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All Journal JURNAL ILMU KEFARMASIAN INDONESIA Journal of Experimental and Clinical Pharmacy (JECP) Medical Sains : Jurnal Ilmiah Kefarmasian Journal Nursing Care Jurusan Keperawatan Politeknik Kesehatan Gorontalo IICSDGs Jurnal Katalisator

Fadli Husain

Jurusan Farmasi Politeknik Kesehatan Kementerian Kesehatan Gorontao

Author-ID : 3371416

Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Analisis Pengelolaan Obat di Instalasi Farmasi Dinas Kesehatan Kabupaten/Kota Se-Provinsi Gorontalo Periode Tahun 2018 dan 2019 Fadli Husain; Vyani Kamba; Zulfiayu Zulfiayu; Arlan K Imran
Journal of Experimental and Clinical Pharmacy (JECP) Vol 2, No 1 (2022): Februari 2022
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v2i1.352

Instalasi farmasi sering menghadapi permasalahan pada tahap seleksi, perencanaan dan pengadaan. Pengelolaan obat yang buruk menyebabkan tingkat ketersediaan obat menjadi berkurang, terjadi kekosongan obat, banyaknya obat yang menumpuk karena tidak sesuainya perencanaan obat, serta banyaknya obat yang kadaluwarsa/rusak akibat sistem distribusi yang kurang baik sehingga dapat berdampak kepada inefisiensi penggunaan anggaran/biaya obat di tingkat Kabupaten/Kota. Penelitian ini menggunakan rancangan deskriptif dengan pengambilan data secara retrospektif dan concurent. Penelitian ini dilaksanakan di Instalasi Farmasi Kab. Kota se-Provinsi Gorontalo. Alat ukur penelitian ini adalah daftar pertanyaan berdasarkan indikator standar yang telah ditetapkan sesuai pedoman yang digunakan untuk monitoring dan evaluasi pengelolaan obat kabupaten/kota, serta melakukan wawancara langsung kepada penanggung jawab Instalasi Farmasi setempat. Hasil penelitian didapatkan bahwa; alokasi dana pengadaan obat tahun 2018 > 2 Miliar rupiah dan tahun 2019 1,7 Miliar - 4,3 Miliar rupiah. Terdapat 50% Kabupaten/kota yang sudah memiliki Tim Perencanaan Obat Terpadu (TPOT) di lingkungan Dinas Kesehatan. Biaya obat perkapita bila menggunakan standar WHO 1 US$ perkapita maka 80% Kabupaten/Kota sudah sesuai bahkan melampaui, hanya 1 kabupaten yang dibawah standar WHO. Terdapat 83% Kabupaten/kota yang kesesuaian item obat dengan DOEN diatas 80% dan seluruh Kabupaten Kota mempunyai kesesuaian FORNAS lebih dari 80%.Pharmaceutical installations often face problems at the selection, planning, and procurement stages. Poor drug management causes decreasing the level of drug availability, drug vacancies, overstock of drugsdue to inappropriate drug planning, and expired/damaged drugs due to a poor distribution system can have an impact on inefficiency in the use of drug budgets/costs at the Regency/City. This study used a descriptive design with retrospective and concurrent. This research was conducted at the Pharmacy Installation at the Regency/City in Gorontalo Province. The measuring instrument for this research is a list of questions based on standard indicators that have been set according to the guidelines used for monitoring and evaluating regency/citydrug management and conducting direct interviews with the PIC of the local Pharmacy Installation. The results of the study found that; the allocation of funds for drug procurement in 2018 was more than 2 billion rupiah and in 2019 was 1.7 billion - 4.3 billion rupiah. There are 50% of regencies/cities already have an Integrated Drug Planning Team (TPOT) within the Health Office. Drug costs per capita when using the WHO standard of US$ 1 per capita, 80% of districts/cities comply and even exceed, only 1 district is below the WHO standard. There are 83% of regencies/cities whose conformity of drug items with DOEN is above 80% and all regencies/cities have FORNAS conformity of more than 80%.

Uji Aktivitas Antioksidan Sediaan Lip Balm Rambut Jagung (Zea mays L.) dengan Metode DPPH (1,1-Diphenyl-2-Picrylhydrazyl) Hartati Hartati; Fadli Husain; Nangsih Sulastri Slamet; Fihrina Mohamad; Zulfiayu Sapiun
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 2 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.829

Jagung sebagai komoditas utama di Provinsi Gorontalo menghasilkan limbah yang cukupbanyak. Hal ini membuat pemerintah menawarkan peluang investasi dengan memanfaatkan limbahjagung, di antaranya rambut jagung. Studi pustaka menunjukkan bahwa rambut jagung memilikiaktivitas antioksidan yang cukup baik, sehingga dilakukan formulasi lip balm dengan memanfaatkaninfusa rambut jagung sebagai bahan aktif. Penelitian kuantitatif dengan quasi eksperimen laboratoriumdilakukan untuk mengetahui aktivitas antioksidan dari sediaan lip balm rambut jagung (Zea mays L.)yang diformulasi dengan menggunakan tiga konsentrasi infusa rambut jagung, yaitu Formula A (7,5%);Formula B (15%) dan Formula C (22,5%). Sediaan dibuat dengan mencampurkan fase air (infusa rambutjagung dan gliseril monostearat) dengan fase minyak (lanolin, beeswax, setil alkohol, paraffi n cair danminyak jagung) serta emulgator (span 60 dan tween 60). Hasil uji stabilitas organoleptik dan pH selama4 minggu pengamatan menunjukkan bahwa tidak ada perubahan, baik dari segi organoleptik maupunpH masing-masing sediaan. Aktivitas antioksidan diukur dengan menggunakan spektrofotometer UVVisibel“SHIMADZU UV-1800” dan kuersetin (1000 μg/mL) sebagai pembanding. Hasil pengujianmenunjukkan bahwa Formula B (15%) memberikan aktivitas yang lebih baik dalam meredam radikalDPPH dengan nilai IC50 sebesar 0,987 mg/mL, Formula C (22,5%) sebesar 1,857 mg/mL dan FormulaA (7,5%) sebesar 2,909 mg/mL.

Kompres Hangat Dan Kompres Jahe Terhadap Penurunan Skala Nyeri Pada Pasien Rematik Ratnawati Ratnawati; Fadli Husain; Farman Biki
Journal Nursing Care Jurusan Keperawatan Politeknik Kesehatan Gorontalo Vol 6, No 2 (2020): JOURNAL NURSING CARE
Publisher : Poltekkes Kemenkes Gorontalo

Background: Rheumatic disease is a chronic systemic inflammatory disease in the joints of the body, which has clinical symptoms in the form of joint pain disorders accompanied by stiffness, redness, and swelling and is chronic. One of the treatments to deal with pain is by stimulating heat on the part of the body that is experiencing pain, including by giving warm compresses and ginger compresses which can have a warm effect on the body. Objective: This study aims to identify differences in the effectiveness of warm compresses and ginger compresses on reducing pain scale in rheumatic patients.Methods: This study uses a quasi-experimental design method with a non-equivalent control group design. The sampling technique used is quota sampling. The number of samples studied were 40 respondents, who were divided into two treatment groups. The first group was given a warm compress treatment and the second group was given a ginger compress treatment.Results: The results of the study and analysis using the Independent T-Test statistical test with a significance degree of : 0.05. The results showed that the p-value was 0.024, so H0 was rejected.Conclusion: Based on the results of the study, it can be concluded that there are differences in the effectiveness of warm compresses and ginger compresses on reducing pain scale in rheumatic patients where ginger compresses are more effective than warm compresses with an average difference of 1.25 pain scale.

Hidroterapi Rendam Air Hangat Lombongo Terhadap Penurunan Tekanan Darah Pada Penderita Hipertensi Ratnawati Ratnawati; Fadli Husain; Farman Biki
Journal Nursing Care Jurusan Keperawatan Politeknik Kesehatan Gorontalo Vol 7, No 1 (2021): JOURNAL NURSING CARE
Publisher : Poltekkes Kemenkes Gorontalo

Background: Hypertension can be defined as abnormally high blood pressure. One of the recommended treatment measures is through hydrotherapy using water with a temperature not exceeding 37-37.50CObjective: This study aims to determine the effect of blood pressure before and after warm water bath hydrotherapy in patients with hypertensionMethod: quasi-experimental with one group pretest-posttest approach. The population is all people who experience hypertension recorded in the working area of the South Suwawa Health Center, amounting to 150 people with purposive sampling technique so that the number of samples is 30 people.Results: The results showed that after five weeks of treatment there was an effect on blood pressure of hypertensive patients as evidenced by a significant value of 0.000, 0.05 with an average number of hypertensive patients who experienced a decrease in blood pressure, namely 13 people (43.5%).Conclusion: there is an effect of hydrotherapy soaked in warm water of Lombongo on reducing blood pressure in patients with hypertension.

Aktivitas Antimikroba Sabun Antiseptik Bunga Eceng Gondok (Eichhornia crassipes) dengan Basis Minyak Jelantah Nangsih Sulastri Slamet; Fihrina Mohamad; Hartati Hartati; Fadli Husain; Zulfiayu Sapiun
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 2 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i2.1078

Water hyacinth flowers (Eichhornia crassipes) contain antibacterial phenols, flavonoids, alkaloids, tannins, terpenoids, sterols, and glycosides that can be made into antiseptic soaps. Used cooking oil purifi ed with banana peel can be used to make soap. This study aimed to determine how to process used cooking oil, formulate and test antimicrobial antiseptic soaps using water hyacinth flower extract. The method uses antiseptic soap formulated with 10%, 15%, and 20% water hyacinth infusion. Physical, chemical, irritation, and antibacterial testing of the preparation. Used cooking oil is refined and clear, not thick. Water hyacinth flower extract can be formulated into antiseptic soap with a 1.5 cm foam height, cleaning power in criteria 3, pH in the range 9-10, water content >15%, and free alkali content of 0.6- 1.3%. Formula A (19.17 mm), B (20.01 mm), and C have strong antibacterial activity against E. coli based on the diameter of the barrier (20.13 mm). Water hyacinth flower extract and used cooking oil can be used to make antimicrobial antiseptic soap.

QUALITY OF LIFE IN PATIENTS WITH HYPERTENSION INPUBLIC HEALTH CENTER SIPATANA GORONTALO CITY USING WHOQOL-Breff QUESTIONNAIRE Fadli Husain
International Interdisciplinary Conference on Sustainable Development Goals Vol 2 No 1 (2019): Proceedings of International Interdisciplinary Conference on Sustainable Developm
Publisher : LP2M Universitas Bina Mandiri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (487.082 KB)

WHO (2011) notes that one billion people in the world suffer from hypertension and cause nearly 8 million deaths each year worldwide and nearly 1.5 million people each year in Southeast Asia. Basic Health Research (Riskesdas) in 2013 revealed the incidence of hypertension in Indonesia Reached around 25.8%. This study aims to Determine what factors are related to the quality of life of Hypertensive Patients as measured using the WHOQOL-BREF questionnaire. This research was conducted in the working region of Sipatana Health Center, Gorontalo City with the research method used was descriptive method with cross-sectional design. The research measuring instrument uses the World Health Organization Quality of Life (WHOQOL) -Bref Questionnaire, questionnaire consisting of 26 questions and is divided into four domains items, namely the domain of physical, psychological, social and environmental health quality and conducted by interviewing Patients who are being Examined health at the Sipatana Health Center. The description of the factors related to the quality of life of Hypertensive Patients at the Sipatana Health Center is Described as follows: Education Level Factors, based on the results of the study show that respondents with low education growing niche to have a poor quality of life as much as 66%. Occupational Factor. In this study, the majority of Hypertensive Patients who did not work / work did not have a poor quality of life, as many as 30 respondents (60%). Then the Joint Living Factor, based on the Chi-square statistical test, P = 0:15 Obtained a value indicating that there was no significant relationship between Hypertensive Patients with the main family living and quality of life. Finally.

SUPLEMENTASI SARI DAUN KELOR (Moringa oleifera L.) MENURUNKAN BILANGAN PEROKSIDA DAN ASAM LEMAK BEBAS VCO Nangsih Sulastri Slamet; Ghaitsa Zahira Sopha Yusuf; Fadli Husain; Fihrina Mohamad; Prisca Safriani Wicita; Zulfiayu; Fitriah Ayu Maghfirah Yunus
JURNAL KATALISATOR Vol. 8 No. 1 (2023): Jurnal Katalisator Volume 8 No. 1, April 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Syarat VCO menurut SNI 7381:2008 yaitu memiliki nilai bilangan peroksida dan kadar asam lemak bebas yang rendah. Permasalahan VCO yang beredar saat ini yaitu pada parameter organoleptik khususnya pada aroma bau tengik yang mempengaruhi kualitas dan penyimpanan. Sehingga untuk mengatasi hal tersebut diperlukan antioksidan alami. Daun kelor merupakan tanaman yang berpotensi sebagai antioksidan alami, sehingga berpotensi dalam menurunkan bilangan peroksida dan asal lemak bebas pada VCO.Penelitian ini bertujuan mengetahui nilai bilangan peroksida dan asam lemak bebas pada VCO yang disuplementasi dengan sari daun kelor (Moringa oleifera L.) menggunakan metode fermentasi.Penelitian ini merupakan penelitian quasi eksperimen mengunakan rancangan acak lengkap (RAL) dengan 4 formulasi dengan variasi volume penambahan sari daun kelor F1 (0 mL); F2 (50 mL); F3 (100 mL) dan F4 (150 mL). Bilangan peroksida dan asam lemak bebas dianalisis menggunakan metode titrimetri. Analisis data menggunakan uji Kruskal Wallis dan dilanjutkan dengan uji Mann Whitney.Hasil Penelitian: penambahan sari daun kelor dapat menurunkan bilangan peroksida dan asam lemak bebas pada VCO yang dihasilkan. Bilangan peroksida terukur pada F1, F2, F3 dan F4 berturut-turut adalah 5,76; 3,33; 2,42 dan 1,82 meq/kg, sedangkan kadar asam lemak bebas terukur berturut-turut sebesar 0,4; 0,36; 0,31 dan 0,2 %.Kesimpulan: Semakin besar volume sari daun kelor yang ditambahkan maka nilai bilangan peroksida dan kadar asam lemak bebas pada VCO semakin rendah.

AKTIVITAS ANTIOKSIDAN DAN KANDUNGAN TOTAL FENOLIK PADA EKSTRAK TERIPANG (Holothroidea): ANTIOXIDANT ACTIVITY AND TOTAL PHENOLIC COMPOUNDS OF SEA CUCUMBER (Holothroidea) EXTRACT Fadli Husain; Fitriah Ayu Magfirah Yunus; Insyira Fadliana Basri
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.665

Radikal bebas adalah senyawa yang memiliki sifat reaktif. Senyawa ini mudah bereaksi dengan molekul lain dengan cara mengoksidasi sehingga dapat menimbulkan pengaruh negatif terhadap tubuh antara lain mengakibatkan kerusakan lipida, protein, DNA dan membran sel. Adanya radikal bebas menyebabkan tubuh membutuhkan zat penting yang dapat menangkap radikal bebas, yaitu antioksidan. Senyawa antioksidan merupakan zat yang dapat mencegah terjadinya proses oksidasi. Teripang merupakan salah satu produk laut yang memiliki aktivitas antioksidan. Senyawa yang terdapat pada teripang telah dibuktikan secara ilmiah dapat meredam radikal bebas yang menyebabkan berbagai penyakit degeneratif. Beberapa senyawa diantaranya adalah triterpen glikosida (saponin), kondroitin sulfat, glycosaminoglycans (GAGs), fenolik, dan asam lemak esensial. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dan kandungan fenolik total dalam ekstrak teripang yang berasal dari perairan Patoameme Kab. Boalemo Gorontalo. Penelitian ini merupakan jenis penelitian eksperimental laboratorium yang akan dilaksanakan di Gorontalo dan Makassar. Hasil yang didapatkan bahwa ekstrak etanol teripang mengandung senyawa fenol dan flavonoid, serta hasil pengujian aktivitas antioksidan yang diuji dengan metode ABTS, BCB, dan DPPH menunjukkan hasil IC50 berturut-turut yaitu 91,4 µg/mL, 152,91 µg/mL, 233,6 µg/mL. Sedangkan pada metode FRAP menunjukkan bahwa ekstrak etanol teripang memiliki kemampuan dalam mereduksi besi sebesar 7,629±0,10 QEAC/g ekstrak. Kata kunci : teripang, antioksidan, fenolik, DPPH

Co-Authors Farman Biki Fihrina Mohamad Fitriah Ayu Magfirah Yunus Fitriah Ayu Maghfirah Yunus Ghaitsa Zahira Sopha Yusuf Hartati Hartati Imran, Arlan K Insyira Fadliana Basri Nangsih Sulastri Slamet PRISCA SAFRIANI WICITA Ratnawati Ratnawati Ratnawati Ratnawati Sapiun, Zulfiayu Vyani Kamba

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