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All Journal Jurnal Kedokteran The Indonesian Biomedical Journal Jurnal Sains Teknologi dan Lingkungan (JSTL) Jurnal Biologi Tropis
Philip Habib
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Jurnal Biologi Tropis

 1 
Cholangiocarcinoma: Risk Factors, Diagnostic Tools, and Current Treatment Options Adli Putra Nugraha; Baiq Ghassani Kayla; Febbi Anggy; Ni Made Utami Wulandari; Wina Arsylia Fakar; Philip Habib
Jurnal Biologi Tropis Vol. 23 No. 4 (2023): October - December
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i4.5741

Abstract

Cholangiocarcinoma is a disease caused by the differentiation of cells in the bile epithelium or liver parenchyma into malignant cells called cholangiocytes. This literature review presents the current risk factors, diagnostic tools, and treatment choices of cholangiocarcinoma. Publication about the current risk factors, diagnostic tools, and treatment choices of cholangiocarcinoma were collected from the Pubmed database until August 25, 2022. The keywords of the research were “cholangiocarcinoma”, “risk factor”, “diagnostic”, and “treatment”. Cholangiocarcinoma has many risk factors, from choledochal cysts, and primary sclerosing cholangitis, to asbestos exposure. The diagnosis of cholangiocarcinoma is difficult and requires the combined interpretation of different diagnostic modalities. Examinations that can be done for the diagnosis and staging of cholangiocarcinoma are MRI and CT. However, if the diagnosis remains uncertain, endoscopic examination and tissue sampling may be performed. After the diagnosis, there are several treatments, namely surgical therapy (surgical excision of bile duct tumors), endoscopic therapy (endoscopic biliary dilatation), radiological therapy (percutaneous transhepatic palliative biliary dilatation), chemotherapy and radiotherapy, and photodynamic therapy. Cholangiocarcinoma is a malignancy of cells in the biliary epithelium or liver parenchyma (cholangiocytes) that has many risk factors. The diagnosis of cholangiocarcinoma is difficult and requires a combined interpretation of the different diagnostic modalities, including MRI, CT, endoscopy, and tissue sampling. After the diagnosis, there are several treatments, namely surgical therapy, endoscopy, radiology therapy, chemotherapy and radiotherapy, and photodynamic therapy.
Gallbladder Empyema: A Dreadly Complication of Acute Cholecystitis Dinda Puspita Sari; Elvienna Shaffiranisa; Amrullah Muliawan Hamdin; Clara Nadila; Philip Habib
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.5783

Abstract

Gallbladder empyema is a severe form of acute cholecystitis with additional suppuration with an incidence rate of 6.3%-26.6% and a mortality rate 3%. If not treated promptly, gallbladder empyema can cause complications. Therefore, in this literature review we will discuss gallbladder empyema in more depth and the immediate treatment that must be carried out to avoid complications in patients. In this literature review Schoolar, we conducted a search on the PubMed and Sciencedirect database    using    the search keyword “gallbladder empyema”, “empyema”, and “gallbladder”. Gallbladder empyema can occur due to bile that cannot be excreted from the gallbladder will cause infection from microorganisms so that the gallbladder becomes full of exudative material in the form of pus, causing acute inflammation. Diagnosis of gallbladder empyema can be done using Ultrasonography and Computed Tomography Scan (CT Scan). Percutaneous transhepatic gallbladder drainage (PTGBD) is a procedure for the initial management of gallbladder empyema before laparoscopic cholecystectomy. If gallbladder empyema is treated immediately, the prognosis is good. If not treated promptly, gallbladder empyema can lead to peritonitis, and bacteremia leading to a rapid systemic inflammatory response, shock, and sepsis.
Co-Authors Adli Putra Nugraha Adnanto Wiweko Ahmad Taufik S Amrullah Muliawan Hamdin Baiq Ghassani Kayla Clara Nadila Didit Yudhanto Dinda Puspita Sari Elvienna Shaffiranisa Fathul Djannah Fathul Djannah Febbi Anggy Hamsu Kadriyan Lalu Hamri Fikri Mohammad Rizki Mulyanto Mulyanto Ni Made Utami Wulandari Nimas Resti Nurhidayati Siddik Triana Diah Cahyawati Wina Arsylia Fakar