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Chemical constituents of ripe Momordica charantia by Gas Chromatography Mass Spectrometry (GCMS) Diah Miftahul Aini; Baiq Desy Ratnasari; Zul Hendry
INSOLOGI: Jurnal Sains dan Teknologi Vol. 1 No. 3 (2022): Juni 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.429 KB) | DOI: 10.55123/insologi.v1i3.359

Abstract

Momordica charantia, commonly called bitter melon, is a plant belonging to Cucurbitaceae family known for centuries for its nutritional properties. This plant have been used as folklore medicine for the management of hypertensions, cold, cough, and diabetes. The aim of the present study was to characterize the chemical constituents of ripe M. charantia from Lombok, Indonesia by Gas Chromatography Mass Spectrometry (GCMS). The method that used is maseration with ethanol as solvent. The ethanol extract of ripe M. charantia was characterized by gas chromatography-flame ionization detection and gas chromatography coupled with mass spectrometry analyses. The chemical constituent of ripe M. charantia that followed by GCMS were 2,4-Pentanediol (23,61 %), Eucalyptol (1,8-Cineole) (20,41 %), Trans (Beta)-Caryopyllene (10,07 %), 3-Decyn-2-ol  (9.54 %), Epiglobulol (7.82 %), Methyleugenol (7.15%), Beta-Selinene (5.80 %), Alpha-Selinene (5.43 %), and Alpha-Humulene (5.29 %). This is the first report on chemical screening of ethanol extract of ripe M. charantia and GC-MS analysis shows the presence of compounds which have medicinal properties.
Hubungan Antara Riwayat Sesak Nafas Dengan Resiko Terinfeksi COVID-19: The Correlation Between History of Dispnea and The Risk Of COVID-19 Infection Zul Hendry; Dedy Arisjulyanto; Romi Hidayat
Journal Nursing Research Publication Media (NURSEPEDIA) Vol. 1 No. 1 (2022): Journal Nursing Research Publication Media (NURSEPEDIA)
Publisher : Yayasan Lentera Mitra Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1028.307 KB) | DOI: 10.55887/nrpm.v1i1.4

Abstract

Latar Belakang: Coronavirus Disease 2019 (COVID-19) pertama kali ditemukan di Wuhan di Provinsi Hubei, China, penyebaran dan penularan Penyakit Coronavirus 2019 COVID-19 sangat cepat dan ditetapkan sebagai kasus pandemi global. Berdasarkan data WHO di dunia 8.993.659 kasus terkonfirmasi COVID-19, termasuk 469.587 kematian. Di Indonesia, kasus positif COVID-19 sebanyak 49.009 kasus positif dengan 2.573 kematian, dan di NTB sebanyak 1.119 kasus dengan 49 kematian. Riwayat sesak nafas menjadi salah satu faktor penyebab cepatnya penyebaran kasus ini. Tujuan: Tujuan dilakukannnya penelitian ini adalah untuk mengetahui hubungan riwayat sesak nafas dengan resiko terinfeksi COVID-19 di wilayah Nusa Tenggara Barat. Metode:  Metode: Penelitian ini menggunakan metode penelitian survei dengan wawancara tatap muka menggunakan kuesioner digital yang dilakukan di Provinsi Nusa Tenggara Barat dengan jumlah sampel 1.213 responden, dan hasil penelitian ini dianalisis menggunakan chi-square dan odds-ratio. Hasil: Hasil: Berdasarkan hasil analisis menggunakan gangguan pernafasan dengan risiko penularan virus Corona (COVID-19) diperoleh P-value 0,000 kurang dari 0,05 dengan Odds ratio 2,4. Kesimpulan: Terdapat hubungan antara riwayat sesak napas dengan risiko terinfeksi COVID-19, serta terdapat resiko 2,4 kali lebih cepat terpapar COVID-19 pada orang dengan riwayat sesak.
Malfungsi Seksualitas Wanita Usia Subur Yang Mengalami Diabetes Melitus Zul Hendry; Dedy Arisjulyanto; Nanik Ika Puspita
JURNAL KESEHATAN TROPIS INDONESIA Vol. 1 No. 1 (2023): Januari
Publisher : PT. LARPA JAYA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.012 KB) | DOI: 10.1234/jkti.v1i1.4

Abstract

Latar Belakang:Seks adalah fungsi utama manusia dan memiliki peran mendasar dalam kehidupan reproduksi. hasil study pendahuluan yang dilakukan pada di wilayah Wajageseng menggunakan kuesioner The Female Sexual Fuction Index (FSFI) didapatkan 17 dari 20 responden yang diwawancarai menunjukan mengalami gangguan seksual dan tidak ada hasrat untuk melakukan hubungan seksual, sedangkan 3 responden menyatakan tidak mengalami gangguan seksual dan masih melakukan hubungan sesksual dengan pasangannya.Metode: Desain penelitian ini adalah case control study. Populasi penelitian ini adalah seluruh wanita usia subur yang telah menikah di Wilayah Wajageseng, Kabupaten Lombok Tengah, dengan sampel penelitian sebanyak 96 responden yang dibagi menjadi 2 kelompok yaitu kelompok kasus dan kontrol yang dipilih dengan teknik sampling probability propostional size. Data yang dikumpulkan dianalisis menggunakan uji chi square dengan p<0,05.Hasil: Berdasarkan hasil penelitian dan pembahasan diatas makan dapat disimpulkan responden yang mengalami penyakit diabetes melitus dan mengalami malfungsi seksual sebanyak 36,46%, responden yang mengalami diabetes melitus dan tidak mengalami malfungsi seksual sebanyak 13,54%, sedangkan responden yang tidak mengalami diabetes melitus namun mengalami malfungsi seksual sebanyak 18,75 %, sedangkan responden yang tidak mengalami diabetes melitus dan tidak mengalami malfungsi seksual sebanyak 31,25% dan didapatkan nilai p value 0,000 <?=0,05 dan OR 5,6. Kesimpulan: Kesimpulan penelitian ini ada hubungan antara kejadian penyakit diabetes melitus dengan kejadian malfungsi seksual pada Wanita usia subur di wilayah Wajageseng, dan diketahui nilai OR 5,6 yang berarti Wanita usia subur dengan penyakit diabetes melitus memiliki resiko terjadinya malfungsi sesksual 5,6 kali lenih tinggi dibandingkan dengan Wanita usia subur yang tidak mengalami diabetes melitus..
Effect of giving Extract Ethanol from Bitter Gourd Fruit (Momordica Charantia L) on the Quality and Quantity of Mouse Spermatozoa (Mus Musculus) Zul Hendry; Radliyatul Fahmi
International Journal of Medicine and Health Vol. 2 No. 3 (2023): September : International Journal of Medicine and Health (IJMH)
Publisher : Amik Veteran Porwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijmh.v2i3.2195

Abstract

Men's participation in the Family Planning (KB) program is still very minimal due to the limited choice of contraceptive methods. Efforts need to be made to develop contraceptive methods, one of which is using natural ingredients. Bitter melon (Momordica charantia L) is known to have potential benefits as a male antifertility agent. This research used an experimental design with a sample size of 20 mice divided into 4 groups randomly. Treatment groups 1-3 were given different doses, namely 100, 80, 60 mg of bitter melon ethanol extract/100g BW/day, and the control group was given distilled water for 35 days. The mice were sacrificed the day after the last dose, then spermatozoa were collected from the epididymis and their number, motility, viability and morphology were examined. The results of this study showed a significant decrease in the number and motility of spermatozoa and was directly proportional to the size of the dose given. In terms of viability parameters, there was a significant decrease at all doses. Meanwhile, for spermatozoa morphology, only a dose of 100 mg had a significant impact. The conclusion from the results of this research is that giving bitter melon fruit extract has an effect on the number, motility, viability and morphology of spermatozoa. The most effective dose is 100 mg/100 gBB/day.
PENINGKATAN KUALITAS TIDUR PADA IBU RUMAH TANGGA DENGAN SENAM AEROBIK Elisa Oktaviana; Bahjatun Nadrati; Lalu Dedy Supriatna; Zulhendry Zulhendry
Jurnal LENTERA Vol. 4 No. 1 (2024): Jurnal LENTERA
Publisher : Stikes Yarsi Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/lentera.v4i1.324

Abstract

Sleep quality is a description that explains a person's ability to maintain sleep time and the absence of disturbances experienced during the sleep period. Sleep quality is an illustration of how a person can easily start sleeping and maintain sleep. The quality of a person's sleep can be seen from the aspect of the length of time they sleep, and the complaints they feel during sleep or after waking up. There are 431 housewives in Kekeri hamlet. This community service was carried out in May 2023 by first providing an explanation to housewives in East Kekeri hamlet of the benefits of aerobic exercise to improve sleep quality using the lecture method then continuing on the following day, namely implementing aerobic exercise every afternoon for housewives There were 18 people present. Participants were then given a questionnaire about sleep quality before and after doing aerobic exercise 3 times a week for 1 month with a total of 12 meetings. The results of community service activities that have been carried out in East Kekeri Hamlet show that there is a difference in the average quality of sleep before and after aerobic exercise where the quality of sleep has increased. Aerobic exercise has the effect of improving the quality of sleep in housewives, this is very useful so that people know how to treat insomnia independently in an easy way.