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All Journal Jurnal Pembelajaran dan Biologi Nukleus Journal of Natural Sciences
Hermawan Purba
Sekolah Tinggi Ilmu Kesehatan (STIKes) Senior Medan
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media

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Journal : Journal of Natural Sciences

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Uji Aktivitas Antijamur Ekstrak Etanol Herba Patikan Kebo (Euphorbia hirta L.) Terhadap Candida albicans Helen Anjelina Simanjuntak; Hermawan Purba; Wan Yuli Anjani; Rahmiati Rahmiati; Toberni S Situmorang
Journal of Natural Sciences Vol 3, No 3 (2022): Journal of Natural Sciences November
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v3i3.303

Abstract

The patikan kebo plant is used to cure respiratory infections, malaria, liver, hypertension, gastrointestinal, skin diseases, accelerate wound healing, antidotes, hepatitis, rheumatism and tumors. The purpose of this study was to determine the antifungal activity of patikan kebo. The research method was carried out experimentally with the paper disc diffusion method. The antifungal activity test of each concentration (1%, 2%, 3%, 4%, ketoconazole, DMSO) had respective values (7.14 mm, 7.67 mm, 8.51 mm, 8.80 mm, 26.81 mm, 0 mm). The content of secondary metabolites in the patikan kebo plant are saponins, tannins, alkaloids, steroids/triterpenoids and flavonoids. The patikan kebo plant has medium category antifungal potential.
Potensi Buah Andaliman (Zanthoxylum acanthopodium DC.) sebagai Antibakteri Terhadap Salmonella typhi Helen Anjelina Simanjuntak; Hermawan Purba; Cander Pasaribu; Junius Gian Ginting; Rahmiati Rahmiati; Toberni S Situmorang
Journal of Natural Sciences Vol 4, No 2 (2023): Journal of Natural Sciences Juli
Publisher : Mahesa Research Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34007/jonas.v4i2.404

Abstract

Typhoid fever is a major disease of death in the medical field caused by Salmonella typhi infection with symptoms including fever, mucosal lesions, vomiting, diarrhea, fluid loss, septicemia, and peritonitis. The use of natural plants to cure infectious diseases such as andaliman fruit. The aim of this study was to determine the antibacterial activity of Andaliman fruit extract on the growth of Salmonella typhi. Experimental research method. The Kirby-bauer method was used for the antibacterial test, the maceration method was used for extraction. The results of phytochemical compounds found flavonoids, tanins, saponins, tannins, alkaloids steroids, and triterpenoids in simplicia and andaliman fruit extracts. All extracts have the potential to inhibit the growth of Salmonella typhi, with the diameter of the inhibition zone consisting of 10.04 mm, 12.22 mm, 15.46 mm and 16.68 mm in the strong category. These doses are 10%, 30%, 50%, and 70%. The analysis shows the potential of Andaliman fruit extract as an antibiotic in the treatment of typhoid fever.
Co-Authors Cander Pasaribu Defcato Firmawati Zega Fani Nuryana Manihuruk Helen Anjelina Simanjuntak Junius Gian Ginting Lydia Br Barus Lydia Br. Barus Mesi Puspita Sari Mestika Clemesiya Yulianti Daeli Rahmiati Rahmiati Singarimbun, Nurbaiti Br Toberni S Situmorang Toberni S Situmorang Wan Yuli Anjani