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All Journal Damianus Journal of Medicine Universa Medicina JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) Majalah Kedokteran Neurosains Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Cermin Dunia Kedokteran Neurona
Yvonne Suzy Handajani
Departemen Ilmu Kesehatan Masyarakat Dan Gizi, Fakultas Kedokteran Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Frailty decreases physical health domain of quality of life in nursing home elderly Handajani, Yvonne Suzy; Widjaja, Nelly Tina; Turana, Yuda
Universa Medicina Vol 34, No 3 (2015)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2015.v34.213-219

Abstract

BACKGROUND Approximately 10-27% of the population aged >65 years suffers from frailty. The percentage increases with age so that the prevalence of frailty in the population aged >85 years reaches 45%. The objective of this study was to determine the relationship between   frailty and quality of life (QOL) in nursing home elderly. METHODS This was a cross-sectional study of 138 subjects aged >60 years who were recruited from 4 nursing homes in West Jakarta. Participants with frailty status were evaluated by the Survey of Health, Ageing and Retirement in Europe (SHARE) instrument and QOL was evaluated by the WHOQOL-BREF questionnaire. One-way ANOVA and chi-square tests were used to find relations between the frailty syndrome and QOL. RESULTSThe percentages of respondents with pre-frail, frail, and non-frail status were 30.4%, 52.2%, and 17.4%, respectively. A decline in QOL scores of pre-frail and frail respondents was found for almost all QOL domains (physical, psychological and environment domains), except social relationships. The subdomains most influenced were “energy and fatigue” in the physical health domain, “thinking, learning, memory and concentration” in psychological health, and “opportunities for acquiring new information and skills” in the environment domain.CONCLUSIONS More than half of the nursing home elderly were frail and one-third were pre-frail. The main factor of frailty was weakness. The frailty syndrome in the elderly has a negative impact on QOL, especially in the physical health, psychological and environment domains in nursing home elderly.
DEFISIT NERVUS OLFAKTORIUS SEBAGAI FAKTOR RISIKO GANGGUAN MEMORI PADA LANSIA Vincentius Henry Sundah,* Yuda Turana,*Yvonne Suzy Handajani*
NEURONA Vol. 33 No. 3 Juni 2016
Publisher : Neurona Majalah Kedokteran Neuro Sains

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INTRODUCTION OLFACTORY DEFICIT BECOMES THE EARLY CLINICAL SIGN OF COGNITIVE FUNCTION IMPAIRMENT AMONG THE ELDERLY PEOPLE THIS RESEARCH FOCUSES ON SPECIFIC COGNITIVE FUNCTION IMPAIRMENT OF THE FRONTAL LOBE WHICH IS A REGION OF BRAIN THAT RESPONSIBLE WITH MANY FUNCTIONS INCLUDING OLFACTORY FUNCTION ATTENTION EXECUTIVE AND MEMORY COGNITIVE FUNCTION
EFEK PENURUNAN KEKUATAN GENGGAMAN TANGAN TERHADAP FUNGSI KOGNITIF DAN KESEIMBANGAN PADA LANJUT USIA Yvonne Suzy Handajani,1 Yuda Turana, 1,2 Nelly Tina Widjaja1
NEURONA Vol 34 No. 1 Desember 2016
Publisher : Neurona Majalah Kedokteran Neuro Sains

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Abstract

INTRODUCTION THE ABILITY TO GRIP IS ONE OF THE MOST IMPORTANT FUNCTIONS OF THE HAND HAND GRIP STRENGTH CAN BE USED TO REFLECT OVERALL MUSCULAR STRENGTH PREVIOUS STUDY SHOWED THAT MUSCULAR STRENGTH IS ASSOCIATED WITH COGNITIVE FUNCTION AND BALANCE DISTURBANCE IN ELDERLY PEOPLE
PENGARUH AKTIVITAS PENGASUHAN CUCU TERHADAP FUNGSI KOGNITIF PADA PEREMPUAN LANSIA Frederica Jovianti,* Linda Suryakusuma,* Yuda Turana,* Yvonne Suzy Handajani*
NEURONA Vol. 35 No. 3 Juni 2018
Publisher : Neurona Majalah Kedokteran Neuro Sains

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Abstract

INTRODUCTION COGNITIVE IMPAIRMENT IS A NEURODEGENERATIVE PROCESS WHICH OFTEN EXPERIENCED BY THE ELDERLY ONE OF THE FACTORS ASSOCIATED WITH COGNITIVE FUNCTION IS GRANDPARENTING WHICH IS COMMON AND HAS BECOME A SOCIAL NORM IN INDONESIA
FAKTOR RISIKO KOMORBID HIV DAN TUBERKULOSIS DI RUMAH SAKIT UMUM DAERAH MERAUKE Maria Anggi Sylvani; Yvonne Suzy Handajani; Lusia Gani
Majalah Kedokteran Indonesia Vol 69 No 6 (2019): Journal of the Indonesian Medical Association Majalah Kedokteran Indonesia Volum
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/jinma.v69i6.192

Abstract

Latar Belakang: Tuberkulosis merupakan salah satu penyakit yang memiliki hubungan erat dengan HIV. Infeksi HIV-TB berinteraksi secara langsung (bidireksional) dan sinergis. Faktor risiko seperti sosiodemografi, pola hidup, kadar CD4, kadar Hb dan konsumsi IPT dapat mempengaruhi terjadinya koinfeksi HIV-TB.Tujuan: Memperoleh gambaran prevalensi penyakit TB pada pasien HIV dan faktor-faktor determinannya di Rumah Sakit Umum Daerah Kabupaten Merauke, Papua.Metode: Penelitian ini dilakukan pada pasien HIV yang datang ke Pokja Rumah Sakit Umum Daerah Merauke (n=107). Desain penelitian adalah cross sectional dengan instrumen penelitian berupa wawancara dan rekam medis. Analisis univariat, bivariat , dan multivariat dilakukan menggunakan program pengolahan data SPSS versi 22 dengan uji statistic Chi Square pada tingkat kepercayaan 95%.Hasil: Hasil analisis bivariat pada penelitian ini menunjukkan kelompok pekerjaan (p=0,028), kelompok pendidikan (p=0,034), etnik/ras (p=0,042), lokasi tempat tinggal (p=0,033), kebiasaan merokok (p=0,012), aktivitas fisik (p=0,039), kadar CD4 (p=0,000), kadar Hb (p=0,000), Isoniazid Preventive Therapy (IPT) (p=0,016) berhubungan dengan koinfeksi HIV-TB.Kesimpulan: Faktor risiko berupa pekerjaan, pendidikan, etnik/ras, lokasi tempat tinggal, kebiasaan merokok, aktivitas fisik, kadar CD4, kadar Hb dan konsumsi IPT berpengaruh terhadap angka kejadian koinfeksi TB pada pasien HIV.
PENGARUH PENYAKIT KRONIS DAN GAYA HIDUP TERHADAP KINERJA VERBAL FLUENCY KATEGORIK PADA LANSIA Jessica Alysia,* Yvonne Suzy Handajani,* Nelly Tina Widjaja,* Yuda Turana*
NEURONA Vol. 37 No. 1 Desember 2019
Publisher : Neurona Majalah Kedokteran Neuro Sains

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Abstract

INTRODUCTION IN RECENT STUDIES CHRONIC ILLNESS AND SEDENTARY LIFESTYLE WERE FOUND TO BEA RISK FACTORS FOR COGNITIVE IMPAIRMENT VERBAL FLUENCY VF IS ONE OF THE MOST USED INSTRUMENTS
Life satisfaction is the most significant determinant of quality of life in the elderly Vinsalia, Thania; Handajani, Yvonne Suzy
Universa Medicina Vol. 40 No. 1 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.14-22

Abstract

BackgroundQuality of life tends to decrease as age increases. This study aimed to determine the most significant risk factors (family support, spirituality, and life satisfaction) for the elderly’s quality of life. MethodsThis was a cross-sectional study of 101 subjects aged ³60 years in West Jakarta. The variables were assessed using the World Health Organization Quality of Life–BREF (WHOQOL–BREF), Family Support, Daily Spiritual Experience Scale (DSES), and the Satisfaction with Life Scale (SWLS) instruments. Multivariate logistic regression was used to analyze the association between quality of life and its determinant factors.ResultsBased on sociodemographic characteristics, the respondents were mostly women (66.3%), had more than nine years of education (79.2%), and were married (56.4%). The analysis showed that life satisfaction was significantly associated with overall quality of life (OR=9.71; 95% CI:2.04–46.26; p=0.004) and general health (OR=7.52; 95% CI:1.70–33.25; p=0.008). Life satisfaction was also a risk factor for the environmental domain (OR=36.02; 95% CI:5.07–255.82; p<0.001). Furthermore, spirituality was found to be a risk factor for the physical health domain (OR=4.18; 95% CI:1.51–11.59; p=0.006), psychological domain (OR=6.67; 95% CI:2.4–17.86; p<0.001), and environmental domain (OR=11.46; 95% CI:3.10–42.37; p<0.001).ConclusionLife satisfaction plays a significant role in increasing the environmental domain of quality of life, the overall quality of life, and general health among the elderly. Awareness of these factors can assist providers in identifying people at risk and guide new intervention programs to improve care for these invaluable elderly of our communities.
STUDI KOHOR ATMA JAYA ACTIVE AGING RESEARCH: GANGGUAN KOGNITIF LANJUT USIA Suswanti, Ika; Budiharsana, Meiwita Paulina; Turana, Yuda; Handajani, Yvonne Suzy
Jurnal Publikasi Kesehatan Masyarakat Indonesia Vol 7, No 1 (2020): Jurnal Publikasi Kesehatan Masyarakat Indonesia
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpkmi.v7i1.8789

Abstract

ABSTRAK Gangguan kognitif merupakan bagian dari proses neurodegeneratif, saat ini belum ada  perawatan atau pengobatan untuk mencegah progresifitas. Tujuan penelitian ini adalah untuk mengetahui faktor risiko gangguan kognitif dalam studi prospektif. Penelitian dengan desain studi kohort prospektif pada 110 subjek dengan pengambilan sampel  dilakukan secara purposive sampling berdasarkan kriteria memiliki kognitif normal, pendidikan lebih dari 9 tahun dan berusia di atas 60 tahun yang berasal dari wilayah binaan Atma Jaya Active Aging Research yaitu Penjaringan, Cideng dan Cengkareng pada tahun 2014-2015 sebagai baseline studi. Fungsi kognitif diperiksa ulang setelah follow-up 2,5 tahun. Subjek diidentifikasi gangguan kognitif jika memiliki skor Mini Mental State Examination kurang dari 24. Penelitian kami menemukan bahwa 16,4% subjek mengalami gangguan kognitif dengan rerata usia  68,6 ± 6,3 tahun, dan 63 perempuan (57,3%). Skor Instrumental Activity Daily Living yang lebih rendah di awal studi memprediksi penurunan kognitif setelah 2,5 tahun follow up secara independen (13,9 ± 2,6 vs 15,3 ± 1,4; p-value= 0,001). Analisis multivariat menggunakan regresi logistik menunjukkan bahwa skor Instrumental Activity Daily Living yang lebih rendah memprediksi 1,47 kali untuk mengalami gangguan kognitif pada lanjut usia dengan pendidikan diatas 9 tahun setelah 2,5 tahun follow up. Nilai Instrumental Activity Daily Living yang lebih rendah ditemukan sebagai prediktor gangguan kognitif pada lansia setelah 2,5 tahun follow up. Kata-kata kunci: Neurodegeneratif, penilaian, fungsional, klinis, kohor  ABSTRACT Cognitive impairment is a part of neurodegenerative process, currently there was no treatment or medication to prevent the progressivity. The aims of the study was to investigate the risk factors of cognitive impairment in prospective study. The study was a prospective cohort study design on 110 subjects with sampling conducted by purposive sampling based on the criteria of having normal cognitive, education more than 9 years and aged over 60 years. The study based from the Atma Jaya Active Aging Research in Penjaringan, Cideng dan Cengkareng in 2014-2015 as the study baseline. The cognitive function was re-examined after a follow up 2.5-year. Subjects identified cognitive impairment if had Mini Mental State Examination score less than 24. Our study found that 16.4% subjects was cognitive impairment with mean of age 68.6±6.3 years, and 63 (57.3%) female. Lower Instrumental Activity of Daily Living score at baseline predicted cognitive impairment at the present (13.9±2.6vs15.3±1.4; p-value= 0.001). Multivariat analyses using regression logistic showed that lower Instrumental Activity Daily Living score predicting 1.47 more likely to progress cognitive impairment in elderly after follow up 2.5 years. Lower of Instrumental Activity Daily Living score found as a risk factor of worse cognitive funtion in elderly after 2.5-year prospective study.   Keywords: Neurodegenerative, functional, assessment, clinical, follow up  
Hubungan Pengetahuan dan Sikap tentang Malaria dengan Perilaku Pencegahan pada Kehamilan pada Ibu Hamil di Desa Muara Siberut dan Desa Maillepet, Mentawai, Indonesia Christy, Kezia; Tanumihardja, Tommy Nugroho; Handayani, Yvonne Suzy
Cermin Dunia Kedokteran Vol 46, No 5 (2019): Pediatri
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (532.379 KB) | DOI: 10.55175/cdk.v46i5.477

Abstract

Pendahuluan: Mentawai merupakan daerah dengan angka malaria terbesar di Sumatera Barat, namun masih sedikit penelitian mengenai pengetahuan, sikap dan perilaku pencegahan malaria terutama pada ibu hamil sebagai kelompok masyarakat berisiko tinggi. Metode: Penelitian analitik dengan desain penelitian cross sectional pada ibu hamil di Desa Muara Siberut dan Desa Maillepet, Mentawai, Sumatera Barat. Pengambilan data dengan wawancara responden dari rumah ke rumah menggunakan kuesioner. Data dianalisis dengan uji Chi square dan Fisher dengan Interval Kepercayaan 95% dan nilai kemaknaan p<0,05 menggunakan program SPSS 15.0 for Windows. Hasil: Dari 36 responden, 22 responden (61,1%) memiliki pengetahuan baik, 24 responden (66,7%) memiliki sikap positif, 27 responden (75%) tidak memiliki perilaku pencegahan. Tidak terdapat hubungan bermakna antara pengetahuan dengan perilaku (p=0,062) dan sikap dengan perilaku (p=0,706). Terdapat hubungan bermakna antara usia (p=0,020), jarak fasilitas kesehatan (p=0,020) dan peran tokoh panutan (p=0,001) terhadap perilaku pencegahan malaria terutama pada ibu hamil. Simpulan: Tidak terdapat hubungan bermakna antara pengetahuan dengan perilaku dan sikap dengan perilaku mengenai pencegahan malaria terutama pada ibu hamil. Terdapat hubungan bermakna antara usia, jarak fasilitas kesehatan dan peran tokoh panutan terhadap perilaku pencegahan malaria terutama pada ibu hamil. Perlu penelitian lebih lanjut mengenai metode efektif penyampaian informasi untuk masyarakat Mentawai serta pengaruh faktor budaya pada perilaku pencegahan malaria terutama pada ibu hamil.Introduction: Mentawai is a region with the most frequent cases of malaria in West Sumatera. There is still little research on knowledge, attitude and practice, especially about malaria in pregnancy as a high-risk group. Methods: An analytic study with a cross-sectional approach on pregnant women in Muara Siberut and Maillepet Village. Data were collected by house to house interview on respondents using questionnaires. Data were analyzed with chi square and Fisher method with 95% Confidence Interval and significance value of p<0,05. Results: Total respondents are 36 pregnant women, 22 (61,1%) have a good knowledge, 24 (66,7%) have a positive attitude, 27 respondents (75%) don’t have a preventive health practice. There were no significant relationship between knowledge and practice (p=0,062) on malaria prevention during pregnancy, no significant relationships between attitude and practiceon malaria prevention during pregnancy (p=0,706). There were significant relationships between age (p=0,020), distance of health clinic (p=0,020), and role of community leaders (p=0,001) towards practice on malaria prevention during pregnancy. Conclusion: No significant relationships between knowledge and practice on malaria prevention during pregnancy, also no significant relationship between attitude and practice on malaria in pregnancy. 
HIPERKOLESTEROLEMIA DAN APOE GENOTIP 44 SEBAGAI FAKTOR RISIKO GANGGUAN BAHASA PADA LANJUT USIA Stephanus Anggara,*Yoviana Adi Putra,* Josephine Retno Widayanti,* Yuda Turana,** Yvonne Suzy Handaj
NEURONA Vol 33 No 1 Desember 2015
Publisher : Neurona Majalah Kedokteran Neuro Sains

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Abstract

INTRODUCTION LANGUAGE IMPAIRMENT IS OFTEN THE EARLIEST SIGN OF COGNITIVE DECLINE IN THE ELDERLY
Co-Authors Benedicta Ann Clarabelle Thiantoro Budiharsana, Meiwita Paulina Christy, Kezia Kezia Christy Linda Suryakusuma Lusia Gani Maria Anggi Sylvani Melyana Tanuwijaya Nelly Tina Widjaja Pricilya H. Wangi sandy Ayu Monica Silalahi Suswanti, Ika Tanumihardja, Tommy Vinsalia, Thania Yuda Turana Yuda Turana