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All Journal Jurnal Surya Medika Medical Sains : Jurnal Ilmiah Kefarmasian
Insyira Fadliana Basri
Poltekkes Kemenkes Gorontalo
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Tingkat Pengetahuan, Sikap dan Rasionalitas Swamedikasi pada Masa Pandemi di Kota Gorontalo Vyani Kamba; Prisca Safriani Wicita; Insyira Fadliana Basri; Pratiwi Y Ishak
Jurnal Surya Medika (JSM) Vol 8 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3248

Abstract

Changes in people's lifestyles tend to pay less attention to health, and the development of diseases in the community is also unavoidable, especially during the current Covid-19 pandemic. The development of this disease encourages people to look for alternative treatments that are cost-effective and therapeutically effective. In this regard, self-medication or self-medication is an alternative that is taken by the community. Community efforts to treat themselves are known as self-medication or self-medication. This study aims to determine the knowledge, attitudes, and rationality of self-medication in the community in Gorontalo City with a descriptive cross-sectional design method. The sample in this study were people who did self-medication and met the inclusion criteria, namely aged 18-60 years and willing to be respondents as many as 80. The level of knowledge related to self-medication of the people of Gorontalo City is 43.8% in the good category, self-medication attitude in a good category is 55%, and rationality is 65%. There is a significant relationship between respondents' knowledge level and self-medication attitude, with a p-value of 0.001.
Tingkat Pengetahuan, Sikap dan Rasionalitas Swamedikasi pada Masa Pandemi di Kota Gorontalo: Patient Knowledge, Attitude and Rationality of Self-Medicatio During Pandemic in Gorontalo City Vyani Kamba; Prisca Safriani Wicita; Insyira Fadliana Basri; Pratiwi Y Ishak
Jurnal Surya Medika (JSM) Vol. 8 No. 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3248

Abstract

Changes in people's lifestyles tend to pay less attention to health, and the development of diseases in the community is also unavoidable, especially during the current Covid-19 pandemic. The development of this disease encourages people to look for alternative treatments that are cost-effective and therapeutically effective. In this regard, self-medication or self-medication is an alternative that is taken by the community. Community efforts to treat themselves are known as self-medication or self-medication. This study aims to determine the knowledge, attitudes, and rationality of self-medication in the community in Gorontalo City with a descriptive cross-sectional design method. The sample in this study were people who did self-medication and met the inclusion criteria, namely aged 18-60 years and willing to be respondents as many as 80. The level of knowledge related to self-medication of the people of Gorontalo City is 43.8% in the good category, self-medication attitude in a good category is 55%, and rationality is 65%. There is a significant relationship between respondents' knowledge level and self-medication attitude, with a p-value of 0.001.
AKTIVITAS ANTIOKSIDAN DAN KANDUNGAN TOTAL FENOLIK PADA EKSTRAK TERIPANG (Holothroidea): ANTIOXIDANT ACTIVITY AND TOTAL PHENOLIC COMPOUNDS OF SEA CUCUMBER (Holothroidea) EXTRACT Fadli Husain; Fitriah Ayu Magfirah Yunus; Insyira Fadliana Basri
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.665

Abstract

Radikal bebas adalah senyawa yang memiliki sifat reaktif. Senyawa ini mudah bereaksi dengan molekul lain dengan cara mengoksidasi sehingga dapat menimbulkan pengaruh negatif terhadap tubuh antara lain mengakibatkan kerusakan lipida, protein, DNA dan membran sel. Adanya radikal bebas menyebabkan tubuh membutuhkan zat penting yang dapat menangkap radikal bebas, yaitu antioksidan. Senyawa antioksidan merupakan zat yang dapat mencegah terjadinya proses oksidasi. Teripang merupakan salah satu produk laut yang memiliki aktivitas antioksidan. Senyawa yang terdapat pada teripang telah dibuktikan secara ilmiah dapat meredam radikal bebas yang menyebabkan berbagai penyakit degeneratif. Beberapa senyawa diantaranya adalah triterpen glikosida (saponin), kondroitin sulfat, glycosaminoglycans (GAGs), fenolik, dan asam lemak esensial. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dan kandungan fenolik total dalam ekstrak teripang yang berasal dari perairan Patoameme Kab. Boalemo Gorontalo. Penelitian ini merupakan jenis penelitian eksperimental laboratorium yang akan dilaksanakan di Gorontalo dan Makassar. Hasil yang didapatkan bahwa ekstrak etanol teripang mengandung senyawa fenol dan flavonoid, serta hasil pengujian aktivitas antioksidan yang diuji dengan metode ABTS, BCB, dan DPPH menunjukkan hasil IC50 berturut-turut yaitu 91,4 µg/mL, 152,91 µg/mL, 233,6 µg/mL. Sedangkan pada metode FRAP menunjukkan bahwa ekstrak etanol teripang memiliki kemampuan dalam mereduksi besi sebesar 7,629±0,10 QEAC/g ekstrak.  Kata kunci : teripang, antioksidan, fenolik, DPPH
Co-Authors Fadli Husain Fitriah Ayu Magfirah Yunus Pratiwi Y Ishak PRISCA SAFRIANI WICITA Vyani Kamba