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Suharsih
Universitas Nahdlatul Ulama Sumatera Utara
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PERBANDINGAN UJI DIAGNOSTIK GENEXPERT MTB/RIF DENGAN KULTUR SENSITIVITAS ANTIBIOTIK DALAM MENDETEKSI RESISTENSI RIFAMPICIN Mycobacterium tuberculosis PADA PASIEN TB PARU DI RSUP H. ADAM MALIK MEDAN Nurbaity Situmorang; Perry Boy Chandra Siahaan; Suharsih; Dewi Novina Sukapiring
Jurnal Biogenerasi Vol. 7 No. 2 (2022): Jurnal Biogenerasi Vol 7 Nomor 2 tahun 2022
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v7i2.1912

Abstract

WHO recommends GeneXpert Mycobacterium tuberculosis; Rifampicin as an initial examination for the diagnose of drug-resistant tuberculosis and drug-sensitive tuberculosis in pulmonary TB patients. The GeneXpert MTB/RIF examination is a molecular examination method with Nucleic Acid Amplification Technology (NAAT) which can diagnose TB and resistance to Rifampicin within 2 hours. The aims of this study is to determine the comparison of GeneXpert MTB/Rif Diagnostic Test with Drug Sensitivity Culture in Detecting Rifampicin M. tuberculosis resistance in TB patients at H. Adam Malik Hospital, Medan. The sample in this study was the entire population of suspected pulmonary TB at H. Adam Malik Hospital Medan who had MTB examination results. Post; rif. res. The sample size was using total sampling, namely the sampling technique where the number of samples was the same as the population, namely 128 patients in 2020. The results of the Rifampicin TCM Antibiotic Test were found that 128 people had Rifampicin Resistant results. Based on the percentage of the results of the MGIT Antibiotic Sensitivity Test, 125 people were found to have Rifampicin Resistant results and 3 people had Rifampicin Sensitive results. Based on the results, it can be seen that the sensitivity value of the TCM tool to DST MGIT culture is 97.7%. The Conclusions of these Research is the ability of the GeneXpert MTB/Rif method to detect rifampin resistance can be used as a screening tool to diagnose rifampin-resistant TB.
EFEKTIVITAS PEMBERIAN JUS BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP KADAR HEMOGLOBIN TENAGA MEDIS DI RUMAH SAKIT AMALIA MEDIKA PANGKALAN KERINCI Nurbaity Situmorang; Suharsih; Yuni Darmawati Saragih
Jurnal Biogenerasi Vol. 8 No. 2 (2023): Artikel Publish Agustus 2023
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v8i2.2802

Abstract

Anemia is a common problem that often occurs in developing countries including Indonesia, most anemia is caused by hemoglobin levels less than 11 g/dl. Hemoglobin is a complex protein that binds iron (Fe) and is present in erythrocytes. Low hemoglobin levels are caused by iron deficiency, folic acid deficiency and chronic disease. The increase in hemoglobin levels with iron and vitamin C can be higher than with iron alone. Red dragon fruit (Hylocereus polyrhizus) has long been consumed by the public as a medicine to increase blood. This fruit contains organic acids, protein, minerals such as potassium, magnesium, calcium and iron as well as vitamin C. This study aims to determine the effectivity of giving red dragon fruit juice (Hylocereus polyrhizus) on hemoglobin levels in medical personnel at Amalia Medika Hospital Pangkalan Kerinci. This study used a pre-experimental method with a one group pretest-posttest design, in which hemoglobin levels were measured before giving red dragon fruit juice and after the respondent was given red dragon fruit juice 4 times in 30 days. The results showed that there was a significant difference between hemoglobin levels before and after administration of red dragon fruit juice with p=0.000 (α=0.05) in the paired sample t test. This means that there is an effect of giving dragon fruit juice on the hemoglobin level of medical staff at Amalia Medika Hospital in Pangkalan Kerinci, namely an increase in hemoglobin levels after being given dragon fruit juice of 2.61 g/dL to the respondent.
Co-Authors Dewi Novina Sukapiring Nurbaity Situmorang Perry Boy Chandra Siahaan Yuni Darmawati Saragih