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Clinical Profile Examination of Glucose, Uric Acid, and Cholesterol in Residents of Jatimulyo Village, Jember Philips Carel Perdana; Winitasha Alya Islami; Rizqy Aiddha Yuniawati; Nabilla Feirizky Chairunnisa; Qonita Pitra Larasati; Ali Akbar Haryanto; Adinda Fitria Nur Izzati; Renza Salwa Chintya; Syifa Kamila; Syeila Rahmadina; Aulia Rahman
Jurnal Pengabdian Masyarakat Bestari Vol. 1 No. 8 (2022): November 2022
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/jpmb.v1i8.1761

Abstract

Jember Regency is the area with the third highest population density in East Java Province, so the random blood sugar, uric acid, blood pressure, and cholesterol data obtained are able to reflect the real picture of Indonesian public health, especially in Jatimulyo Village. This study uses a prospective descriptive study, information about the patient's blood sugar, uric acid, and cholesterol profile is taken directly through a physical examination. The total data obtained from the health checks of Jatimulyo residents amounted to 26 residents. The results of the Jatimulyo residents' health checks which included blood sugar, uric acid, and cholesterol were mostly normal, while blood pressure was mostly found in the prehypertension categor
Effect of ethanol extract of Hedyotis corymbosa (L.) Lamk against parasitemia and hepatomegaly in Plasmodium berghei ANKA-infected mice Jelita Aprisano Putri; Nabilla Feirizky Chairunnisa; Heny Arwati; Hartono Kahar
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 1 (2023): Qanun Medika Vol 07 No 01 January 2023
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i1.15903

Abstract

Malaria is a parasitic infectious disease that remains one of the focuses of world health problems. The ethanol extract of Hedyotis corymbosa has biochemical compounds potentially become a new antimalarial drug. This study aimed to analyze the effect of this extract on parasitemia and hepatomegaly in mice infected with Plasmodium berghei ANKA. Twentyfive BALB/c mice were infected with P. berghei ANKA and grouped into 5 groups. Group 1-3 were treated with 250 mg/Kg BW (HC250), 300 mg/Kg BW (HC300), and 350 mg/Kg BW (HC350) of ethanol extract of H. corymbosa (EEHC), respectively. Group 4 was a positive control (POS) which was given dihydroartemisisnin-piperaquin (DHP) and Group 5 was a negative control (NEG) which was only given CMC Na 1%. Treatments were given orally once a day for four consecutive days. Parasitemia was observed daily on Giemsa-stained tail blood smear. On day 5 the mice were sacrificed, blood were collected by cardiac punctured, the livers were removed and the length, width, and weight were measured. There was no significant difference on parasitemia between Group 1, 2, 3 and NEG. However, the highest inhibition of parasite s growth was found in Group 3 (61.4%. Observation on hepatomegaly, showed that a significant difference on the length of the liver was found between Group 3 and NEG.