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All Journal Pediatric Sciences Journal
Rusdian N. Ningsih
Department of Child Health, Faculty of Medicine, Brawijaya University, Saiful Anwar Hospital, Malang, Indonesia
Health Professions Public Health

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Fecal secretory immunoglobulin a, human ß defensin-2, and calprotectin levels in preterm neonates who consumes breast milk only, formula milk only, and combination Eko Sulistijono; Putri Primawardani; Rusdian N. Ningsih; Bernardinus P.A. Pradipta
Pediatric Sciences Journal Vol. 1 No. 2 (2020): (Available online 1 December 2020)
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (753.063 KB) | DOI: 10.51559/pedscij.v1i2.16

Abstract

Background: Secretory immunoglobulin A, human ß-defensin2 and calprotectin play an essential role in digestive system defense. This study aims to assess fecal SIgA, hBD-2, and calprotectin in preterm neonates (as inflammation marker) with different feeding patterns. Method: This study was cohort designed included 39 preterm neonates, which were categorized into breast milk only, formula milk only, and combination. Fecal SIgA, hBD-2, and calprotectin measured by ELISA. Results: Fecal SIga in the breast milk only group were significantly higher (p<0.005). Fecal HBD-2 and calprotectin in the formula milk only group were highest but not significantly different (p=0.463) with the combination group. Conclusion: Fecal SIgA levels that consumed breast milk only were significantly higher. Fecal HBD-2 and calprotectin levels that consumed formula milk only were highest but not significantly different from the combination group.
Co-Authors Bernardinus P.A. Pradipta Eko Sulistijono Putri Primawardani