Ali Budi Harsono
Departemen Obstetri dan Ginekologi Fakultas Kedokteran Universitas Padjadjaran/ RSUP Dr. Hasan Sadikin Bandung

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Gambaran Klinis dan Histopatologi Kanker Ovarium di RSUP Dr. Hasan Sadikin Bandung Tahun 2019-2020 Salfa Aqilla; Ali Budi Harsono; Hasrayati Agustina
Indonesian Journal of Obstetrics & Gynecology Science Volume 5 Nomor 1 Maret 2022
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v5n1.363

Abstract

Tujuan: Penelitian ini bertujuan untuk mengetahui gambaran klinis dan histopatologi pasien kanker ovarium di RSHS tahun 2019-2020. Metode: Penelitian deskriptif ini dilaksanakan di RSUP Dr. Hasan Sadikin Bandung dengan menggunakan data rekam medis pasien kanker ovarium yang didiagnosis secara histopatologi tahun 2019-2020. Sampel dipilih menggunakan metode total sampling. Hasil: Penelitian ini menunjukan dari 140 pasien, mayoritas berusia 46-55 tahun (31,4%), multipara (60,7%), dan IMT normal (57,1%). Pasien mayoritas mengeluhkan adanya benjolan pada abdomen (100%) dengan karakteristik kistik sebagian padat (51,4%), berbenjol (57,1%), unilateral (87,4%), dan immobile (35,0%). Kebanyakan pasien memiliki nilai haemoglobin (75,3%) dan albumin (20,7%) rendah. Tumor marker yang paling sering ditemukan adalah CA 125 (37,9%). Mayoritas pasien didiagnosis pada stadium III (47,1%), tipe histopatologi mucinous carcinoma (20,0%) dan dilakukan operasi complete surgical staging (46,8%).Kesimpulan: Pasien kanker ovarium tahun 2019-2020 terbanyak adalah pada usia 46-55, multipara, IMT normal, mengeluhkan massa pada abdomen dengan karakteristik kistik sebagian padat, berbenjol, unilateral. Umumnya pasien mengalami penurunan nilai haemoglobin dan albumin serta berada pada stadium III dengan tipe histopatologi mucinous carcinoma dan dilakukan operasi complete surgical staging.Clinical Features and Histopathology of Ovarian Cancer at RSUP Dr. Hasan Sadikin Bandung 2019-2020AbstractObjective: This study aimed to determine the clinical and histopathological features of ovarian cancer patients at Hasan Sadikin General Hospital Bandung 2019-2020.Method: This descriptive research was conducted at Hasan Sadikin General Hospital Bandung using medical record data for ovarian cancer patients diagnosed histopathologically in 2019-2020. The sample was selected using the total sampling method. Results: This study showed that from 140 patients, the majority were aged 46-55 years (31.4%), multiparous (60.7%), and normal BMI (57.1%). The majority of patients complained of a lump in the abdomen (100%) with the characteristics of a cyst with partially solid (51.4%), uneven surface (57.1%), unilateral (87.4%), and immobile (35.0%). Most patients had low hemoglobin (75.3%) and albumin (20.7%) values. The most common tumor marker found was CA 125 (37.9%). The majority of patients were in stage III (47.1%), the histopathological type of mucinous carcinoma (20.0%), and underwent complete surgical staging (46.8%).Conclusion: Most ovarian cancer patients in 2019-2020 were aged 46-55, multiparous, normal BMI, complained of a mass in the abdomen with the characteristics of a cyst with partially solid,uneven surface, unilateral. Generally, patients have decreased hemoglobin and albumin values were diagnosed as stage III, the histopathological type of mucinous carcinoma and underwent complete surgical staging.Key words: ovarian cancer, clinical features, histopathology
Karakteristik Karsinoma Ovarium Pra-Menopause dengan Kadar CA 125 ≤200 U/mL di RSUP Dr. Hasan Sadikin Bandung dari Tahun 2019–2021 Yudi Mulyana Hidayat; Eunike Febe Febriani; Ali Budi Harsono; Gatot N. A. Winarno; Andi Kurniadi
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 2 Juli 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6.n2.491

Abstract

Tujuan: Mendeskripsikan karakteristik karsinoma ovarium pra-menopause dengan kadar CA 125 ≤ 200 U/mL di RSUP Dr. Hasan Sadikin Bandung dari tahun 2019 sampai 2021.Metode: Penelitian deskriptif ini menggunakan metode total sampling dari data sekunder pasien kanker ovarium yang memenuhi kriteria inklusi dan memiliki variabel lengkap.Hasil: Penelitian yang melibatkan 32 sampel ini, menunjukkan nilai rata-rata CA 125 sebesar 82,63 U/mL dengan interval 3,3–194,8 U/mL. Mayoritas pasien berada pada rentang usia 40–49 tahun (40,6%), sudah menikah (87,5%), berprofesi sebagai ibu rumah tangga (81,3%), dan tinggal di Kawasan Pembangunan Bandung Raya (34,4%). Sebanyak 37,5% pasien adalah nullipara dan memiliki tipe histopatologis tumor epitel mucinous. Stadium tumor terbanyak adalah stadium I (56,3%). Kebanyakan pasien menjalani surgical staging komplit sebagai terapi penyakitnya (46,8%). Kesimpulan: Sebagian besar pasien karsinoma ovarium pra-menopause dengan kadar CA 125 ≤ 200 U/mL pada tahun 2019–2021 berada pada rentang usia 40–49 tahun, sudah menikah, bekerja sebagai ibu rumah tangga, dan berdomisili di Kawasan Pengembangan Bandung Raya. Kebanyakan pasien berstatus nullipara, memiliki tumor dengan tipe histopatologis epitel mucinous, dan terdiagnosis pada stadium I. Tipe pengobatan yang paling umum ditemui adalah surgical staging komplit.Characteristics of Pre-Menopausal Ovarian Carcinoma with CA 125 Level ≤ 200 U/mL in Dr. Hasan Sadikin General Hospital Bandung From 2019–2021Abstract Objective: To describe the characteristics of pre-menopausal ovarian carcinoma patients with CA 125 Level ≤ 200 U/mL in Dr. Hasan Sadikin General Hospital Bandung from 2019 until 2021.Method: This descriptive study used the total sampling method of secondary data on ovarian cancer patients that have met the inclusion criterias and have complete variables.Results: This study involving 32 samples showed the average level of CA 125 was 82,63 U/mL with the interval of 3,3 – 194,8 U/mL. Majority of the patients were in the age range of 40 – 49 years old (40,6%), has been married (87,5%), were housewifes (81,3%), and lived in Development Area of Bandung Raya (34,4%). About 37,5% patients were nullipara and had mucinous epithelial histopatology type of tumor. The most abundant tumor stage were stage I (56,3%). Most patients had undergoing complete surgical staging for their therapy (46,8%). Conclusion: Most of pre-menopausal ovarian carcinoma patients with CA 125 level ≤ 200 U/mL  in 2019–2021 were in the age range of 40 – 49 years old, has been married, had profession as housewifes, and domiciled in Development Area of Bandung Raya. Majority of patients were nullipara, had tumor with mucinous epithelial histopatology type, and were diagnosed at the stage I. The most found therapy were complete surgical staging.Key words: ovarian cancer, CA 125, cancer antigen 125, characteristic