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All Journal Health Science Journal of Indonesia Medical Journal of Indonesia The Indonesian Journal of Public Health The Indonesian Biomedical Journal Universa Medicina Journal of General Procedural Dermatology and Venereology Indonesia The Indonesian Journal of Community and Occupational Medicine Journal of General-Procedural Dermatology & Venereology Indonesia Occupational and Environmental Medicine Journal of Indonesia

Dewi Sumaryani Soemarko

Occupational Medicine Division, Departement Of Community Medicine, Faculty Of Medicine, Universitas Indonesia

Author-ID : 4375231

Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Past antihypertensive drugs, obesity, daily light working load and risk of hypertension: An Indonesian 2001 rural study Basuki, Bastaman; Soemarko, Dewi S.; Amri, Zarni; Ibrahim, Ermita I.
Medical Journal of Indonesia Vol 10, No 4 (2001): October-December
Publisher : Faculty of Medicine Universitas Indonesia

This study aims to identify some risk factors related to hypeertension in rural areas. The data for this study is a part af the result of the field study done by the second year medical students of the Faculty of Medicine, University of Indonesia, Jakarta, on June 27h , 2001, at Cijeruk subdistrict in Bogor regency. The subjects were seleccted randomly using neighborhood cluster which was diffirent from the previous study in 2000. Interviews and blood pressure were taken at the houses of the subjects from 1:00 PM to 4:00 PM. The results of this study showed that people aged 40 years or over had an increase risk to suffer hypertension compared to the 18-39 year old group, and the risk was most prominent among the 55-59 year group [adjusted odds ratio (OR)= 17.7; 95% confidence intervals (CI)=6.26-59.2). Compared to the subjects with normal body posture,those who were obese had more than two-fold increase in the risk to be hypertensive (adjusted OR= 0.87; 95% CI= 0.87-4.17; P= 0.109). In addition, those who discontinued antihypertensive drugs had almost 14-fold increase in the risk to be hypertensive relative to subjects who never take antihypertensive drugs (adjusted OR= 14.16; 95% CI= 7.14- 28.05). In general, the results of this study is similar with our last year study which used different subjects. This study concluded that special attention should be taken to the elderly aged 40 years and over, to some one who discontinued antihypertensive drugs; andwhom had light daily working load to prevent hypertension. (Med J Indones 2001; 10: 224-9)Keywords: hypertensive, risk factor, adjusted odds ratio, elderly.

Lymphocyte chromosome breakage in low benzene exposure among Indonesian workers Soemarko, Dewi S.; Mansyur, Muchtaruddin
Medical Journal of Indonesia Vol 23, No 4 (2014): November
Publisher : Faculty of Medicine Universitas Indonesia

Background: Benzene has been used in industry since long time and its level in environment should be controled. Although environmental benzene level has been controlled to less than 1 ppm, negative effect of benzene exposure is still observed, such as chromosome breakage. This study aimed to know the prevalence of lymphocyte chromosome breakage and the influencing factors among workers in low level benzene exposure.Methods: This was a cross sectional study in oil & gas industry T, conducted between September 2007 and April 2010. The study subjects consisted of 115 workers from production section and head office. Data on type of work, duration of benzene exposure, and antioxidant consumption were collected by interview as well as observation of working process. Lymphocyte chromosome breakage was examined by banding method. Analysis of relationship between chromosome breakage and risk factors was performed by chi-square and odd ratio, whereas the role of determinant risk factors was analyzed by multivariate forward stepwise.Results: Overall lymphocyte chromosome breakage was experieced by 72 out of 115 subjects (62.61%). The prevalence among workers at production section was 68.9%, while among administration workers was 40% (p > 0.05). Low antioxidant intake increases the risk of chromosome breakage (p = 0.035; ORadjusted = 2.90; 95%CI 1.08-7.78). Other influencing factors are: type of work (p = 0,10; ORcrude = 3.32; 95% CI 1.33-8.3) and chronic benzene exposure at workplace (p = 0.014; ORcrude = 2.61; 95% CI 1.2-5.67), while the work practice-behavior decreases the lymphocyte chromosome breakage (p = 0.007; ORadjusted = 0.30; 95% CI 0.15-0.76).Conclusion: The prevalence of lymphocyte chromosome breakage in the environment with low benzene exposure is quite high especially in production workers. Chronic benzene exposure in the workplace, type of work, and low antioxidant consumption is related to lymphocyte chromosome breakage. Thus, benzene in the workplace should be controlled to less than 1 ppm, and the habit of high antioxidant consumption is recommended.

Co-Authors Ade Mutiara Aditya Agung Prasetyo Ambar Roestam Ambar W Roestam Arriz Akbar Sukadi Bastaman Basuki Bernath Siagian Dewi Yunia Fitria Dewi Yunia Fitriani Ermita I. Ibrahim Faisal Yunus Fifinela Raissa Firly Ratsmita Fita Rahmasari Fuk, Liem Jen Githa Rahmayunita Githa Rahmayunita Herlinah Herlinah Herqutanto Herqutanto Herqutanto Herqutanto Herqutanto2 Imron Khazim Indah S. Widyahening Irwan Suhadi Iwan Sugiarta Iwan Susilo Joko Izzatul Abadiyah Kresna, Andreas Lim Jen Fuk Lusi Sandra Hutahaean Marsen Isbayu Putra Marsen Isbayuputra Monintja, Keyne Christa Muchtaruddin Mansyur Muhammad Ilyas Muhammad Ilyas Mulyana Mulyana Novi Silvia Hardiany Nuri Purwito Adi Nuri Purwito Adi Nuri Purwito Adi Raissa, Fifinela Ray Wagiu Basrowi Retno A. Werdhani SEPTELIA INAWATI WANANDI Slamet Ichsan Sri L. Menaldi Sri Linuwih Susetyo Wardhani, Sri Linuwih Susetyo Sudadi Hirawan Tenny Sutarto Vani Nur Pratami Wibowo, Suryo Yessi Kualasari Zarni Amri

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