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All Journal Dentika Dental Journal Padjadjaran Journal of Dentistry

Sri Tjahajawati, Sri

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Author-ID : 631627

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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SALIVA AS A POTENTIAL DIAGNOSTIC OF BIOMARKER OF ORAL AND SYSTEMIC DISEASES: SALIVA SEBAGAI BIOMARKER POTENSIAL DIAGNOSTIK PENYAKIT RONGGA MULUT DAN SISTEMIK Lesmana, Dian; Tjahajawati, Sri; Lubis, Vita Tarawan
Dentika: Dental Journal Vol. 19 No. 2 (2016): Dentika Dental Journal
Publisher : TALENTA

Saliva is a biological fluid that is secreted by the major, minor and other accessories salivary glands. Saliva has a high potential as an indicator that reflects the health of our body. Saliva also plays an important role as a protector, lubricate oral structure with mucin, set a neutral pH through the buffer capacity, clean the oral cavity, stimulate wound healing, help the taste buds in the taste of food, facilitate the process of chewing food, form a bolus and make it easier swallowing, and minimize food particles through the activity of the enzyme amylase and lipase. The use of saliva as a biomarker in diagnosing provide more advantages than the serum and other body fluids due to using non-invasive techniques, cost-efficient, as well as methods for collecting samples for disease screening without the need to train professional personnel. The benefits derived from the saliva as a biomarker are early detection and screening of disease to the development of caries, periodontal disease, tumors and malignancy, hereditary, wound healing, autoimmune disease, infectious diseases, cardiovascular diseases, drug monitoring, forensic, and the psychological influence. At this time, the function of saliva as a diagnostic biomarker is not widely known, therefore the development of salivary further enhance because it can produce functional similarities with serum and reflect the body's physiological status in the oral cavity and systemic disease.

Pigmentation Lesions and Salivary Flow Rates on Woman Smokers: Lesi Pigmentasi dan Laju Aliran Saliva pada Wanita Perokok Fatimah, Aulia; Tjahajawati, Sri; Razali, Ervin
Dentika: Dental Journal Vol. 22 No. 2 (2019): Dentika Dental Journal
Publisher : TALENTA

Smoking habit has many negative effects towardswomenâ€™s systemic and oral health. One of them are decrease of salivary flow rate and an appearance of pigmentation lesion in gingiva. The aim of this research is to obtain data regarding salivary flow rate and pigmentation lession on women smokers.This descriptive research used 50 samples by simple random sampling method. The salivary flow rate data was obtained by spitting method and the pigmentation lesion data was described by visual method. The other data wasobtained through filling the questionnaire. By the findings of this research, it was found that the mean value of salivary flow rate and pigmentation lession of women smokerswho consumed1-8 cigarettes per day for 1-2, 2-5 and > 5 years were 0.4 ml/min & 51,7%, 0.4 ml/min & 100%, 0.4 ml/min & 100%. The mean value of salivary flow rate and pigmentation lession of women smokerswho consumed9-16 cigarettesper day for 1-2, 2-5 and > 5 years were 0.4 ml/min & 100%, 0.4 ml/min & 100%, 0.4 ml/min & 90%. The mean value of salivary flow rate and pigmentation lession of women smokerswho consumed>16 cigarettes per day for 1-2, 2-5 and > 5 years were 0.3 ml/min & 100%, 0.2 ml/min & 100%, 0.2 ml/min & 100%. The conclusion shows that salivary flow rate on women smokers has a lower value compared to normal salivary flow rate or its called oligosialia and most of the subjects have

Co-Authors Dewi ANGGRAENI Fatimah, Aulia Lesmana, Dian Lubis, Vita Tarawan Marry Siti Mariam Razali, Ervin Ririn Ariyanti, Ririn Rosiliwati Wihardja, Rosiliwati Silvi Kintawati Soo Ling Fu, Soo Ling

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