sekitarnya.
Profil Kepatuhan Minum Obat Pada Pasien Hipertensi Di Puskesmas Muara Wis: Profil Kepatuhan Minum Obat Pada Pasien Hipertensi Di Puskesmas Muara Wis Husnul Warnidah; Rusdiati Helmidanora; Triswanto Sentat; Yullia Sukawaty; Endah Handayani
Ahmar Metastasis Health Journal Vol. 1 No. 3 (2021): Ahmar Metastasis Health Journal
Publisher : Yayasan Ahmad Mansyur Nasirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (858.814 KB) | DOI: 10.53770/amhj.v1i3.67

Abstract

Introduction: Patient compliance has an impact on treatment success. Poor adherence impedes hypertensive patients' ability to control their blood pressure; patients frequently fail to take the prescribed medication. This study aims to assess medication adherence in hypertensive patients at the Muara Wis Health Center. The MMAS-8 questionnaire and the calculation of the number of medicines were used to collect data (pill count). Patients with hypertension at the Muara Wis Health Center were eligible to participate in this study if they had been on medication for at least twelve months, had no complications, and provided informed consent. The descriptive analysis method was used to analyze the data. According to the questionnaire data, the low adherence level is 53.33 percent, moderate adherence is 33.33 percent, and high adherence is 13.33 percent. According to the pill count method, 50.00 percent of patients have low adherence, 30.00 percent have moderate adherence, and 20.00 percent have high adherence. The Spearman rank correlation test revealed a relationship between the questionnaire and pill count methods. The result shows that the patient's adherence to the Muara Wis Health Center is low. It is suggested that the Muara Wis Health Center is more active in counseling patients to increase patient motivation. Pendahuluan:  Kepatuhan pasien berpengaruh terhadap keberhasilan suatu pengobatan. Kegagalan pasien hipertensi mencapai target penurunan darah seringkali disebabkan pasien tidak meminum obat yang diresepkan. Penelitian ini bertujuan untuk mengetahui kepatuhan minum obat pada pasien hipertensi di Puskesmas Muara Wis. Penelitian dilakukan dengan metode Cohort study menggunakan alat kuesioner MMAS-8 dan penghitungan jumlah obat yang belum diminum pasien (pill count). Sampel yang dipilih adalah pasien hipertensi di Puskesmas Muara Wis, telah meminum obat antipertensi minimal 12 bulan, tidak memiliki penyakit komplikasi, dan bersedia menjadi responden. Data dianalisis secara deskriptif. Hasil penelitian menunjukkan pasien memiliki tingkat kepatuhan minum obat yang rendah 53,33%, kepatuhan sedang 33,33%, kepatuhan tinggi 13,33%. Berdasarkan metode pill count, 50,00% pasien memiliki tingkat kepatuhan rendah, 30,00% tingkat kepatuhan sedang, dan 20,00% tingkat kepatuhan tinggi. Uji korelasi spearman rank menunjukan bahwa bahwa ada hubungan antara antara tingkat kepatuhan pasien dari metode kuesioner dengan hasil perhitungan pill count. Hal ini menunjukkan bahwa kepatuhan pasien meminum obat antihipertensi di puskesmas Muara Wis masih rendah. Disarankan Puskesmas Muara Wis lebih aktif melakukan konseling kepada pasien untuk meningkatkan motivasi pasien.
PELATIHAN PEMANFAATAN LIMBAH RUMAH TANGGA DI KELURAHAN SIDODAMAI KOTA SAMARINDA MENJADI PUPUK KOMPOS Husnul Warnida; Yullia Sukawaty; Rusdiati Helmidanora
Jurnal Abdi Masyarakat Kita Vol 1 No 2 (2021): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1860.579 KB) | DOI: 10.33759/asta.v1i2.164

Abstract

Waste is a material that is no longer used so that it is then thrown away. All community activities generate waste, so the volume of waste continues to increase. The community is responsible for processing waste so that it does not have a negative impact on the environment. Waste is one of the factors that play a role in flooding in Samarinda. Household waste in the form of vegetable and fruit peels can be processed into compost. Compost improves soil structure by increasing the organic matter content of the soil and will increase the soil's ability to retain soil water content. The process of making compost is quite easy and can be done independently on a household scale. The training on the use of household waste into compost was addressed to residents of RT.6 RW.2 Jalan Jelawat, Sidodamai, Samarinda Ilir District. This activity aims to provide training on household organic waste management to the people, so that it is not wasted and keeps the environment clean. The expected long-term impacts are the reduction in the volume of municipal waste, reducing the frequency of floods, and improving the community's economy, through the production of compost and agricultural products. The training was held on May 29, 2021 by STIKSAM lecturers and students, and was attended by members of PKK RT.06. The training was conducted using lecture and demonstrated methods. The trainees are interested in making compost and will use compost for ornamental plants and vegetables planted in their yards.
FORMULASI SEDIAAN SPRAY GEL EKSTRAK DAUN BANDOTAN (Ageratum conyzoides.L) SEBAGAI ANTINYAMUK Anastasia Reni Mangalik; Rusdiati Helmidanora; Hayatus Sa'adah
Jurnal Riset Kefarmasian Indonesia Vol 5 No 2 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i2.364

Abstract

There are many types of mosquitoes that cause disease in humans, one of which is the Anopheles mosquito that spreads malaria. Bandotan plants are used to treat colic, flu, fever, antidiarrheal, diarrhoea. The purpose of this study was to determine the concentration of bandotan (Ageratum conyzoides.L) leaf extract that provides the best physical properties and anti-mosquito activity in spray gel preparations. The research method conducted was experimental. The object studied was the formulation of bandotan leaf preparation as an antinyamite. The research stages include plant determination, sample collection, simplisia preparation, extraction using maceration method with 70% ethanol solvent, identification of secondary metabolite compounds, preparation of spray gel formula, and preparation evaluation. Bandotan leaf extract was formulated into anti-mosquito spray gel preparations with concentration variants of 10%, 15%, 20%, and using positive control of X brand anti-mosquito spray as a comparison. The preparation testing included organoleptic test, homogeneity test, pH test, viscosity test, and mosquito repellency test. The results of data collection were analysed statistically. A good preparation formula is found in the negative control formula because it has a stable consistency and pH. The results showed that the ethanol extract of bandotan leaves was not significantly different from the organoleptic test, homogeneity test, viscosity test, and pH test. The greatest mosquito repellency was at a concentration of 20% which was 66.33%, at concentrations of 10% and 15% had an average anti-mosquito activity of 22.83% and 57.83% respectively for the positive control with brand X of 99.30%.
Co-Authors Anastasia Reni Mangalik Andri Priyoherianto Chairunnisa Chairunnisa Chairunnisa Chairunnisa Elly Purwati Endah Handayani Fitri Handayani Hayatus Sa'adah Hayatus Sa’adah Henny Nurhasnawati Husnul Warnida Husnul Warnidah Is alukal Fauziah A.A Muhammad Reza Risa Supriningrum Siti Jubaidah Sukawaty, Yullia Sukawaty, Yullia Yullia Sukawaty Yullia Sukawaty Yullia Sukawaty Yullia Sukawaty Yullia Sukawaty