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All Journal Jurnal Rekayasa Proses Prosiding Seminar Nasional MIPA Jurnal Sains dan Teknologi Indonesian Journal of Biotechnology Jurnal Rekayasa Proses WIDYA LAKSANA Molekul: Jurnal Ilmiah Kimia INTERNATIONAL JOURNAL OF APPLIED CHEMISTRY RESEARCH
Ni Wayan Yuningrat
Universitas Pendidikan Ganesha
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Energy Immunology & microbiology Materials Science & Nanotechnology Social Sciences Other

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Journal : Indonesian Journal of Biotechnology

 1 
Study of creatinine transport through chitosan/pectin/poly(vinyl alcohol) blend membranes Ni Putu Sri Ayuni; Ni Wayan Yuningrat
Indonesian Journal of Biotechnology Vol 21, No 2 (2016)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1068.6 KB) | DOI: 10.22146/ijbiotech.25812

Abstract

Creatinine was final product of creatine metabolism inskeletal muscle. Increasing of creatinine showed decreasing of kidney function. Kidney fuction decreased could be treated by hemodialysis (HD). One of the natural polymer was cellulose which often used as hemodialysis membrane. Chitosan as natural membrane was used as membrane in this research because the structure was almost similar to cellulose. Chitosan was complexed by pectin and poly(vinil alcohol) (PVA) to fixed mechanical characteristic of membrane. The objective of this research were to synthesize, characterize, and know efficiency of creatinine transport using chitosan/pectin/PVA blend membranes. The functional groups of synthesized membrane were characterized by FTIR spectrophotometer. Efficiency of optimum creatinine transport was known by using membrane with chitosan and pectin ratio70:30 while PVA used 0.5%; 1.0% and 1.5%. The source and acceptor phase resulted were complexed by picric acid and analyzed by Ultraviolet-Visible (UV-Vis) Spectrophotometer. The result of membrane synthesized which was analyzed by FTIR Spectrophotometer shows that there is a band broadening on wave number 3448.72 cm-1. It is indicated that there are an overlapped stretching of hydrogen bond -OH on PVA and NH2 on chitosan. The optimum creatinine 70 ppm transported using membrane with 1.5% PVA addition is 59%. 
Co-Authors Andriani, Ketut Yesi DWI SURYANTO Gede Agus Beni Widana I Made Candra Wiguna I Nyoman Sujana I Putu Parwata I Wayan Mudianta Ketut Yesi Andriani Made Vivi Oviantari Ni Putu Sri Ayuni Ni Wayan Citra Ni Wayan Martiningsih Putu Frisca Dora Jastrissia Wiguna, I Made Candra