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All Journal ODONTO Dental Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Mutiara Medika: Jurnal Kedokteran dan Kesehatan Dental Journal (Majalah Kedokteran Gigi) The Indonesian Biomedical Journal Padjadjaran Journal of Dentistry Prosiding Seminar Nasional Program Pengabdian Masyarakat Odonto dental journal
Erlina Sih Mahanani, Erlina Sih
Universitas Muhammadiyah Yogyakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Journal : ODONTO Dental Journal

 1 
EFFECT OF FIBROIN SPONGE ON ALVEOLAR BONE REMODELING PROCESS POST TOOTH EXTRACTION Sartika Puspita; Lutfia Siti Hanifatunnisa; Agustin Wulan Suci Dharmayanti; Erlina Sih Mahanani; Edwyn Saleh
ODONTO : Dental Journal Vol 9: Special Issue 1. April 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.0.7-15

Abstract

Background: There are still quite a lot of cases of tooth extraction in Indonesia because of the cavities are not treated or because of other cases. Extraction is the main cause of 90% of bone destruction and a risk of infection and bleeding. Fibroin sponge is a natural polymer material derived from Bombyx mori silk cocoon which contains of 18 amino acids and have a good mechanically, biodegradable and biocompatible. This study aimed to determine the effect of fibroin sponge on the remodeling of post tooth extraction sockets.Method: This study was a laboratory experiment with quasy experimental design using 30 Sprague dawley rats divided into 2 groups. Each group had the mandibular left incisor extracted. The first group as a control was given 15 ug of Curaspon and the second group was given 15 ug of fibroin sponge intra alveolar.Result: The results were observed after the 3rd, 7th, 14th, 21st, 28th days under a light microscope and identified by scoring bone remodeling based on predetermined criteria. Data were analyzed using the Mann-Whitney Test followed by the Kruskall-Wallis Test. The results showed that there was no difference in the process of bone remodeling post tooth extraction in the fibroin sponge group compared to Curaspon (p>0.05).Conclusion: Fibroin sponge has the same effect on the bone remodeling process as Curaspon.
THE CHARACTERISTICS OF SCAFFOLD DESIGN FOR BONE REGENERATION : A LITERATURE REVIEW Erlina Sih Mahanani
ODONTO : Dental Journal Vol 9: Special Issue 1. April 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.0.16-23

Abstract

Background: Scaffold for bone regeneration is called bone graft as well, requires the proper design in order to produce new bone formation. Characteristic requirements are needed. Method: The aimed of this review to discuse the characteristics of scaffold that be needed for bone regeneration. Result: The strength of the scaffold's mechanical structure and degradation profile are adjusted to the time that take for cells to differentiate into bone cells. The swelling ability, porosity size, and interconnected porosity determine the success of incorporation of signal molecules which loaded into the scaffold. The proper selection of molecule signal is needed for stimulating cells to differentiate to be bone cells. The porosity size is adjusted to cell size, because scaffold as a micro enviroment for cells to live, grow and form a new bone. The basic ingredients of scaffold should qualify the biocompatibility standards to be accepted by the body. Scaffold is a micro enviroment for cells to produce bone matrix, and should be degraded properly after the new bone formation is formed. Conclusion: Therefore the right characteristics should be fulfilled in the design of scaffold for bone regeneration.
Co-Authors Agustin Wulan Suci Dharmayanti Ana Medawati, Ana Arya Nur Ihsan Atiek Driana Rahmawati, Atiek Dian Nur’aini Safitri, Dian Dian Nur’aini Safitri Dinda Triani Ahyati Dyah Triswari Dyah Triswari, Dyah Edwyn Saleh Erry Mochamad Arief Erry Mochamad Arief, Erry Mochamad Ferry Sandra Fitranto Arjadi Hana Aulia Hapsari Hastoro Pintadi Idha Ardianingtiyas Idha Ardianingtiyas, Idha Ike Primalia AP Ike Primalia AP, Ike Ikhsan Nur Arifin Khusnatunnisa, Khusnatunnisa Likky Tiara Alphianti Lutfia Siti Hanifatunnisa Mohd Fadhli Khamis Muhammad Aminullah Majedi Muhammad Aminullah Majedi, Muhammad Muhammad Boma Wikan Bhagaskoro Muhammad Romzi Nabil Agustan Mutmainnah, Mutiah Nurul Husna Wulansari Nurul Husna Wulansari, Nurul Pratiwi Nur Widyaningsih Samantha Victoria Samuel Samantha Victoria Samuel, Samantha Victoria Sartika Puspita Siti Nabilah Mat Rippin Widyapramana Dwi Atmaja Wika Putri Adriani Wika Putri Adriani, Wika Yusrina Lukitasari Zainul Ahmad Rajion