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All Journal PHARMACON Pharmascience Hydrogen: Jurnal Kependidikan Kimia Room of Civil Society Development
Hasnaeni hasnaeni, Hasnaeni
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Arts Humanities Chemistry Education Medicine & Pharmacology Social Sciences Other

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KAJIAN EFEK ANTI RADANG KAYU BETA-BETA (Lunasia amara Blanco.) hasnaeni, Hasnaeni
PHARMACON Vol 5, No 2 (2016): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.5.2016.12164

Abstract

KAJIAN EFEK ANTI RADANG KAYU BETA-BETA (Lunasia amara Blanco.) Hasnaeni1,2), Sudarsono3), Arief Nurrochmad4), Sitarina Widyarini5) 1) Faculty of Pharmacy, Muslim Indonesia University, Makassar, South  Sulawesi, Indonesia 2)Doctorate Programme of Faculty of Pharmacy, Universitas Gadjah Mada. 3)Department of Biologycal Pharmacy, Faculty of Pharmacy, Gadjah Mada      University 4)Department of Pharmacology,  Faculty of Pharmacy, Gadjah Mada University 5)Department of Pathology Anatomy, Faculty of Veterinary Medicine,   Gadjah Mada University Email : hasnaeniyahya@yahoo.co.id ABSTRACT Beta-beta wood (Lunasia amara) is one of the traditional medicinal plants that has potential as an anti-inflammatory. This plant has been used as medicine by the people for the treatment of leg swelling, skin diseases and inflammation or irritation of the eyes. Inflammation measurements using calipers. Animals were divided into 6 groups. Statistical analysis showed no significant difference between the percentage anti-inflammatory  a group beta-beta wood extract and positive control group. The results showed that beta-beta wood can be developed as an anti-inflammatory drug. Keywords: Anti-inflammatory, Beta-beta wood (Lunasia amara) ABSTRAK Kayu beta-beta (Lunasia amara) merupakan salah satu tanaman obat tradisional yang mempunyai potensi sebagai antiinflamasi. Tanaman ini telah digunakan sebagai obat  oleh masyarakat untuk pengobatan kaki bengkak, penyakit kulit dan radang atau iritasi mata. Pada penelitian ini telah dilakukan kajian efek anti radang kayu beta-beta dengan menggunakan jangka sorong sebagai alat pengukuran radang yang terjadi setelah dilakukan induksi terhadap hewan coba dalam hal ini mencit Balb/C. Hewan coba dibagi menjadi 6 kelompok dengan menggunakan Natrium diklofenak sebagai kontrol positif anti radang. Hasil analisis statistik memperlihatkan ada perbedaan rata-rata persentase daya antiinflamasi antara kelompok senyawa uji dan kelompok kontrol positif. Hal ini menunjukkan bahwa senyawa uji ekstrak etanol kayu beta-beta (Lunasia amara) mempunyai  efek anti radang berdasarkan pengukuran kemampuan senyawa dari tanaman untuk menurunkan bengkak melalui pengukuran tebal kaki  yang dibandingkan dengan kelompok kontrol positif Natrium diklofenak. Hasil penelitian ini membuka harapan baru untuk dapat dilakukan pengujian lebih lanjut terhadap efek anti radang  kayu beta-beta. Kata Kunci : Anti radang, kayu beta-beta (Lunasia amara)    
Health Education about Preparation of Exclusive Breastfeeding for Pregnant Women Firawati, Firawati; Hasnaeni, Hasnaeni; Kasim, Jamila; A, Alfiah; Kadrianti, Erna
Room of Civil Society Development Vol. 2 No. 6 (2023): Room of Civil Society Development
Publisher : Lembaga Riset dan Inovasi Masyarakat Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59110/rcsd.243

Abstract

Mother's Milk is the ideal food for the growth and development of babies. in Indonesia the coverage of exclusive breastfeeding is still far from the national target of 80%, health education activities for pregnant women related to knowledge about exclusive breastfeeding, the benefits of breastfeeding for babies and mothers, nutritional and psychological preparation and practicing proper breastfeeding being solution The right way to prepare yourself from the start so that pregnant women can provide exclusive breastfeeding, his community service is carried out at the Bara-Baraya Community Health Center, Makassar City. The service method is interactive participation accompanied by lectures, questions and answers, discussions, and roleplay. As a result of this service, we get enthusiastic pregnant mothers who actively ask questions, so they are committed to providing exclusive breast milk to their babies, thus this health education is an effective effort to increase knowledge among pregnant women. It is recommended that health workers can carry out health education on an ongoing basis considering that there are still pregnant women who have insufficient knowledge about the importance of preparing for exclusive breastfeeding.
Uji Aktivitas Antioksidan Ekstrak Etanol Sabut Buah Pinang (Areca catechu L.) Pratiwi, Indah; Hasnaeni, Hasnaeni; Handayani, Selpida
Jurnal Pharmascience Vol 11, No 1 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i1.16811

Abstract

Penelitian ekstrak etanol buah pinang (Areca catechu L.) telah dilakukan. Penelitian ini untuk mengetahui nilai IC50 antioksidan optimal buah pinang (A. catechu L.) menggunakan metode DPPH. Sampel buah pinang (A. catechu L.) diekstraksi dengan etanol 96% menggunakan metode ekstraksi maserasi. Ekstrak diuapkan untuk mendapatkan ekstrak etanol kental menggunakan rotary evaporator. Skrining fitokimia dilakukan untuk mengetahui kandungan metabolit sekunder. Hasil skrining menunjukkan adanya senyawa flavonoid dan alkaloid dalam ekstrak etanol buah pinang. Pengujian aktivitas antioksidan dilakukan dengan menggunakan DPPH dan menggunakan quercetin sebagai senyawa standar. Nilai IC50 ekstrak etanol diketahui sebesar 69,979 µg/mL. Hasil penelitian menunjukkan adanya potensi ekstrak etanol buah pinang sebagai antioksidan kuat. Kata Kunci: 2,2-Diphenyl-1-Picrylhydrazyl (DPPH), Flavanoid, Nilai IC50, Maserasi, Kuersetin The purpose of this study was to determine the optimal antioxidant IC50 value of Areca catechu L. using the DPPH method. Areca fruit extract (Areca catechu L.) with 96% ethanol using maceration procedure. The extract was evaporated using a rotary evaporator to obtain concentrated ethanol extract, after which a phytochemical screening was carried out to determine the content of secondary metabolites. Screening results showed that flavonoids and alkaloids were found in the ethanol extract of areca nut coconut shells. In addition, antioxidant activity was also tested with DPPH and uses quercetin as a standard. The IC50 of 96% ethanol extract is 69,979 µg/mL. In this review, IC50 results were obtained which showed the potential of A.catechu  ethanol extract as a strong antioxidant
Cytotoxic Activity of Gude Leaves (Cajanus cajan) using The Brine Shrimp Lethality Test (BSLT) Method Emelda, Andi; Hasnaeni, Hasnaeni; Ulfa, Amanda
Hydrogen: Jurnal Kependidikan Kimia Vol 12, No 2 (2024): April-May 2024
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v12i2.11077

Abstract

Gude Leaves (Cajanus cajan) are a traditional medicinal plant for treating diarrhea. The ingredients contained in Gude leaves are flavonoids, such as kajanol, quarcetin and luteolin and also contain other secondary metabolites, tannins, saponins, alkaloids, terpenoids and phenols. Scientifically, Gude leaves have antimalarial, antidiabetic, anthelmintic, antioxidant, antibacterial and anticancer activity. This research aims to determine the toxicity of gude leaves (C. cajan) using the Brine Shrimp Lethality Test (BSLT) method. This research began by carrying out two extraction methods, namely maceration and UAE (Ultrasonic Assisted Extraction) on samples of gude leaves using 70% ethanol solvent. Then a phytochemical screening was carried out which showed that samples of gude leaves contained alkaloids, flavonoids, steroids, saponins and tannins. Experimentation the toxicity of gude leaf extract using maceration and UAE methods on Artemia Salina Leach larvae, each divided into 5 test groups, namely 4 treatment groups (concentrations of (250 ppm,  LC=23,33% & 33,33%) ; (500 ppm, LC= 56,67% & 60%); (750 ppm, LC= 70% & 73%); and (1000 ppm, LC= 80%) and 1 positive control group (sea water ). The research results can be seen through probit analysis by calculating the LC50 value. The LC50 value of gude leaf extract using the maceration method was 242.52 and the result of gude leaf extract using the UAE method was 394.16 (Toxic).  This research provides information regarding the toxic effects of gude leaf extract.
Identification of Medicinal Chemicals (BKO) Piroxicam in Jamu Pegal Linu Preparations in Makassar City Hasnaeni, Hasnaeni; Handayani, Selpida; Andina, Velda
Hydrogen: Jurnal Kependidikan Kimia Vol 12, No 1 (2024): February 2024
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v12i1.10576

Abstract

The aim of the research was to identify Piroxicam in herbal medicine for rheumatic pain circulating in Makassar. There are several traditional medicines that contain medicinal chemicals. Research has been conducted on the identification of medicinal chemicals (BKO) on several rheumatic herbs preparations in herbs shops in Makassar. The BKO which is often included in rheumatic herbs is the NSAID group, one of which is piroxicam. This inspection was conducted to know the presence of the chemical drug piroxicam contained within rheumatic herbs preparations and the samples used were 5 samples. The method used was a qualitative test using thin layer chromatography (TLC) consisting of a mobile phase mixed with n-hexane and acetone (7:3) and a stationary phase using Silica Gel GF254. The results of the TLC examination from 5 samples of herbal medicine added BKO piroxicam contained 3 samples including herbs A, B, and C because they had the same stain color at the same Rf value as the piroxicam. Some of the rheumatic herbs circulating in Makassar contain medicinal chemicals in the form of piroxicam.
Co-Authors A, Alfiah Andi Emelda Andina, Velda Erna Kadrianti Firawati Firawati Indah Pratiwi Kasim, Jamila Selpida Handayani, Selpida Ulfa, Amanda