Dhega Anindita Wibowo, Dhega Anindita
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THE INFLUENCE OF CHEESE CONSUMPTION ON THE DEGREE OF ACNE VULGARIS IN STUDENTS OF MEDICINE FACULTY OF DIPONEGORO UNIVERSITY Koncara, Fatan Khalif; Wibowo, Dhega Anindita; Riyanto, Puguh; Wikanta, Edmond Rukmana
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 2 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.253 KB) | DOI: 10.14710/dmj.v9i2.27076

Abstract

Introduction : Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles with a polymorphic clinical picture consisting of various skin disorders in the form of blackheads, papules, pustules, nodules, and scar tissue. Four pathogenesis underlying the emergence of AV include polysebaseal follicle hyperproliferation, excess sebum production, inflammation, and the presence of Propionibacterium acnes. The cause of this multifactorial AV, one of which is a factor of consuming fatty foods, especially saturated fat, one of the foods is cheese. Cheese is one of the foods that we usually consume as processed foods that contain lots of saturated fat. Consuming fatty foods on an irregular basis can cause acne vulgaris. Objectives : To determine the relationship of fatty food consumption with the severity of acne vulgaris in Diponegoro University Kedokeran Faculty studentsMethods : This study uses a descriptive observational design with cross sectional design in which the researcher will describe how the incidence of acne vulgaris, the severity of acne vulgaris and the factors that influence acne vulgaris, especially regarding saturated fat consumption in excess cheese in Diponegoro University Medical School students. Samples were taken by purposive sampling to produce 40 students who met the inclusion and exclusion criteria. Assessment is assessed by filling out questionnaires suffering from acne vulgaris and assessing acne vulgaris in respondents. Analysis of the data used in the study is an analysis with the Chi Square test. Result : In conclusion, clustered pimples are a dominant factor in the assessment of acne (p<0,05). Conclusion: In this study it was found that there was no significant relationship between cheese consumption with the severity of acne vulgaris and pimples arising from acne is acne that occurred before the existence of this studyKeywords : acne vulgaris, fat, cheese
The Effect of Coffee on Spermatozoa Motility and Morphology of BALB/c Mice Exposed to Electric Mosquito Repellent Mulyono, Yehezkiel Andrew; Prihasna, Septika Nuri; Wibowo, Dhega Anindita; Johan, Andrew; Ngestiningsih, Dwi; Juniarto, Achmad Zulfa
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 12, No 1 (2021): January - June 2021
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (946.485 KB) | DOI: 10.30659/sainsmed.v12i1.12580

Abstract

Introduction: Electric mosquito repellent which contains d-allethrin producing free radicals, affects the quality of sperm motility and morphology. Antioxidants contained in coffee can counteract the free radicals in the body. Objective: To evaluate the effect of coffee on sperm motility and morphology of BALB/c mice exposed to electric mosquito repellent. Methods: In this experimental study was conducted with post-test only control group design, 24 BALB/c mice randomized into 4 groups. The negative control group was a group without treatment. The positive control group was exposed to electric mosquito repellent. Group P1 and P2 were exposed to electric mosquito and given the coffee solutions with the doses respectively 52 mg/0.5 mL and 78 mg/0.5 mL. The treatment was given for 35 days. On the 36th day, all mice were terminated and their sperm motility and morphology were examined. The data were then analyzed with the non-parametric test of Kruskal-Wallis. Differences were considered significant when the value of p<0.05 with confidence interval 95%.Results: The result of pairwise comparison test progressive sperm motility shows that there was a significant difference between positive control group with P2 group (p=0.006), positive control group with negative control group (p<0.001), and P1 group with negative control group (p=0.004). The result of Kruskal-Wallis test for sperm morphology shows that there was no significant difference between those four groups (p=0.885).Conclusion: Coffee can significantly increase the sperm motility but didn’t significantly increase the normal sperm morphology percentage of BALB/c mice exposed by electric mosquito repellent.