Article Per Year (5 Year)
p-Index From 2019 - 2024
0.408
P-Index
This Author published in this journals
All Journal Indonesian Journal of Global Health research Jurnal Pengabdian kepada Masyarakat Nusantara
Dzaki Fikri Firdaus Bakri
Sekolah Tinggi Ilmu Kesehatan Nasional
Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Nursing Public Health Social Sciences

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Formulation and Characterization of Nanoemulsion from Traditional Extracts for Antidiabetic Dzaki Fikri Firdaus Bakri; Muhtadi Muhtadi; Erindyah Retno Wikantyasning
Indonesian Journal of Global Health Research Vol 5 No 3 (2023): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v5i3.2035

Abstract

Diabetes is a degenerative disease with the highest number of sufferers in the world. Traditional medicine naturally uses extracts of plants and animals in great demand. Curse fish or snakehead fish (Channa striata), elephant lempuyang (Zingiber zerumbet L) and rambutan rind (Nephelium lappaceum) are proven to have active ingredients of albumin, quercetin and geraniin as anti-diabetics. Disadvantages of these active compounds, namely having low solubility, permeability and stability, causing a decrease in bioavailability. Self Nano Emulsifying Drug Delivery System (SNEDDS) is a form of nanoemulsion and is a solution for delivering active compounds to increase permeability, stability and solubility of active compounds. The formula was made using olive oil as the oil phase, PEG 400 as the cosurfactant, span 80, tween 20 and tween 80 as the surfactant. The research aims to obtain the optimum nanoemulsion formula using the HLB method. Percent transmittance and emulsification time are used to determine the optimum formula. The selected formula was further tested with a particle size analyzer, zeta potential, PDI. Based on the 30 formulas that were made, F9 was the chosen formula with an HLB value of 15 with the oil, surfactant, cosurfactant phases at a ratio of 8:1:1. Formula F9 has an emulsification time of 18.76 seconds, a transmittance of 97.8%. The particle size test results were 196.2 nm and -30.1 zeta potential values. The research results showed that SNEDDS preparations were able to form nanoemulsions spontaneously and had good characteristics.
Inovasi Teknologi Kristalisasi Serbuk Instan Kombinasi Jahe dan Kencur guna Meningkatkan Pengetahuan dan Ketrampilan di Desa Wirun Retnowati Adiningsih; Iwan Setiawan; DZAKI FIKRI FIRDAUS BAKRI
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 4 No. 4 (2023): Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN)
Publisher : Sistem Informasi dan Teknologi (Sisfokomtek)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cardiovasculer diseases are the main causes of death in the world with 32% of total deaths. Hypertension is one of the main risk factors for cardiovascular disease, so it needs special attention in society. Ginger (Zingiber officinale Rosc) and galangal (Kaempferia galanga) are medicinal plants and easy to found at home, so it can the best solutions for long term treatment of hypertension. Community service activities were carried out for the Kelompok Wanita Tani (KWT) in Wirun, Mojolaban, Sukoharjo. This research includes analysis of public knowledge regarding hypertension, education on the benefits of product as antihypertensives, education on making crystal powder from ginger and galangal and final evaluation. The results of the research show that this community service activity can produce crystal powder products from ginger and galangal that are easy, cheap and can help lower blood pressure in the people of Wirun Village. This crystal powder products from traditional plants can be a business opportunity for KWT from Wirun as a Produksi Industri Rumah Tangga (PIRT).
Co-Authors Erindyah Retno Wikantyasning Iwan Setiawan Muhtadi Muhtadi Retnowati Adiningsih