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PENYULUHAN KADAR CRP (C-REACTIVE PROTEIN) PADA PENDERITA TUBERKULOSIS DI KECAMATAN CILAWU SEBAGAI PENANDA ADANYA INFLAMASI Astari Nurisani; Mamay Mamay; Gina Nafsa Mutmaina; Sugiah Sugiah; Wisnu Arya Pratama
Ekalaya: Jurnal Pengabdian Kepada Masyarakat Indonesia Vol. 2 No. 2 (2023): Ekalaya Journal
Publisher : Nindikayla Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57254/eka.v2i2.57

Abstract

Infection due to tuberculosis bacteria will cause inflammation in the body which will stimulate the emergence of C-Reactive Protein as a biomarker of inflammation. C-Reactive Protein (CRP) is a polypeptide molecule of the pentraxin group which is produced in the liver and controlled by cytokines especially Interleukin-6 (IL-6). CRP is useful for monitoring disease progression. CRP concentration is related to disease severity, infection and treatment effect. The purpose of this community service is to see CRP (C-Reactive Protein) levels in tuberculosis sufferers in the Cilawu sub-district and provide an understanding of CRP examination. The method used is counseling with LCD and examination of CRP levels in tuberculosis patients. The sufferers are collected in a house that has been mutually agreed upon. The results of the activity were that most of those present had CRP examination results on the 30 samples that had been examined, 24 people (80%) had positive results, and 6 people (20%) had negative results. CRP levels in positive tuberculosis patients obtained various results between 6 mg/L to 192 mg/L. Conclusion: the results of this community service illustrate that there is an inflammatory response of CRP to tuberculosis bacterial infection. After carrying out counseling and examining CRP levels, the community, especially tuberculosis sufferers, became aware and interested in carrying out CRP examinations as a form of monitoring the level of infection they were suffering from
Pemeriksaan C-Reactive Protein (CRP) Kualitatif dan Semi Kuantitatif pada Penderita Tuberkulosis Astari Nurisani; Mamay Mamay; Meti Rizki Utari; Zahara Farhan; Wisnu Arya Pratama
Jurnal Kesehatan Vol. 10 No. 2 (2022): Oktober: Health Journal "Love That Renews"
Publisher : Sekolah Tinggi Ilmu Kesehatan Santo Borromeus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55912/jks.v10i2.99

Abstract

Infeksi akibat bakteri tuberkulosis akan mengakibatkan peradangan didalam tubuh yang akan merangsang munculnya C-Reactive Protein sebagai biomarker peradangan. C-Reactive Protein (CRP) merupakan molekul polipeptida kelompok pentraxin yang diproduksi di hati dan dikontrol oleh sitokin khususnya Interleukin-6 (IL-6). CRP bermanfaat untuk memonitor perkembangan penyakit. Konsentrasi CRP berhubungan dengan tingkat keparahan penyakit,infeksi dan efek pengobatan. Tujuan penelitian ini adalah untuk melihat gambaran kadar CRP (C-Reactive Protein) pada penderita tuberkulosis di RSUD Dr. Slamet Garut. Pemeriksaan CRP dilakukan secara kualitatif dan semi kuantitatif. Hasil pemeriksaan CRP pada 30 sampel yang telah diperiksa didapat hasil positif sebanyak 24 orang (80%), dan negatif sebanyak 6 orang (20%). Berdasarkan hasil pemeriksaan diperoleh kadar CRP pada pasien tuberkulosis positif didapat hasil beragam antara 6 mg/L sampai 192 mg/L. Hasil penelitian ini menggambarkan adanya respon inflamsi CRP terhadap infeksi bakteri tuberkulosis. Saran dalam penelitian ini adalah data penelitian ini digunakan sebagai data acuan penelitian selanjutnya dalam pemeriksaan CRP metode kuantitatif mengenai gambaran kadar CRP sebelum dan sesudah pengobatan..
Co-Authors Astari Nurisani Gina Nafsa Mutmaina Mamay Meti Rizki Utari Sugiah Sugiah Zahara Farhan