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Analisa Kadar Asam Lemak Bebas Dalam Minyak Goreng Curah Secara Alkalimetri Rosa Mardiana; Azmalina Andriani; Fathur Ridha
Journal of Pharmaceutical and Health Research Vol 1 No 1 (2020): Februari 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.856 KB)

Bulk cooking oil is cooking oil produced from palm oil, which is filtered only once so that the color looks different from clearer branded cooking oil. The repeated use of oil experiences oil destruction or damage caused by oxidation and hydrolysis processes that break down oil molecules into acids. This process gets bigger with high heating and long time during food frying. The research method used in this study uses a systematic sampling technique of random sampling, and data processing using the alkalimetry method. The results of the analysis of free fatty acids in Alcalimetrid bulk cooking oil in 50 ml ethanolutanol obtained levels of 0.68%, 0.53%, 0.43%. While in 75 ml ethanol ethanol were 0.86%, 0.64%, 0.52%. In the principle of analysis of free fatty acid levels with a strong base pH of the solution at an equivalent point above 8-10, the indicator used phenolphthalein will occur pink at the endpoint of the titration. From the results of the analysis of free fatty acid levels obtained from the three bulk cooking oil agents showed that the oil quality was not good for use because it caused a high auto-oxidation process. The process of autooxidation is the absorption of oxygen in the air by oil. So it can be concluded that the higher the level of free fatty acids, the higher the absorption of oxygen so that it can affect the taste of the oil, for example, oil is rancid. And if consumed with a long time will cause the emergence of cholesterol, coronary heart disease, cough, and sore throat

Analisis Natrium Siklamat Dalam Minuman Tebu(Saccharum Officinarum, L) Secara Spektrofotometri Lidyawati Lidyawati; Rosa Mardiana; Dwi Putri Rejeki; Jauhari Jauhari
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Sodium Cyclamate is one type of sweetener that is permitted, although being allowed to use excess sodium cyclamate can lead to cancer formation. Long-term consumption of sodium cyclamate can lead to metabolism of sodium cyclamate into cyclohexilamine compounds. The purpose of this study was to determine how much sodium cyclamate is used, whether it exceeds the maximum limit of 500 mg / kg weight of the material that has been determined. The sample used was a sample of sugarcane juice sold in Darussalam, which was then examined at the Chemical Laboratory of UIN Ar-raniry and FKIP Kimia Unsyiah Banda Aceh. The analytical method used is quantitative analysis using the UV-vis spectrophotometry method to determine the sodium cyclamate level. The results showed that the 4 samples used were negative containing sodium cyclamate with the level of Sample I = -449.8 Sample 2 = -426.4 Sample 3 = -520.6 Sample 4 = -444.8.

Identifikasi Formalin Pada Ikan Segar di Pelabuhan Pendaratan Ikan Idi Rayeuk Kabupaten Aceh Timur Rosa Mardiana; Lidyawati Lidyawati; Muhammad Zulfikri
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Indonesia is the second largest country after China in terms of capture fisheries production. Capture fisheries production in Indonesia in 2016 reached 6.83 million tons with a value of Rp. 125.3 trillion. The abundant fishery potential causes the fish preservation process at the fishermen level to be constrained. The limited number of preservatives that are safe for food makes formaldehyde an alternative preservative. The use of formaldehyde in food can cause poisoning to the human body.In the formaldehyde test conducted by the Integrated Supervision Team of the Aceh Marine and Fisheries Service (DKP) in 2017 it was found that the practice of using formalin as a fish preservative was still used by some fishermen and fish traders in Indonesia. Aceh. This research was conducted to determine the sustainability of the practice of using formaldehyde by fishermen and traders by identifying the formalin content in tuna and mackerel in Idi Rayeuk Fish Landing Port, East Aceh Regency. The samples used in this study were 3 tuna and 3 mackerel fish taken randomly at the Idi Rayeuk Fish Landing Site, East Aceh. The results showed that all samples tested showed negative results or the fish did not contain formaldehyde. This shows that the public and fishermen's awareness of the dangers of formaldehyde is very good.

Formulasi Sediaan Sabun Padat Dari Ekstrak Kulit Pisang Awak (Musa Balbisiana) Secara Maserasi Rosa Mardiana; Yuniati Yuniati
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Indonesia is the largest producer of bananas, along with the high productivity of bananas, the amount of banana peel waste also increases. When harvesting bananas, banana peels, stems and leaves (about 80%) are only removed without further processing. This is what causes the potential for banana peel waste to be large enough so that it is necessary to overcome the banana peel so that it has good value. The content in banana peels include carbohydrates, protein, fat, calcium, iron, phosphorus, vitamins B, C and C. Banana peel also has a cellulose content of 14.4%, an abundant amount, especially from banana peels, can be used as an efficient product. The method used in this study used the maceration method where the banana peel extract (Musa balbisiana) was made in the form of solid soap. which is heated and then the application of oil which is directly reacted with an alkaline solution at a temperature of 50˚C, so that a soap base is obtained. The solid soap preparation tests carried out in this study were organoleptic tests, pH tests and foam stability tests. The results of the evaluation of the preparation showed that the soap preparation was solid, there was no change in shape and odor, and had a pH that was in accordance with the standards for skin.

Uji Efek Antifungi Ekstrak Daun Biduri (Calotropis Gigantea L.) Terhadap Pertumbuhan Jamur Trichophyton Mentagrophytes Safrida Safrida; Rosa Mardiana; Nurul Husna
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

The leaf of biduri (Calotropis gigantea L.) is one of the plants that can be used as antifungal. Biduri leaves are used as antifungals based on the chemicals contained in them such as tannins, flavonoid saponins and polyphenols. The fungus Trichophyton mentagrophytes can cause a skin disease characterized by the appearance of circular and scaly patches or small bubbles known as Tinea or ringworm. This fungus has a habitat (especially in tropical and wet climates) in soil, humans and animals. This study aims to determine the effectiveness of biduri leaf extract (Calotropis gigantea L.) in inhibiting the growth of the fungus Trichophyton mentagrophytes and to determine what is the optimal concentration of biduri leaf extract (Calotropis gigantea L.) to inhibit the growth of the fungus Trichophyton mentagrophytes. This research was carried out at the Microbiology Laboratory of the Tarbiyah Faculty of UIN Ar-Raniry and the Chemical Laboratory of the Chemical Science Faculty, Syiah Kuala University, Banda Aceh, from 26 April to 21 August 2018. Biduri leaves were extracted using the maceration method which were soaked for 5 days with 2 repetitions and evaporated with using a rotary evaporator to obtain extract as much as 30 ml blackish green and thick. Inhibition test against the fungus Trichophyton mentagrophtes was carried out using the disc diffusion method on Potato Dextrose Agar (PDA) media with concentrations of 20%, 35% and 50%. Ketoconazole antifungal was made in suspension form as a positive control and aquadest as a negative control. The results showed that the diameter of the inhibition zone obtained from biduri leaf extract at a concentration of 50% of 9.16 mm was included in the medium category, at a concentration of 35% of 8.66 mm was included in the medium category, 20% concentration of 8.16 mm was included. in the medium category, 11.83 mm of ketoconazole suspension was included in the strong category and 0 mm of aquadest which had no inhibitory power.

Formulasi Sediaan Lotion Dari Ekstrak Buah Alpukat (Persea Americana) dan Lidah Buaya (Aloe Vera) Untuk Kulit Kering Marlia Oktaviana; Dwi Putri Rejeki; Ria Ceriana; Rosa Mardiana; Sasmiati Farach Dita
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.896

Skin care is needed so that the skin does not become dry, rough, and dull. The way to deal with dry skin is to use a scrub or use a moisturizer such as lotion. One of the active substances contained in lotion preparations is antioxidant compounds. Avocado and aloe vera extracts have antioxidant activity. Avocado and aloe vera have moisturizing benefits. In this study, both types of extracts were formulated into lotion preparations. Avocado and aloe vera extracts were made by maceration method using 70% ethanol as solvent. The extract was formulated with 3 variations, namely the control formula (F0), the avocado extract formula with a concentration of 5% (FI), and aloe vera with a concentration of 10% (F II). The lotion was tested for physical properties including pH, homogeneity, stability, spreadability and irritation tests. The results showed that the lotion containing avocado and aloe vera extracts with storage for two weeks was stable. Does not change shape, smell, color, and does not irritate the skin

Formulasi Sediaan Lip Gloss Dari Esktrak Etanol Ubi Jalar Ungu (Ipomoea Batatas L) Novia Agustia; Rosa Mardiana
Journal of Pharmaceutical and Health Research Vol 2 No 3 (2021): Oktober 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Indonesia is a country rich in natural plants that can be used as dyes for cosmetics, one of which is purple sweet potato (Ipomoea batatas L.). This purple sweet potato (Ipomoea batatas L.) grows in the tropics and produces 1.9 million tons of productivity per year. Purple sweet potato (Ipomoea batatas L.) is a natural dye and is safer than synthetic dyes. According to (Dian, 2017), purple sweet potato (Ipomoea batatas L.) contains anthocyanin dyes which play a role in inhibiting the activity of the amulase enzyme and can function as antioxidants. Antioxidants have a function to moisturize the lips and remove dead skin cells, besides that antioxidants are also needed by the body to neutralize free radicals. Lip gloss is a type of lip color preparation that contains high oil so that it gives a moisturizing, shiny or gloss impression. This study used purple sweet potato (Ipomoea batatas L) extract as a natural dye. This study aims to formulate purple sweet potato extract in the form of lip gloss and to see how good the stability of lip gloss is. Purple sweet potato (Ipomoea batatas L) extract was prepared by maceration using 96% ethanol solvent to obtain a liquid extract and then concentrated using a vacuum rotary evaporator to obtain a thick extract. The lip gloss formulation consisted of cera alba, liquid paraffin, vaseline album, emulsifying wax, BHT (Butyl Hydroxy Toluene) nipagin, glycerin, oleum ricini and the addition of purple sweet potato extract coloring. Concentrations used in lip gloss are 0% (F0), 20% (F1), and 35% (F2). Evaluation of lip gloss preparations included organoleptic test, homogeneity, smearing power, pH test, preference and irritation test. The results of the evaluation of the preparations showed that the preparations were homogeneous, and met the requirements well. The results of the smear test showed that the concentrations of 0% (F0), 20% (F1), and 35% (F2) were attached. The results of the preference test showed that at a concentration of 35% (F2) the panelists preferred the most. So it can be concluded that the best preparation is found at a concentration of 35% (F2).

Formulasi Sediaan Gel Dari Ekstrak Etanol Herba Pegagan (Centella asiatica (L) Urb) Nurlatifah Nurlatifah; Lidyawati Lidyawati; Rosa Mardiana; Dwi Putri Rejeki; Mona Asiah
Journal of Pharmaceutical and Health Research Vol 3 No 1 (2022): February 2022
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Indonesia is a rich country in terms of flora and fauna diversity. Indonesia's wealth with various types of flora is a highlight for science, one of which is the gotu kola herb (Centella asiatica (L) Urb). The chemical compound asiaticoside is part of the triperoids contained in the gotu kola herb which has the potential as antibacterial, antifungal, antioxidant and anti-cellulite on the skin, suitable for topical preparations such as gels. This study aims to formulate a gel preparation from the ethanolic extract of the gotu kola herb (Centella asiatica (L) Urb) which meets the requirements of a good gel. The formulation of the gel preparation was carried out with concentrations of 20%, 25%, and 30%. Extracted by maceration method using 70% ethanol and in a vacuum rotary evaporator to obtain a thick extract. Evaluation of the gel preparation was carried out by organoleptic test, homogeneity test, pH test, dispersibility test, adhesion test and irritation test. The results of the evaluation carried out with the three concentrations met the requirements of the organoleptic test, homogeneity test, pH test, adhesion test and irritation test, but the ethanol extract gel of the gotu kola herb at concentrations of 20%, 25% and 30% did not meet the requirements for the good dispersion test

Pemanfaatan Tanaman Toga di Perkarangan Rumah untuk Meningkatkan Kekebalan Tubuh Ria Ceriana; Verawati Verawati; Rosa Mardiana; Lidyawati Lidyawati; Sasmiati Farach Dita; Dwi Putri Rejeki
Jurnal Abdidas Vol. 3 No. 3 (2022): June, Pages 355-611
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v3i3.570

Masyarakat khususnya ibu-ibu di Desa Beurangong Aceh Besar biasa menggunakan obat-obatan secara empiris. Hal tersebut dapat dilihat dari sebagian pekarangan rumah mereka ditanami dengan tanaman toga. Akan tetapi, masyarakat lain belum semuanya mengetahui jenis-jenis tanaman toga dan manfaat yang diberikan tanaman toga. Pengabdian masyarakat ini dilaksanakan oleh dosen-dosen Akademi Farmasi YPPM Mandiri sebagai wujud tri dharma perguruan tinggi. Kegiatan ini dihadiri oleh ibu-ibu di Desa Beurangong Kecamatan Lam Ateuk Kabupaten Aceh Besar. Metode pelaksanaan kegiatan ini adalah dengan memberikan penyuluhan secara oral dan melakukan diskusi berupa tanya jawab. Hasil kegiatan ini adalah sebagian masyarakat telah terbiasa menanam tanaman toga di pekarangan rumah. Ada sekitar18 jenis tanaman yang banyak di tanam di pekaranga rumah masyarakat.

PEMANFAATAN LIMBAH CANGKANG TIRAM (Crasosstrea gigas) SEBAGAI BAHAN ABRASIF DALAM PEMBUATAN LULUR UNTUK MENGANGKAT SEL KULIT MATI Rosa Mardiana; Roza Arisma; Lidyawati Lidyawati; Ria Ceriana
Serambi Journal of Agricultural Technology Vol 4, No 2 (2022): Desember
Publisher : Universitas Serambi Mekkah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32672/sjat.v4i2.5080

Radikal bebas merupakan ancaman bagi Kesehatan kulit, keberadaan radikal bebas dapat mempengaruhi produksi enzim yang dapat mempertahankan fungsi sel, antara lain menyebabkan kerusakan kolagen dan elastin sehingga kulit menjadi kendur dan kusam. Kulit kusam disebabkan karena adanya radikal bebas pada tubuh manusia. Membersihkan kulit sangatlah penting, baik untuk kebersihan maupun penampilan yang optimal. Pembersih kulit yang baik haruslah dapat menghilangkan minyak yang cukup untuk membuat kulit tampak bersih. Pembersih kulit yang baik seharusnya dapat menghilangkan minyak dan kotoran yang menempel dipermukaan kulit. Limbah cangkang tiram selama ini hanya dimanfaatkan sebagai bahan kerajinan dan hiasan, padahal cangkang tiram menyimpan kandungan zat seperti kalsium dalam jumlah tinggi yang dapat dijadikan sebagai bahan abrasive dalam pembuatan lulur/scrub. Kalsium tidak hanya penting bagi tulang, tapi juga diperlukan untuk menjaga Kesehatan kulit, mineral yang paling banyak ditemukan dilapisan epidermis untuk mempercepat regenerasi kulit. Penelitian ini bertujuan untuk membuat bahan abrasive dari cangkang tiram. Penelitian ini tentang Pemanfaatan Limbah Cangkang Tiram (Crassostrea gigas) sebagai bahan abrasive dalam pembuatan lulur untuk mengangkat sel kulit mati. Perbandingan dilakukan dengan 2 formulasi, yaitu: F1 dan F2. Parameter yang diamati berupa uji arganoleptik, uji pH, uji Homogentitas, uji iritasi serta uji kesukaan. Hasil penelitian menunjukkan bahwa kedua formula menunjukkan hasil yang baik, namun pada formula 2 (30%) menunjukkan bahwa hasil lebih banyak disukai oleh responden.

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