Article Per Year (5 Year)
p-Index From 2019 - 2024
0
P-Index
This Author published in this journals
All Journal Medical Journal of Indonesia
Mirna Robert D.R. van Beest Holle
Unknown Affiliation
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Antibody anti-H5N1 detection in poultry farmers and workers in poultry collection facilities in Indonesia, 2007 Setiawaty, Vivi; Sedyaningsih, Endang R.; Sudiro, Tjahyani M.; van Beest Holle, Mirna Robert D.R.; Pangesti, Krisna N.A.; Ibrahim, Fera
Medical Journal of Indonesia Vol 19, No 2 (2010): May
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.071 KB) | DOI: 10.13181/mji.v19i2.394

Abstract

Aim Between July 2005 and May 2008, Indonesia reported 133 H5N1 confirmed human cases with a case fatality proportion of 81%. Fifty-four percent of cases had a history of direct contact with poultry (chickens). Therefore, it is important to define the detection of antibody of H5N1 among people who have intensive contact with poultry have been exposed to H5N1 viruses.Methods We collected sera from healthy poultry-collecting-facility (PCF) workers in Jakarta and healthy poultry-farmers in Sukabumi which have close contact with poultry. Anti-H5N1 antibodies were tested with modified Haemagglutination Inhibition (HI) assay using A/Ck/Banten/05-1116/05(H5N1) antigen and with Neutralization (NT) assay using A/H5N1/Indo/05/IBCDC-RG virus.Results Among the 216 PCF worker sera and the 495 poultry-farmer sera that we collected, we found that all poultry-farmers were seronegative and one percent of poultry-collecting-facilities workers were seropositive by both HI and 1% by NT assays.Conclusions This study detected asymptomatic H5N1 virus infection among poultry workers in PCFs with intensive contact with various types of different poultry who had different titers of antibody, but no antibodies were detected among poultry farmers. (Med J Indones 2010; 19:124-9)Keywords: Avian infl uenza, farmers, poultry workers, seropositive
Co-Authors Endang R. Sedyaningsih FERA IBRAHIM Krisna N.A. Pangesti Tjahyani M. Sudiro Vivi Setiawaty