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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Abdi Insani
Frida M Yusuf
Universitas Negeri Gorontalo
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Physics

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IMPLEMENTASI KONSERVASI KELELAWAR BERKELANJUTAN DI DESA OLIBU PROVINSI GORONTALO Syafriyanto Dako; Nibras K Laya; Netty Ino Ischak; Frida M Yusuf; Frimawaty H Djafar; Suleman Daima
Jurnal Abdi Insani Vol 7 No 1 (2020): Jurnal Abdi Insani Universitas Mataram
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v7i1.293

Abstract

Implementasi konservasi kelelawar berdampak positif terhadap perkembangbiakan satwa ini dan sosial ekonomi bagi Masyrakat. Pengabdian Pada Masyarakat ini bertujuan memberikan pemahaman kepada Kelompok Masyarakat Pemanfaat Kelelawar tentang penerapan konservasi kelelawar berkelanjutan. Metode pelaksanaan melalui Penetapan wilayah konservasi in-situ, pembinaan Kelompok Pemanfaat Kelelawar melalui Model PRA, dan pengawasan wilayah konsevasi. Kegiatan ini dilaksanakan di Desa Olibu, Kabupaten Boalemo, Provinsi Gorontalo. Kelompok sasaran adalah Kelompok Pemanfaat Kelelawar yang berada di desa Olibuu, terdiri atas: Kelompok Accerodon, dan Alecto. Implementasi konservasi kelelawar didesa Olibu telah ditetapakan kawasan hutan manggorve sebagai kawasan konservasi In-situ bagi satwa kelelawar. Pengawasan wilayah konservasi dilakukan secara terpadu bersama masyarakat. Pembinaan kelompok memberi dampak terhadap peningkatan pengetahuan bagi Kelompok Pemanfaat Kelelawar. Tercapainya kesepakatan antara kelompok, Pemerintah Desa, Pemerintah Kecamatan, Perwakilan Masyarakat, dan Universitas Negeri Gorontalo tentang inplementasi konservasi kelelawar di Desa Olibu: Larangan penebangan hutan Mangrove 1), Larangan menggunakan senjata api atau sejenisnya untuk berburu kelelawar 2), Frekuensi menangkap kelelawar di lokasi in-situ di kurangi (2 kali dalam seminggu), dengan cara menggunakan Mist Net, dan dilakukan pada pukul 03.00 am - 05.00 am 3), sortasi kelelawar, dengan kriteria: kelelawar yang berukuran kecil, bunting dan menyusui anak, dilepaskan kehabitatnya 4)
Antipyretic Drug Candidates Through Reverse Docking Techniques Used In Science Learning Muhamad Iksan; Frida M Yusuf; Fitriani Fitriani B; Wa Ode Al Zarliani
Jurnal Penelitian Pendidikan IPA Vol 9 No 8 (2023): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i8.4863

Abstract

Red ginger (Zingiber officinale var. Rubrum) is a commonly used rhizome known for its fragrant and spicy taste. It contains gingerol and shogaol compounds that have antipyretic effects by inhibiting prostaglandin formation and stimulating the production of interleukin-10, an endogenous antipyretic. This study aimed to evaluate the potential of gingerol and shogaol compounds as antipyretic drug candidates through reverse docking techniques targeting interleukin-10 (IL-10). Ten natural compounds from red ginger were predicted for their potential as antipyretic drugs and docked with the IL-10 receptor protein using various computer programs. The molecular docking results showed that (6)-shogaol had four amino acid bond residues that were the same as the ibuprofen control compound, indicating its potential as an antipyretic drug candidate. Furthermore, (6)-shogaol had the same binding affinity as the control compound and was safe for oral consumption based on pharmacokinetic and toxicity tests using Lipinski's Rule, Toxtree, and admet-T. These findings suggest that (6)-shogaol is a promising antipyretic drug candidate compared to other compounds. In conclusion, this study identified the potential of (6)-shogaol as an antipyretic drug candidate through reverse docking techniques targeting interleukin-10. Red ginger could provide a natural alternative for antipyretic drugs, and further research is recommended to explore the role of gingerol and shogaol compounds in targeting other proteins
Co-Authors Fitriani Fitriani B Frimawaty H Djafar Laya, Nibras K. muhamad iksan Netty Ino Ischak Safriyanto Dako Suleman Daima Wa Ode Al Zarliani