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Aktivitas Tabir Surya Formula Bedak Dingin Jawa Kusumanti, Diah Puti; Sayuti, Nutrisia Aquariushinta; AS, Indarto
Indonesian Journal of Pharmaceutical Science and Technology Supp 1, No 1 (2017)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Sinar matahari mengandung sinar ultraviolet yang mengakibatkan efek negatif pada kulit sehingga sediaan tabir surya dibutuhkan untuk melindungi kulit. Bedak dingin Jawa merupakan salah satu sediaan tabir surya yang telah digunakan secara empiris untuk melindungi kulit dari paparan sinar matahari. Formula bedak dingin Jawa tediri dari tepung beras (Oryza sativa L.), pati bengkoang (Pachyrhizu serorus (L.) Urb), kulit kayu manis jangan (Cinnamomum burmanii (nees) BI), pulasari (Alyxia reinwardtii BI), temugiring (Curcuma heyneana) dan biji pinang (Areca catechu L.). Penelitian ini bertujuan untuk mengetahui aktivitas tabir surya kombinasi tepung beras dan ekstrak sonikasi simplisia lain dalam formula bedak dingin jawa melalui pengujian nilai Sun Protection Factor (SPF), nilai persen transmisi eritema (%Te) dan pigmentasi (%Tp). Simplisia penyusun bedak dingin dibuat ekstrak dengan metode sonikasi dan dikombinasikan dengan tepung beras di dalam larutan dengan perbandingan 1:1 kemudian dilakukan pengujian aktivitas tabir surya dengan menggunakan spektrofotometri UV-Vis. Hasil penelitian ini adalah aktivitas tabir surya formula bedak dingin memiliki nilai SPF 15,6 dinyatakan dalam kategori proteksi maximal, nilai persen transmisi eritema 1,2 dinyatakan dalam kategori proteksi ultra, dan nilai persen transmisi pigmentasi 9,3 dalam kategori sunblock. Suatu sediaan tabir surya dinyatakan efektif dalam melindungi kulit bila memiliki nilai SPF yang tinggi, sedangkan nilai %Te dan %Tp efektif melindungi kulit bila nilainya rendah. Melalui penelitian ini dapat disimpulkan bahwa formula bedak dingin jawa efektif dalam melindungi kulit dari paparan sinar matahari. Kata Kunci : Aktivitas Tabir Surya, Bedak Dingin Jawa, SPF, Transmisi Eritema, PigmentasiÂ

Formulasi Hand & Body Lotion Antioksidan Ekstrak Lulur Tradisional Nutrisia Aquariushinta Sayuti; Indarto AS; Suhendriyo Suhendriyo
Interest : Jurnal Ilmu Kesehatan Vol 5 No 2 (2016): INTEREST : JURNAL ILMU KESEHATAN
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/interest.v5i2.51

Abstract: Scrub, Lotion, Antioxidants. Turmeric (Curcuma domestica L), Temu giring (Curcuma heyneana), cinnamon bark (Cinnamomum Bumani (nees) BI), Kemuning Leaf (Murraya paniculata (L) Jack) and sandalwood (Santalum album) was often combined in the manufacture of scrubs. This research aims to make Hand & Body lotion formula (H & B Lotion) antioxidant containing traditional herbal extract from the botanicals fifth practical that efficacious, stable, safe and preferred by consumers. This research was true experimental research. The antioxidant activity test was used the immersion method against free radical diphenyl -2- 1.1 picrylhydrazyls, the protection ability test using invitro test while irritation test and hedonic tests conducted on volunteers. Emulsions that tested were containing a traditional herbal extract with a concentration of 0.5%, 1.0%, and 1.5%. This study concluded that the H & B Lotion was stable with emulsifier concentrations of 4.5% Tween 80, the difference in concentration of the extract didn’t affect the protection ability and the safety of the product but it affect significantly on the efficacy of antioxidants and aroma sensory parameters on hedonic test’s results, Optimal antioxidant activity in traditional herbal extract concentration of 1.5%. The best products based assessment hedonic test was H & B lotion with extract content of 1.0%

Aktivitas Tabir Surya Formula Bedak Dingin Jawa Diah Puti Kusumanti; Nutrisia Aquariushinta Sayuti; Indarto AS
Indonesian Journal of Pharmaceutical Science and Technology Supp 1, No 1 (2017)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Sinar matahari mengandung sinar ultraviolet yang mengakibatkan efek negatif pada kulit sehingga sediaan tabir surya dibutuhkan untuk melindungi kulit. Bedak dingin Jawa merupakan salah satu sediaan tabir surya yang telah digunakan secara empiris untuk melindungi kulit dari paparan sinar matahari. Formula bedak dingin Jawa tediri dari tepung beras (Oryza sativa L.), pati bengkoang (Pachyrhizu serorus (L.) Urb), kulit kayu manis jangan (Cinnamomum burmanii (nees) BI), pulasari (Alyxia reinwardtii BI), temugiring (Curcuma heyneana) dan biji pinang (Areca catechu L.). Penelitian ini bertujuan untuk mengetahui aktivitas tabir surya kombinasi tepung beras dan ekstrak sonikasi simplisia lain dalam formula bedak dingin jawa melalui pengujian nilai Sun Protection Factor (SPF), nilai persen transmisi eritema (%Te) dan pigmentasi (%Tp). Simplisia penyusun bedak dingin dibuat ekstrak dengan metode sonikasi dan dikombinasikan dengan tepung beras di dalam larutan dengan perbandingan 1:1 kemudian dilakukan pengujian aktivitas tabir surya dengan menggunakan spektrofotometri UV-Vis. Hasil penelitian ini adalah aktivitas tabir surya formula bedak dingin memiliki nilai SPF 15,6 dinyatakan dalam kategori proteksi maximal, nilai persen transmisi eritema 1,2 dinyatakan dalam kategori proteksi ultra, dan nilai persen transmisi pigmentasi 9,3 dalam kategori sunblock. Suatu sediaan tabir surya dinyatakan efektif dalam melindungi kulit bila memiliki nilai SPF yang tinggi, sedangkan nilai %Te dan %Tp efektif melindungi kulit bila nilainya rendah. Melalui penelitian ini dapat disimpulkan bahwa formula bedak dingin jawa efektif dalam melindungi kulit dari paparan sinar matahari. Kata Kunci : Aktivitas Tabir Surya, Bedak Dingin Jawa, SPF, Transmisi Eritema, Pigmentasi

Uji Aktivitas Antiaging Invitro Lavender Body Butter Nutrisia Aquariushinta Sayuti
Jurnal Kebidanan dan Kesehatan Tradisional Vol 2 No 1 (2017): Jurnal Kebidanan dan Kesehatan Tradisional
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkkt.v2i1.27

Abstract : Lavender, Body Butter, Antiaging. Antiaging product must contain antioxidant and sunscreens compound to protect skin from free radical. Lavender oilwas a popular parfume of cosmetic form because of its antioxidant dan sunscreen activity. Body butter form was needed to increase antiaging activity of lavender oil. The study aimed to evaluate antiaging activity of lavender body butter trough antioxidant and sunscreen activity evaluation. Body butter was made from combination of lavender oil, olive oil, coconut oil beside cocoa butter. DPPH method was used to evaluate antioxidant activity, sunscreen activity was evaluated of the Sun Protection Factor value (SPF), the percentage of erythema transmission (%Te) and percentage of pigmentation (% Tp). The study showed that the body butter formula had IC50 of 56,34 ppm, 6,68 of %Te, 16,34 of %Tp and the SPF value was 10,88. The formula can increase lavender oil’s antioxidant and sunscreen activity and it was need the addition of chemical sunscreen compound such as Zinci Oxyde or Titanium Oxyde. It can concluded body butter had strong antioxidant activity. It can protect the skin to againt UVA ray but less protect from UVB and UVC rays.

Perilaku Mahasiswi Dalam Perawatan Kecantikan Secara Tradisional Indarto A S; Nutrisia Aquariushinta Sayuti; Atik Riwati
Jurnal Kebidanan dan Kesehatan Tradisional Vol 1 No 1 (2016): Jurnal Kebidanan dan Kesehatan Tradisional
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkkt.v1i1.44

Abstract: Behavior, Young Women, Traditional Beauty Care. This study aims to reveal the behavior of a student in a traditional beauty treatments. This study used a qualitative design with sampling technique is purposive sampling and the type of maximum variation sampling. Collecting data using Focus Group Discussion and Interview depth. This study uses 6 informant DKT and 2 informants WM. Test the validity of the data was done by using triangulation. The results showed that most informants understand the sense of beauty treatments and traditional, benefits and problems on the part of the body, the informant also shows a good attitude to the traditional beauty treatments, and the attitude of informants in beauty treatments traditionally reaches levels responsible attitude. Activity informant in beauty treatments has traditionally been reached on the level of activity adoption.

Pengaruh Carboxymethyl Celulosa Natrium Sebagai Pengental Terhadap Stabilitas Sirup Temulawak (Curcuma Xanthorriza Roxb) Nutrisia Aquariushinta Sayuti
Jurnal Kebidanan dan Kesehatan Tradisional Vol 1 No 1 (2016): Jurnal Kebidanan dan Kesehatan Tradisional
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jkkt.v1i1.53

Abstract : Carboxymethyl celulosa natrium, Curcuma xanthorriza Roxb syrup, Stability. The lack flavor and amylum contain of Curcuma xanthorriza Roxb cause difficulty to make it in to syrup. Carboxymethyl Celulose Natrium (CMC- Na) as a thickener was needed to solve the problem. The study aim to determine the influence of CMC-Na to syrup’s stability Curcuma xanthorriza. The methode was used to determine stability of syrup formulation with three formula with variations in the amount of 1% CMC-Na solution and 80% sucrose solution. Physical stability parameter of the syrup such as viscosity, acidity and organoleptic analyzed by two way anava. The result showed that CMC-Na effected on viscosity, acidity and organoleptic of the syrup. There are influence of CMC-Na to syrup’s stability.

Formulasi dan Uji Stabilitas Fisik Sediaan Gel Ekstrak Daun Ketepeng Cina (Cassia alata L.) Nutrisia Aquariushinta Sayuti
Jurnal Kefarmasian Indonesia VOLUME 5, NOMOR 2, AGUSTUS 2015
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v5i2.3500

Cassia alata L. leaf contains flavonoids which have anti-inflammatory, anti-allergy, antioxidants and antifungal effects. The traditional application of it requires long preparation time so we need a formulation with more practical and durable storage is needed. Gel formulation was chosen because it is easy to dry, forming an easy to wash film layer and give a sense of cold on the skin. Gel components affect the stability of the gel. Physical stability is analyzed to ensure that the formulated gel’s quality, safety and benefits meet the specifications and survive during storage. This study aimed to create a gel formula and analysed its physical stability test of Cassia alata L. leaf extract gel. Research design adopted in this study was an experimental laboratory. Optimum gel formula determined by variations in the concentration of sodium carboxymethyl celulose (CMCNa). Gel that meet the criteria of homogeneity, consistency, pH and spreadibility was set as the optimum formula. Physical stability of optimum formula was analyzed by organoleptic, homogeneity test, pH test, viscosity test and spredability test. Gel that meets the acceptance criteria are Cassia alata L. leaf extract gel with CMC-Na concentration of 3% those determined as the optimum formula. Stability analysis of optimum formula didn’t show any changes in pH, color, smell and taste, although it changes of the shape, viscosity and spreadibility were found. The optimum formula gel obtained by the concentration of CMC-Na 3%. results were less stable during the 8 weeks of storage at a temperature of 40°C.

RESPON RASA CAMPURAN EKSTRAK SELEDRI (Apium graveolens L.) DAN EKSTRAK ASAM JAWA (Tamarindus indica L.) DALAM SEDIAAN SERBUK EFFERVESCENT Nutrisia Aquariushinta Sayuti
Jurnal Farmasi Indonesia Vol 12 No 2 (2015): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

The research aimed to determine effervescent powder formula with concentration variation of Celery extract and Tamarind extracts to the taste aspects of the best. The research was a quasi-experimental design with one shot case study. The evaluation was done to three formula with combination of celery extract and tamarind extract 50%:50% (formula A), 75%:25% (formula B), and 25%:75% (formula C). Physical test was conducted on the organoleptic, moisture content, flow rate, angle of repose and time dispersion of formula. Hedonic test performed to assess the response of the resulting flavor. Respondents of hedonic test was 54 students of Jamu Department, Health Polytechnic Surakarta. The results showed that the different combinations of extract affected to color, aroma and taste parameter of organoleptic results and time dispersion. 61% of respondents liked the flavor of formula C. The flavor of formula A and B was favored by 45% of respondents for each formula. The conclusion was there were no differences of taste respons in the hedonic test results because of differences in theconcentration of combination of celery extract and tamarind extract in effervescent powder formula with p = 0.423 (p> 0.05)

PENGARUH PENYULUHAN TERHADAP PENINGKATAN PENGETAHUAN TENTANG PERAWATAN ORGAN INTIM DENGAN TANAMAN JAMU PADA REMAJA PUTRI DI SMA N 1 JATINOM Nutrisia Aquariushinta Sayuti; Nancy Anita Nirwana Sari
Jurnal Kebidanan Indonesia Vol 6, No 2 (2015): JULI
Publisher : STIKES Mamba'ul 'Ulum Surakarta

Pengetahuan tentang perawatan organ intim yang baik merupakan faktor penentu dalam memelihara kesehatan reproduksi. Masalah yang timbul akibat kurangnya pengetahuan tentang perawatan organ intim yaitu bau tidak sedap dan lendir berlebihan pada vagina serta keputihan. Berdasarkan studi pendahuluan, 7 dari 10 siswi SMA N 1 Jatinom tidak mengetahui bagaimana cara merawat organ intim dengan tanaman jamu. Tujuan penelitian ini adalah mengetahui pengaruh penyuluhan terhadap peningkatan pengetahuan remaja putri tentang perawatan organ intim dengan tanaman jamu. Penelitian ini menggunakan metode rancangan eksperimen semu (quasi experiment design). Teknik pengambilan sampel yang digunakan adalah teknik purposive sampling. Pengumpulan data menggunakan kuesioner yang dilakukan dua kali yaitu pretest dan posttest. Hasil penelitian menunjukkan bahwa pengetahuan remaja putri meningkat sebesar 14,97 (19,66%) dengan nilai p=0,000 (p

The Effectiveness of Zoledronic Acid and Ibandronic Acid in Delaying Skeletal-Related Events in Multiple Myeloma in Indonesia Nutrisia Aquariushinta Sayuti; Tri Murti Andayani; Dwi Endarti; Kartika Widayati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 10, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.55943

Zoledronic acid and ibandronic acid are listed in the Indonesian national formulary to prevent skeletal-related events (SRE) in patients diagnosed with bone metastasis in multiple myeloma (MM), with limited evidence to compare their effectiveness. This study aimed to investigate the effectiveness and safety of zoledronic acid and ibandronic acid in delaying SRE. The method was the retrospective, with data obtained from the multicenter study for MM patients with bone metastasis (aged over 18 years), based on medical records between January 2016 and December 2018. Patients were assigned to zoledronic acid and ibandronic acid groups. The clinical outcome was the next SRE which consists of vertebral/bone fracture, spinal cord compression leading to the need for surgery or radiation, and adverse event (AE) due to 2 years of drugs usage. Result of this research was made up of a total of seventy (70) patients with 40 in the zoledronic acid group, and 30 in ibandronic acid. At median treatment duration of 8 months (range: 2 – 24 month), SRE incident in zoledronic acid and ibandronic acid were 20.0 % and 23.3 % respectively. Furthermore, their mean SRE free survival times were 21 months [95% confidence interval (CI) 19 - 23 months], and 19 months [95% CI, 16 – 22 months], respectively. Also, their time intervals were not significantly different (p>0.05). The osteonecrosis of the jaw (ONJ) was AE which occurred more in zoledronic acid than ibandronic acid. The conclusion was zoledronic acid tends to delay SRE time compared to ibandronic acid, although more ONJ occur.

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