Pediatric Sciences Journal
Vol. 1 No. 2 (2020): (Available online 1 December 2020)

Fecal secretory immunoglobulin a, human ß defensin-2, and calprotectin levels in preterm neonates who consumes breast milk only, formula milk only, and combination

Eko Sulistijono (Department of Child Health, Faculty of Medicine, Brawijaya University, Saiful Anwar Hospital, Malang, Indonesia)
Putri Primawardani (Department of Child Health, Faculty of Medicine, Brawijaya University, Saiful Anwar Hospital, Malang, Indonesia)
Rusdian N. Ningsih (Department of Child Health, Faculty of Medicine, Brawijaya University, Saiful Anwar Hospital, Malang, Indonesia)
Bernardinus P.A. Pradipta (Department of Child Health, Faculty of Medicine, Brawijaya University, Saiful Anwar Hospital, Malang, Indonesia)

Article Info

Publish Date
03 Feb 2022

Abstract

Background: Secretory immunoglobulin A, human ß-defensin2 and calprotectin play an essential role in digestive system defense. This study aims to assess fecal SIgA, hBD-2, and calprotectin in preterm neonates (as inflammation marker) with different feeding patterns. Method: This study was cohort designed included 39 preterm neonates, which were categorized into breast milk only, formula milk only, and combination. Fecal SIgA, hBD-2, and calprotectin measured by ELISA. Results: Fecal SIga in the breast milk only group were significantly higher (p<0.005). Fecal HBD-2 and calprotectin in the formula milk only group were highest but not significantly different (p=0.463) with the combination group. Conclusion: Fecal SIgA levels that consumed breast milk only were significantly higher. Fecal HBD-2 and calprotectin levels that consumed formula milk only were highest but not significantly different from the combination group.

Copyrights © 2022




Citation Download
RIS
EndNote, Reference Manager, ProCite
BibTex
Latex, Jabref
Full PDF
753.063 KB
Original Source
Download Original
Google Scholar
Check in Google Scholar
Journal Info
Pediatric Sciences Journal
Website

Abbrev

pedscij

Publisher

Universitas Brawijaya

Subject

Health Professions Public Health

Description

Pediatric Sciences Journal (PedSciJ) is published by the Medical Faculty of Brawijaya University, Indonesia, as an Open Access & Peer Reviewed Multidisciplinary Journal. The aims and scope of the Journal include pediatric, neonatal healthcare, and perinatology/ The Journal aims to bridge and ...