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All Journal Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Jurnal Pengabdian Teratai
Fatimah Mappanyompa
Universitas Muhammadiyah Makassar
Agriculture, Biological Sciences & Forestry Computer Science & IT Economics, Econometrics & Finance Languange, Linguistic, Communication & Media Social Sciences Veterinary Other

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The Effect of Ajwa Date Fruit Extract (Phoenix Dactylifera L.) Against Liver Damage in White Rats (Rattus Norvegicus) Induced by Meloxicam Fatimah Mappanyompa; M Aryadi Arsyad; Dwi Kesuma Sari; Sartini Natsir; Muhammad Husni Cangara; Yulia Yusrini Djabir
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 7, No 1, JANUARY 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v7i1.21788

Abstract

Abstract Objective: This study was aimed to investigate the protective effect of Ajwa date palm extract (Phoenix Dactylifera L.) against liver damage in white rats (Rattus norvegicus) induced by Meloxicam. Methods: The samples used in this study were twenty five male white rats divided into five groups with body weight 200 – 300gr, namely a healthy control group, negative control given Meloxicam 30mg/kgBB, treatment group 1 was given Ajwa date fruit extract 75mg/kgBW and Meloxicam 30mg/kgBW, treatment group 2 was given Ajwa date fruit extract 150mg/kgBW and Meloxicam 30mg/kgBW, and treatment group 3 was given Ajwa date fruit extract 300mg/kgBW and Meloxicam 30mg/BW for 14 days. On the 15th day, the rats were anesthetized for blood tests and euthanized for liver organ observation. Results: The result showed by giving Ajwa date palm extract with higher doses and Meloxicam 30mg/kgBW, resulted a decrease in ALT and AST enzyme levels which were close to normal values ​​in rats. Histological observation showed extensive damage to liver cell tissue, with signs of inflammation, hemorrhage, necrosis, and hydropic degeneration. By giving high doses of Ajwa date palm extract and Meloxicam 30mg/kgBW, gave a view of a decrease degree on liver tissue damage. Conclusion: The extract of Ajwa date palm (Phoenix Dactylifera L.) can provide a protective effect against liver damage in white rats (Rattus Norvegicus) induced by Meloxicam with decreased levels of liver function enzymes which are Alananine Transaminase (ALT) and Aspartate Aminotransferase (AST), along in the changes of liver histopathological view which showed a decrease degree of liver cell tissue damage. Keywords: Ajwa date palm extract; Meloxicam; Liver tissue damage.
PEMERIKSAAN KESEHATAN DAN PROFIL METABOLIK PADA CIVITAS AKADEMIKA Ami Febriza; Nurmila Nurmila; Nelly Nelly; Fatimah Mappanyompa
Jurnal Pengabdian Teratai Vol 4 No 1 (2023): Jurnal Pengabdian Teratai
Publisher : Lembaga Penelitian Dan Pengabdian Pada Masyarakat (LPPM) Institut Bisnis dan Informatika (IBI) Kosgoro 1957

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55122/teratai.v4i1.770

Abstract

Gaya hidup saat ini membuat masyarakat semakin malas melakukan kegiatan fisik, selalu ingin hal yang instan, hal itu menghabiskan waktu dengan alat komunikasi gadget mereka, meningkatkan kebiasaan mengonsumsi makanan kurang sehat, dan life style yang tidak diimbangi dengan olahraga teratur. Seseorang yang tergolong memiliki kelebihan berat badan (overweight) biasanya cenderung lebih rentan terkena penyakit jantung koroner, diabetes, osteoatritis dan penyakit degeneratif lainnya. Kondisi meningkatkan kejadian inaktivitas fisik pada masyarakat yang berujung pada meningkatnya perilaku sedentary lifestyle. Tujuan: kegiatan pengabdian masyarakat ini bertujuan untuk mengukur tingkat profil kardiometabolik pada civitas akademika Unismuh melalui pemeriksaan kesehatan. Metode: Pemeriksaan kesehatan dengan melalui 3 tahapan, yaitu persiapan, pelaksanaan dan evaluasi kegiatan. Hasil: Ditemukan profil metabolis pada sebagian besar responden dalam batas normal, meskipun beberapa tergolong obesitas. Kesimpulan: Pemeriksaan kesehatan dan skrining profil metabolik pada civitas akademika dapat meningkatkan kesadaran terkait penyakit metabolik dan degeneratif bagi para dosen dan tenaga kependidikan di Fakultas Kedokteran Universitas Muhammadiyah Makassar.
Co-Authors Ami Febriza Arsyad, Muhammad Aryadi Cangara, Husni Dwi Kesuma Sari Nelly Nelly Nurmila Nurmila Sartini Natsir Yulia Yusrini Djabir