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All Journal Medica Hospitalia The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Prosiding Seminar Nasional Unimus
Hery Djagat Purnomo
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Humanities Dentistry Engineering Health Professions Medicine & Pharmacology Nursing Public Health

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Berbagai Faktor Risiko Retinopati Diabetik pada Penderita Diabetes Melitus Tipe 2 Nisa Khoirun Nafia; Trilaksana Nugroho; Arief Wildan; Hari Peni Julianti; Hery Djagat Purnomo
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 3 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.313 KB) | DOI: 10.36408/mhjcm.v8i3.596

Abstract

BACKGROUND: More than 75% of people with type 2 DM will anguish diabetic retinopathy 20 years after being diagnosed. However, the current changing of people’s lifestyle contributes to the tendency in type 2 DM that diagnosed at a younger age. This causes diabetic retinopathy can be occurred earlier and blindness will occur more quickly. It is important to prevent diabetic retinopathy by controlling some associated factors. OBJECTIVE: To investigate associated factors of diabetic retinopathy in people with type 2 DM. METHOD: Analytic observational study with cross-sectional design. Subjects were determined by purposive sampling. The subjects were interviewed using a questionnaire meanwhile, funduscopic examination is aimed to assess diabetic retinopathy and followed by deep interview. This study also used the subject’s medical record to complete the required data. The results were analyzed by using statistic software. RESULT: From 43 subjects, there wes no significant relation among age (p=0.965), gender (p=0.437), level of knowledge (p=0.640), accessibility (p=1.000), economic level (p=0.680), duration of DM (p=0.477), history of hypertension (p=0.708), and history of dyslipidemia (p=0.244) with diabetic retinopathy in people with type 2 DM. However, there was significant relation among controlling blood glucose (p=0.014) with diabetic retinopathy in people with type 2 DM. Uncontrolled blood glucose was 13 times more affected in diabetic retinopathy than controlled blood glucose (OR 13.417, 95% CI:1.474-122.117). CONCLUSION: There was a significant relation between controlling blood glucose and diabetic retinopathy in people with type 2 DM. Controlling blood glucose is the most dominant risk factor among the other factors in this study. Keywords: diabetic retinopathy; risk factor; type 2 diabetes mellitus
Seroprevalence Study of HbsAg positive in Entrant Candidates of Specialist Doctoral Program at Dr. Kariadi Hospital Semarang Hery Djagat Purnomo; Suyatmi Awizar
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 9, ISSUE 2, August 2008
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/92200842-44

Abstract

Background: Hepatitis B Virus (HBV) infection is one of main diseases that infects human kind and constitutes a serious health problem in community. As a consequence of their job, health personnel have gained higher risk to HBV infection. Medical personnel (doctors) are determined as one of the high-risk group of the HBV infection through blood transmission.The objective of this study was to determine the prevalence of HBsAg positive in doctors who were entrant candidates of medical specialist program at Dr. Kariadi hospital. Method: The study was conducted retrospectively by reviewing medical record of 1,145 doctors who were entrant candidates of medical specialist program at Dr. Kariadi hospital since April 2000 to October 2004. The HBsAg assay as a marker of HBV infection was analyzed by EIA (Enzyme Immuno Assay) Method. Results: Among the 1,145 doctors examined , the range of age was 29.34 ± 3.04 years, and more than 3-year work period as doctor was 64% (733/1,145), and less than 3-year work period as doctor was 36% (412/1,145). The prevalence of HBsAg positive in population was 3.9% (45/1,145). The seropositive of HBsAg in the group of doctors with more than 3-year work period was significantly higher than the group with less than 3-year work period (5.1% (38/73) vs. 1.6% (7/412) with p 0.05. Conclusion: The prevalence of HBsAg positive in doctors who were entrant candidates of specialist doctoral program at Dr. Kariadi hospital was 3.9%. The prevalence of infection was higher in the group of doctors with more than 3-year work period.   Keywords: prevalence, HBsAg, doctor
Gallstone and Diabetes Mellitus Hery Djagat Purnomo; Hirlan Hirlan
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 9, ISSUE 3, December 2008
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/93200886-90

Abstract

Diabetes Mellitus (DM) is a metabolic disease which has high prevalence among the population. The prevalence is increasing in accordance to life style changes in the society. Gallstone is frequently found in diabetic patients especially in women with type 2 DM. Nevertheless, studies on the prevalence of gallstone among diabetic patients population have shown inconsistent/contradictive results. Insulin resistance which is frequently found in type 2 DM patients is the underlying factor that correlates obesity, central adiposity, and low physical activity with gallstone disease. Two important physiological reasons in diabetic patients that may increase the risk of gallstone formation are: (1) Increased total cholesterol synthesis that causes bile becomes more easily transformed into cholesterol stone (lithogenic); (2) Diabetic patients have larger size and probably reduced motility of the gallbladder that cause increased formation of cholesterol crystals. However, recent study demonstrated that DM that merely exists without any contribution of other factors is not significant to increase the risk of gallstone formation. The gallstone management in diabetic patients is the same as the management in non-diabetic patients. Elective surgery with laparoscopic cholecystectomy is the treatment of choice for symptomatic cases. Drug treatment is indicated for patients with cholesterol stone, small stone (diameter 5 mm), and well-functioned cystic duct. Keywords: diabetes mellitus, gallstone, insulin resistance, cholesterol synthesis, motility, laparoscopic cholecystectomy
Chronic Diarrhea Caused by Amebic Colitis and Inflammatory Bowel Disease Hery Djagat Purnomo; Adjeg Tarius; Marcellus Simadibrata; Ari Fahrial Syam
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8, ISSUE 3, December 2007
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/83200795-99

Abstract

The diagnosis of intestinal amebiasis is easily established based on colonoscopy, i.e. there is a specific characteristic of ulcer/lesion “discrete flask-shape ulcer” with normal mucosa among the ulcers. However, most patients with amebic colitis have non-specific clinical manifestations and their colonoscopy findings are hardly distinguished from inflammatory bowel disease. In the present case, the patient had a chief complaint of chronic bleeding diarrhea and abdominal pain. The fecal analysis found trophozoites of Entamoeba histolytica. Serology test (sero-amebic) revealed negative result. The colonoscopy examination reveals hyperemic mucosa, edema, and multiple ulcers with various sizes covered with fragile and easily bleed debris, from the rectum to ascending colon, rigid colon, narrowing lumen and tumor/mass appearance on ascending colon. The differential diagnosis was severe amebic colitis and inflammatory bowel disease. Based on the colonoscopy biopsy, we found an active chronic colitis along with dysplasia. The patient received management and treatment of severe amebic colitis and inflammatory bowel disease. Keywords: amebic colitis, bleeding diarrhea, fecal analysis, colonoscopy, biopsy, inflammatory bowel disease
Seroprevalence Hepatitis C Reaktif pada Donor Palang Merah Indonesia Semarang, Jawa Tengah Galih Prakasa Adhyatma; Ajrina Luthfita; Arcita Hanjani; Andyta Nalaresi; Garda Widhi Nurraga; Anna Kartika Yuli Astuti; Hery Djagat Purnomo; Muchlis Achsan Udji Sofro
Prosiding Seminar Nasional Unimus Vol 3 (2020): Optimalisasi Hasil Penelitian dan Pengabdian Masyarakat Menuju Kemandirian di Tengah P
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Wilayah Asia Pasifik memiliki prevalensi infeksi Hepatitis tertinggi di dunia dengan 74% kematian akibat komplikasihepar terjadi di Asia. Pada tahun 2012, Hepatitis C diperkirakan memiliki prevalensi sebesar 0,39% berdasarkan datayang diambil dari Unit Transfusi Darah Pusat. WHO menetapkan target untuk mengurangi kejadian infeksi hepatitisbaru sebanyak 90% dan kematian akibat hepatitis sebanyak 65% pada tahun 2030. Penelitian dilakukan dengan metodedeskriptif observasional di Semarang pada September 2019 – Februari 2020. Data didapatkan dari catatan medispasien dari Januari 2009 – Desember 2019. Donor di Palang Merah Semarang yang memiliki skrining HCV-reaktifdan data rekam medis yang lengkap di inklusi ke dalam studi. Seroprevalensi Hepatitis C reaktif adalah 2267 donordari total pendonor 710.778 (0.3%). Prevalensi tertinggi ditemukan pada tahun 2009 (0.6%) dan yang terendah padatahun 2018 dan 2019 (0.2%). Pada tahun 2011 sampai dengan 2015 dan 2017 prevalensi adalah 0.3%. Pada tahun2010 dan 2016 prevalensi adalah 0.4%. Penelitian menunjukkan terdapatnya penurunan selama sepuluh tahun kohort.Usia rerata donor reaktif adalah 33.88 (SD 11.45) dengan jangkauan usia 16 – 67. 79.8% dari donor reaktif adalahlaki-laki dan 20.2% perempuan. Ditemukan 74.6% dari donor reaktif berdomisili di Semarang. Pekerja swastamerupakan pekerjaan yang paling banyak dimiliki oleh donor reaktif (55.5%). Infeksi HCV pada pendonor darahmerupakan masalah kesehatan masyarakat. Ditemukan bahwa terjadi penurunan pada prevalensi selama 10 tahunnamun belum mencapai target yang ditetapkan oleh WHO. Usaha penanganan dan pengendalian infeksi harusdilakukan dengan lebih giat untuk dapat mengurangi kejadian infeksi hepatitis virus baru. Kata Kunci: Seroprevalensi Hepatitis C, Hepatitis C, Palang Merah Indonesia Semarang, Hepatitis Virus, InfeksiMenular Lewat Transfusi Darah
Co-Authors Adjeg Tarius Ajrina Luthfita Andyta Nalaresi Anna Kartika Yuli Astuti Arcita Hanjani Ari Fahrial Syam Arief Wildan Galih Prakasa Adhyatma Garda Widhi Nurraga Hari Peni Julianti Hirlan Hirlan Marcellus Simadibrata Muchlis Achsan Udji Sofro Nisa Khoirun Nafia Suyatmi Awizar Trilaksana Nugroho