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All Journal Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Community Empowerment
Nawadhir Fauzan
Universitas Garut
Humanities Decision Sciences, Operations Research & Management Languange, Linguistic, Communication & Media Medicine & Pharmacology Social Sciences Other

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Digital Marketing Strategy for MSME Products 'Ketan Ma Adah Bagendit' by Utilizing Social Media Firman Nur Hakim; Abda Fillah Al Intifadha; Agni Triwulansari; Ahmad Yusron Sidik; Aliefa Bintan Karamy; Elsa Zulfiah; Aam Munawar; Gita Anggaeni Permana; Imas Kurniati; Mohamad Rifki Nawawi; Nabila Yuniawati; Nawadhir Fauzan; Neneng Lisna Rahayu Sidiq; Rifa Fardila Arti; Rizki Insani Saputra; Romi Fikriawan Agusty; Wiwit Nursafitri; Nizar Alam Hamdani
Indonesian Journal of Community Empowerment (IJCE) Vol 2 No 03 (2021): Indonesian Journal of Community Empowerment (August)
Publisher : Fakultas Kewirausahaan Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35899/ijce.v2i03.445

Abstract

Abstract This community service has a purpose or work program to provide motivation or education about the importance of digital marketing at this time. The method used is in the form of socialization and data collection of SMEs in Bagendit village which allows for assistance in Digital Marketing. The socialization was carried out by coming to a recitation event in each citizens association and then giving a lecture about the importance of Digital Marketing. Then the data collection was carried out after the lecture by having a dialogue with the mothers who were present at the recitation. The results of this dedication to a work program are expected to be more productive on a daily basis, besides that it is also expected to be able to apply this digital marketing to SMEs owned so that they are more widely known. Abstrak Pengabdian kepada masyarakat Kelompok 1 ini memiliki tujuan atau program kerja untuk memberikan motivasi atau edukasi tentang pentingnya Digital Marketing pada saat sekarang ini. Metode yang digunakan berupa sosialisasi dan pendataan UMKM yang ada pada desa Bagendit yang memungkinkan untuk dibantu dalam Digital Marketingnya. Sosialisasi dilakukan dengan cara datang ke acara pengajian di setiap RW lalu memberikan ceramah tentang pentingnya Digital Marketing. Lalu untuk pendataan dilakukan sesudah ceramah dengan cara berdialog dengan ibu ibu yang hadir pada pengajian tersebut. Hasil dari pengabdian pada suatu program kerja ini diharapkan agar lebih bisa produktif dalam sehari harinya selain itu juga diharapkan dapat mengaplikasikannya digital marketing ini untuk UMKM yang dimiliki agar terkenal lebih luas.
In silico study: secondary metabolites from malay apple (Syzygium malaccense (L.) Merr. & L.M. Perry) as potential breast cancer treatments Riska Prasetiawati; Nawadhir Fauzan; Meilia Suherman
Pharmaciana Vol 13, No 3 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v13i3.26537

Abstract

Breast cancer has the highest prevalence of all cancers. Breast cancer has overtaken lung cancer as the leading cause of global cancer incidence in 2020, accounting for 2,261,419 new cases, or 11.7% of all new cancer cases worldwide. Among the efforts that can be done are efforts to find breast cancer medications that are safe and selective for the treatment and prevention of cancer, particularly those derived from medicinal plants. The Malay apple (Syzygium malaccense (L.) Merr. and L.M. Perry) is one plant that has been extensively examined and proved to have an antiproliferative effect. The pharmacophore modelling, molecular docking, and molecular dynamic approach was conducted on 155 active compounds of Malay apple to alpha and beta estrogen receptors. According on the results of ER-lamda docking, numerous substances have binding free energy values less than 4-OHT yet are not bound to important amino acids, as the result, it is not continued to the next test. On other side, with a fit score of 45.81, rutin was potentially selective for ER-beta receptors, molecular docking to ER-beta obtained that rutin was predicted to have breast cancer activity with a free binding energy value of -10.6 kcal /mol with better conformation and affinity compared to native ligand (genistein), and bound to essential amino acids as anticancer breast at ARG 346, GLU 305,  and molecular dynamics simulations show that the compound has good stability when binding to the receptor. In silico toxicity prediction from rutin showed outcomes that match the requirements for the candidate drug. However, because it does not match the ADME prediction and Lipinsky's rule of five, rutin must be optimalization to improve its pharmacokinetic and pharmacological profile before it can be further explored as a therapeutic option for the treatment of breast cancer that targets the ER- receptor.
Co-Authors Aam Munawar Abda Fillah Al Intifadha Agni Triwulansari Ahmad Yusron Sidik Aliefa Bintan Karamy Elsa Zulfiah Firman Nur Hakim Gita Anggaeni Permana Hamdani, Nizar Alam Imas Kurniati Meilia Suherman Mohamad Rifki Nawawi Nabila Yuniawati Neneng Lisna Rahayu Sidiq Rifa Fardila Arti Riska Prasetiawati Rizki Insani Saputra Romi Fikriawan Agusty Wiwit Nursafitri