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Hubungan Obesitas dan Hipertrigliseridemia dengan Risiko Perlemakan Hati pada Pasien di Makassar Kasim, Syaharuddin; Arief, Mansur; Sulaeman, Agus; Widodo, Joko
Indonesian Journal of Clinical Pharmacy Vol 1, No 4 (2012)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (628.406 KB)

Abstract

Perlemakan hati terjadi akibat lipolisis berlebihan dari jaringan lemak dan peningkatan suplai asam lemak bebas ke hati. Derajat keparahan perlemakan hati berkorelasi dengan peningkatan berat badan. Penelitian ini bertujuan untuk menemukan hubungan antara obesitas, trigliserida, obesitas dan hipertrigliseridemia terhadap risiko terjadinya perlemakan hati. Penelitian cross sectional menggunakan data retrospektif yang diambil dari pasien check up di Laboratorium Klinik Prodia Makassar selama tahun 2006. Diagnosis perlemakan hati melalui pemeriksaan ultrasonografi, obesitas ditentukan dari indeks massa tubuh, dan trigliserida diukur dengan metode enzimatik kolorimetri. Dari 204 pasien check up, 67 pasien (32,8%) mengalami perlemakan hati. Pada pasien dengan perlemakan hati sebanyak 95,5% mengalami obesitas, 67,2% hipertrigliseridemia, dan 32,8% trigliserida normal. Terdapat hubungan bermakna antara obesitas (risiko relatif (RR)=18,7; 95% C.I 5,6–62,4; p=0,001), obesitas disertai hipertrigliseridemia (RR=5,1; 95% C.I 2,7–9,5; p<0,001) dengan perlemakan hati. Didapatkan hubungan bermakna antara perlemakan hati dengan obesitas. Trigliserida tidak berhubungan langsung tetapi hipertrigliseridemia disertai obesitas berhubungan bermakna dengan kejadian perlemakan.Kata kunci: Obesitas, trigliserida, hipertrigliseridemia, perlemakan hati Relationship between Obesity and Hypertriglyceridemia on Fatty Liver in Patients at MakassarAbstractFatty liver is caused by a failure of normal hepatic fat metabolism due to a dysfunction of either within the hepatocytes. The degree of fatty liver is correlating to the increase of body weight. The aim of this study is to investigate any specific relationship between fatty liver and obesity as well as hypertriglyceridemia.This is a cross sectional study by using the retrospective data which is obtained from medical check up at Prodia clinical laboratory during 2006, fatty liver is diagnosed by using ultrasonography,obesity on body mass index (BMI), and triglyceride level by enzymatic colorimetric method.In 204 subjects of medical check up subjects were analyzed. Fatty liver has been found in 67 subjects (32.8%),95.5% of subjects with obesity, 32.8 subjects with normal triglyceride and 67.2% subjects with hypertriglyceridemia. There are significant relationship of obesity (relative risk(RR)=18.7; 95% C.I 5.6–62.4;p=0.001), obesity and hypertrigliseridemia (RR=5.1; 95% C.I 2.7–9.5; p<0.001) with fatty liver. Thereare a significant relationship of fatty liver and as well as obesity. Triglyceride is not contributing directlyto fatty liver but hypertriglyceridemia with obesity have significant relationship with fatty liver.Key words: Obesity, triglyceride, hypertriglyceridemia, fatty liver
Levels of Adiponectin and Soluble Tumor Necrosis Factor-α Receptor 2 (sNFαR2) in Obese Males with or without Fatty Liver Sulaeman, Agus; Wahid, Syarifuddin; Sulaiman, Ali; Lawrence, Gatot Susilo
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 1, April 2011
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.24871/12120111-7

Abstract

Background: Increased lipolysis in obese patients will cause elevated free-fatty acid level leading to insulin resistance. There are varied inflammatory cytokines (sTNFαR2) and anti-inflammatory cytokines (adiponectin) in obese patients, with and without fatty liver (FL). The aim of this study was to determine sTNFαR2 and adiponectin levels in obese patients with and without fatty liver. Method: This study was an observational study with cross-sectional approach, which was conducted between September 2008 and August 2009. The patients were 94 obese male with waist circumference ≥ 90 cm based on criteria of the International Diabetes Federation. Fatty liver was detected by ultrasonography; while adiponectin and sTNFαR2 levels in blood were analyzed by using ELISA Method and blood examination at the clinical laboratory. Results: Levels of adiponectin and sTNFαR2 were different between obese patients with and without FL. The adiponectin level was 3.10 ± 1.14 in patients with FL and was 3.52 ± 1.07 in patients without FL; while the sTNFαR2 were 23.92 ± 6.00 (FL) and 20.61 ± 5.29 (without FL). In patients with low adiponectin level (< 3.33 µ g/L) and high sTNFαR2 level (> 21.78 pg/dL), there was relatively higher occurrence of fatty liver compared to the other patients. Conclusion: Obese patients with fatty liver have higher sTNFαR2 level than patients without fatty liver. Moreover, obese patients with fatty liver have lower adiponectin level compared to patients without fatty liver. Patients with low adiponectin level and high sTNFαR2 level have higher incidence of fatty liver than subjects with high adiponectin level and low sTNFαR2 level. Keywords: adiponectin, soluble tumor necrosis factor α receptor 2 (sTNFαR2), obese, fatty liver
POTENSI RIMPANG BANGLE HANTU (Zingiber ottensii Val.) SEBAGAI ANTIHIPERGLIKEMIA PADA MODEL HEWAN DIABETES YANG DIINDUKSI FRUKTOSA Hasimun, Patonah; Sulaeman, Agus; Dewi, Nova Freena
JURNAL FARMASI GALENIKA Vol 4 No Edisi Khus (2017): Jurnal Farmasi Galenika Volume 4 Edisi Khusus SemNas Tanaman Obat Indon
Publisher : Sekolah Tinggi Farmasi Bandung

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Abstract

Latar belakang : Diabetes melitus (DM) dicirikan dengan intoleransi glukosa yang menghasilkan terjadinya hiperglikemia dan gangguan dalam metabolisme lipid dan protein. DM tipe 2 adalah jenis DM yang paling sering dijumpai dan pada umumnya diawali oleh gangguan fungsi insulin (resistensi insulin) yang mana selain dapat meningkatkan kadar glukosa darah juga dapat meningkatkan kadar trigliserida. Penelitian ini dilakukan untuk mengetahui aktivitas ekstrak bangle hantu (Zingiber ottensii Val.) sebagai antihiperglikemia dan dosis efektif ekstrak rimpang bangle hantu (Zingiber ottensii Val.) yang dapat menurunkan kadar glukosa darah pada model hewan yang diinduksi fruktosa Metode&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; : Penelitian ini menggunakan desain true experimental in vivo pada hewan coba tikus yang diinduksi dengan fruktosa dan propiltiourasil (PTU). Hewan coba dibagi menjadi 6 kelompok (n = 6), yaitu kelompok normal, kelompok pembanding, kelompok induksi dan 3 kelompok ekstrak dengan dosis 50 mg/kg BB, 100 mg/kg BB dan 150 mg/kg BB. Hasil : Terjadi penurunan kadar glukosa darah tikus selama test toleransi glukosa yang dilakukan pada hari ke 8, 15, dan 22 serta kadar trigliserida yang diuji pada hari ke 22. Kesimpulan : Ekstrak rimpang bangle hantu (Zingiber ottensii Val.)&nbsp; memiliki potensi sebagai antihiperglikemia terhadap model hewan diabetes yang diinduksi fruktosa dan memiliki aktivitas maksimal sebagai antihiperglikemia secara in vivo pada dosis 100 mg/kg BB.
PENINGKATAN PENGETAHUAN DAN MINAT MASYARAKAT TERHADAP PRODUK HERBAL DALAM MENGHADAPI COVID-19 Marliani, Lia; Fatin, Mia Nisrina Anbar; Kusriani, R. Herni; Sulaeman, Agus; Kaniawati, Marita
Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ Vol 8 No 2 (2021): Mei
Publisher : Lembaga Penelitian, Penerbitan dan Pengabdian Masyarakat (LP3M) UNSIQ

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32699/ppkm.v8i2.1533

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Dalam masa Adaptasi Kebiasaan Baru, angka kejadian COVID-19 di Jawa Barat masih meningkat. Kasus terkonfirmasi yang masih meningkat menuntut masyarakat harus siap untuk mengendalikan dan mencegah infeksi semakin menyebar dengan meningkatkan sistem daya tahan tubuh. Pengetahuan masyarakat akan hal ini terutama dalam memanfaatkan sumber daya yang ada di sekitar keluarga sebagai suplemen untuk meningkatkan sistem imun masih belum optimal. Tujuan dari pengabdian masyarakat ini adalah memberikan edukasi mengenai sistem imunitas dan pemanfaatan bahan alam untuk meningkatkan sistem imun yang dilanjutkan dengan tutorial pembuatan produk herbal dari TOGA untuk meningkatkan sistem imunitas tubuh. Metode pelaksanaan kegiatan adalah melalui metode daring dimana kuisioner, edukasi, penyebaran informasi, dan pemberian tutorial dilakukan melalui platform Youtube, WhatsApp Grup, dan Instagram. Tahapan kegiatan meliputi identifikasi kebutuhan masyarakat, Perancangan kegiatan, survei pengetahuan awal masyarakat, pemberian edukasi dan tutorial melalui poster edukasi dan video tutorial, Pemberian masker, bahan baku, dan contoh produk herbal jadi siap konsumsi untuk bahan praktek simulasi oleh tim Penggerak PKK dan Evaluasi kegiatan dengan mengukur peningkatan pengetahuan dan minat masyarakat. Hasil dari kegiatan ini adalah terdapat peningkatan pengetahuan dan minat masyarakat dalam menghadapi COVID-19 dimana sebelum adanya edukasi, tingkat pengetahuan terbanyak adalah tingkat pengetahuan yang cukup. Setelah adanya edukasi terjadi peningkatan pengetahuan yaitu menjadi baik (75%) dan tidak ada lagi yang memiliki tingkat pengetahuan kurang. Minat warga untuk mengolah dan menggunakan produk atau sediaan herbal siap saji juga meningkat.
The Effect of w/c Ratio of Compacted Bored Pile to Friction Resistance of Unjani Clay Sulaeman, Agus; Muhamad Agung; Regi Fasya Septrian
Jurnal Teknik: Media Pengembangan Ilmu dan Aplikasi Teknik Vol 20 No 1 (2021): Jurnal Teknik - Media Pengembangan Ilmu dan Aplikasi Teknik
Publisher : Fakultas Teknik - Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jt.vol20no1.409

Abstract

The small scale physical model of drum type was set-up to obtain the effect of water cement ratio (w/c) to pile capacity and original soil. The simulation of the process of providing bored piles model, soils model, installation and tests (pile loading tests and direct shear tests) under different water cement ratio of mortar and various moisture content of clay were done. The results reveal that the higher water content of original clay the bigger friction resistance, α value as clay soil is softer and the optimum w/c-ratio (w/c = 0,4) provides more pile capacity. It is understandable that water plays an important role, contributes to the change of surrounding clay properties. The improvement of Su ( % increase) due to compaction of concrete in bored pile, migration of moisture and reaction with surrounding clay leads to take benefit of design and construction of bored pile in clay soil for the sake of efficiency and stability.
AN ECLECTIC APPROACH IN SYLLABUS DESIGN: A PRELIMINARY STUDY OF ONE-TO-ONE TEACHING INDONESIAN FOR SPEAKERS OF OTHER LANGUAGES Sundari, Hanna; Miranti, Ira; Sulaeman, Agus
Jurnal Pendidikan Bahasa dan Sastra Vol 20, No 2 (2020): OKTOBER 2020
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/bs_jpbsp.v20i2.33060

Abstract

The industry of BIPA (Indonesian for foreigners) has extensively increased both at home and overseas. As a result, its teaching needs to be well-planned and organized. Supported by the view that no best method for all, eclecticism can be selected as approach to teaching. This paper is purposed to describe the initial stages of syllabus design particularly for one-to-one teaching Indonesian using eclectic approach. Carried out by descriptive research as part of research and development design, non-structured interview, observation, and open-ended questionnaire were as instruments to collect the information about learner and previous teaching process. Using a framework of syllabus development by Graves, need analysis and first draft syllabus were taken place. The need analysis reveals the learner characteristics and need of learning, such as age, gender, motivation and expectation. Moreover, grounded by the result of gathered information from need analysis, the developed syllabus is then a combination of task-based approach of language learning and structural-based syllabus which embraces accuracy and fluency as well as covers the features of eclectic system. 
Interferensi Morfologi dalam Karangan Narasi Mahasiswa Thailand Semester IV Pendidikan Bahasa dan Sastra Indonesia FKIP Universitas Muhammadiyah Tangerang Mutoharoh Mutoharoh; Agus Sulaeman; Goziyah Goziyah
Silampari Bisa: Jurnal Penelitian Pendidikan Bahasa Indonesia, Daerah, dan Asing Vol 1 No 1 (2018): Silampari Bisa: Jurnal Penelitian Pendidikan Bahasa Indonesia, Daerah, dan Asing
Publisher : LP4MK STKIP PGRI Lubuklinggau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (566.88 KB) | DOI: 10.31540/silamparibisa.v1i1.10

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Tujuan penelitian ini untuk mendeskripsikan bentuk-bentuk interferensi morfologi bahasa Melayu Thailand terhadap bahasa Indonesia dalam karangan narasi mahasiswa Thailand semester 4 yang menempuh pendidikan Strata 1 Program Studi Pendidikan Bahasa dan Sastra Indonesia, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Muhammadiyah Tangerang. Untuk menemukan interferensi morfologi dalam karangan narasi, peneliti menggunakan metode deskriptif kualitatif, dan dianalisis dengan metode analisis isi. Teknik pengumpulan data menggunakan teknik dokumentasi berupa hasil karangan narasi tujuh mahasiswa Thailand, dari data yang diperoleh peneliti menganalisis bentuk-bentuk interferensi dari bentuk afiksasi, reduplikasi, dan pemajemukan dalam bahasa Indonesia. Teknik analisis data dengan langkah-langkah: teknik analisis isi dimulai dengan menentukan masalah penelitian, kategorisasi, interpretasi, dan kesimpulan. Berdasarkan hasil penelitian terdapat interferensi pada karangan narasi mahasiswa Thailand semester IV PBSI FKIP Universitas Muhammadiyah Tangerang. Di dalam karangan yang mahasiswa buat, terlihat mahasiswa masih menggunakan bahasa Melayu dalam berkomunikasi secara lisan maupun tulisan. Temuan penelitian ini, juga menunjukkan bahwa banyaknya kata yang terinterferensi pada bentuk afiksasi kategori prefiks, sufiks, kombinasi afiks, konfiks, reduplikasi, dan komposisis sedangkan pada afiks kategori infiks tidak terdapat interferensi. Bentuk yang sering terinterferensi adalah pada bentuk afikasisi kategori prefiks, konfiks, dan komposisi dari ke enam karangan mahasiswa. Kata kunci: interferensi morfologi, karangan narasi, mahasiswa Thailand Abstract The objective of this research was to describe the forms of morphological interference of Thai Malay to Indonesian in the narrative of Thai students of the 4th semester who studied in Strata 1 Indonesian Language and Literature Education Study Program, Faculty of Teacher Training and Education, Muhammadiyah Tangerang University. To find morphological interference in narrative essay, the researcher uses qualitative descriptive method, and analyzed by content analysis method. Data collection techniques used documentation techniques in the form of a narrative of seven Thai students, from data obtained by researchers analyzing the forms of interference from the form of affixation, reduplication, and compounding in the Indonesian language. Data analysis techniques with steps: content analysis techniques begin by determining research problems, categorization, interpretation, and conclusions. Based on the result of the research, there is interference on student narration of Thailand semester IV PBSI FKIP, Muhammadiyah Tangerang University. In the essay that the students make, it is seen that students still use Malay language in communicating orally and in writing. The findings of this study also show that the number of interferenced words in the form of affixation of categories of prefixes, suffixes, affix combinations, confix, reduplication and compositions whereas in the affix of the infix category there is no interference. Frequently interfered forms are in the form of affiliation categories of prefixes, confixes, and compositions of the six student compositions. Keywords: morphological interference, narrative essay, Thai college students
Pengaruh Penggunaan Model Pembelajaran Examples Non-Examples terhadap Hasil Belajar Menulis Teks Berita pada Siswa Kelas VIII SMPN 14 Kota Tangerang Agus Sulaeman; Ariyana Ariyana
Silampari Bisa: Jurnal Penelitian Pendidikan Bahasa Indonesia, Daerah, dan Asing Vol 1 No 2 (2018): Silampari Bisa: Jurnal Penelitian Pendidikan Bahasa Indonesia, Daerah, dan Asing
Publisher : LP4MK STKIP PGRI Lubuklinggau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (386.006 KB) | DOI: 10.31540/silamparibisa.v1i2.201

Abstract

The objective of this research was to determine the effect of the use of examples non examples models in class VII students of Class VIII SMPN 14 Tangerang City the method used in this study was the quasi experimental method by pretest and posttest two groups. This type of experimental research method uses the Nonequivalent Control Group Design research design. Where the experimental class is treated and the control class is not treated. The Nonequivalent Control Group Design is almost the same as the pretest and postest control of the design group, only in this design the experimental and control groups are not randomly selected. Data collection techniques using tests. The data analysis technique starts from the normality test, homogeneous test, and continues the hypothesis test. There are differences in learning outcomes of writing news texts between students who were given examples non-examples learning models with students who were not given examples non-examples learning and evidenced by the results of hypothesis testing, namely the pretest in the control class and the Ho accepted H1 experiment were rejected, it can be concluded that tcount < ttable (0.41 <2.0021) then the pretest did not have a significant difference in learning outcomes, and the results of the posttest hypothesis on the control class and experimental class were H1 accepted Ho was rejected because thitung> t table = 3.03 > 2.0021, then it can be stated that the giving of posttest in the control class that did not get treatment and the experimental class to get treatment using the examples non-examples learning model showed a very significant difference in learning outcomes.
Hubungan Motivasi Belajar dengan Hasil Pembelajaran Bahasa Indonesia bagi Penutur Asing (BIPA) pada Mahasiswa Semester 7 Program Studi Pendidikan Bahasa dan Sastra Indonesia FKIP Universitas Muhammadiyah Tangerang Agus Sulaeman; Winda Dwihudhana
Silampari Bisa: Jurnal Penelitian Pendidikan Bahasa Indonesia, Daerah, dan Asing Vol 2 No 1 (2019): Silampari Bisa: Jurnal Penelitian Pendidikan Bahasa Indonesia, Daerah, dan Asing
Publisher : LP4MK STKIP PGRI Lubuklinggau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (380.279 KB) | DOI: 10.31540/silamparibisa.v2i1.327

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This study aims to determine the relationship between learning motivation towards the learning achievement of Indonesian language for non native speakers (BIPA) at 7th semester students in Indonesian Language and Literature Study Program. The research methods used was quantitative method with correlation design. The instruments of research were interviews, observation and questionnaire respondents' statements to 40 students at 7th semester. This was done in order to find out how the relationship between learning motivation and learning achievement by using correlational, determination and significance test. The purpose was to improve and evaluate the learning achievement. Due to the results of the calculation analysis by using Pearson correlation coefficient formula, there was a positive effect of correlation between learning motivation towards the learning achievement, which was equal of r = 0.50 that includes a fairly strong category (0.40–0.599). The results of testing the formula of t count is > t table that is 0.62 > 0.31, which means that H0 was rejected and H1 was accepted. It means, the learning motivation as variable X has a significant influence on the learning achievement as variable Y. So, BIPA teaching materials are appropriate to be designed.
Interferensi Bahasa Betawi di Kampung Gondrong Kota Tangerang Agus Sulaeman; Ahmad Suherman; Mutoharoh Mutoharoh
Silampari Bisa: Jurnal Penelitian Pendidikan Bahasa Indonesia, Daerah, dan Asing Vol 3 No 2 (2020): Silampari Bisa: Jurnal Penelitian Pendidikan Bahasa Indonesia, Daerah, dan Asing
Publisher : LP4MK STKIP PGRI Lubuklinggau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31540/silamparibisa.v3i2.974

Abstract

The purpose of this study was to describe the Betawi language interference in the conversations of the people of Gondrong Village, Cipondoh, Tangerang City. The research method used is descriptive qualitative. The data in this study were from the spoken language of the native speakers in Gondrong Village, Tangerang City. Determination of the research area is determined based on the location where the researcher lives. The informants of this study, namely: native speakers of the studied language, had no abnormalities in pronunciation, and had good memory. The instrument in this study was the researcher himself assisted by morphological interference tables and phonological structure tables. This study uses interview techniques, namely conversations are analyzed by paying attention to each word. Data recorded, listened to, and recorded. This is to complement the collected data. Data analysis used the match and divide method with various techniques adapted to the character of the data obtained and the research objectives. Next, words that show signs of morphological and phonological interference are highlighted and recorded, then the correctness of the words is checked using the Big Indonesian Dictionary. The results showed that the people of Gondrong Village conducted morphological interference in the Betawi language in their daily dialogues. The forms of interference contained in the dialogue are words and affixes (affixes). The form of affix that is inferenced is the form of prefix, suffix, and confix, while the interference in the infix form is not found.