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All Journal Indonesian Journal of Cancer Chemoprevention Pharmacon Pharmascience CERATA Jurnal Ilmu Farmasi Abdimas Galuh : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Global Health research I-Com : Indonesian Community Journal Abdi Geomedisains Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Proceeding ISETH (International Summit on Science, Technology, and Humanity) CERATA
Erindyah Retno Wikantyasning
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Formulasi dan Karakterisasi Sediaan Nanoemulgel Serbuk Lidah Buaya (Aloe Vera L.) Imanto, Teguh; Prasetiawan, Roseh; Wikantyasning, Erindyah Retno
Pharmacon: Jurnal Farmasi Indonesia Vol 16, No 1 (2019)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v16i1.8114

Abstract

Aloe vera L. contains antiseptic saponins and anthraquinone complexes as antibacterial. This research was conducted to formulate aloe vera powder into nanoemulgel, characterize and test its physical properties, and to know the effect of gelling agent concentration (carbopol and chitosan) on nanoemulgel. Emulsion type used is oil in water (O / W) with surfactant tween 80 and co-surfactant propylene glycol. Nanoemulsion is characterized by percent of transmittance with UV-Vis spectrophotometer, also potential droplet and zeta size distribution with Particle Size Analyzer. Hydrogels consist of 4 combination formulas of carbopol 0.5%; 1%; 1.5%; 2% and 0.3% chitosan. The formula is tested for physical properties including organoleptic, pH, spreadability, adhesion, viscosity and stability with freeze thaw method. The results showed that the nanoemulsion droplet size was 65.05nm ± 13.49 with zeta potential of -0.1mV and the percent of transmittance above 98%. The result of physical properties of the four formulas shows that the different gelling agent concentration gives different physical properties of viscosity and spreadability. Overall, formula 3 has the best physical properties and physical stability compared to formula 1, 2 and 4.
Optimasi Formulasi Esens Sheet Mask Kombinasi Ekstrak Spirulina platensis dan Nanopartikel Bentonit dengan Metode Simplex Lattice Design Wikantyasning, Erindyah Retno; Nurhakimah, Ulil Fikri; Sula, Ramadhani Dwi; Astuti, Kartika Fidi
Pharmacon: Jurnal Farmasi Indonesia Vol 16, No 1 (2019)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v16i1.8307

Abstract

Spirulina platensis contained phycocyanin that has the potential for antioxidant activity. Bentonite contains various minerals that can absorb water and was known having ability for scavenging of free radicals. The purpose of this study was to obtain the optimum formulae of sheet mask essence, containing combination of Spirulina platensis extract and bentonite nanoparticles and evaluated the antioxidant activity using DPPH (2,2-diphenyl-1-pikrihidrazil) assay. Bentonite nanoparticles was prepared by High Energy Milling (HEM) method and characterized using Particle Size Analyzer (PSA). The results of the nanoparticles characterization was 152,8±0,69 nm for the particle size and 0.106±0.03 for PI value. Physical stability tests showed that the formula was homogenous, viscosity between 0.7-1.1 dPas, and pH between 5-6.5. The IC50 value of Spirulina platensis extract was 256.46 ppm with AAI category was medium. The antioxidant test of this fomula that contain Spirulina platensis extract and bentonite nanoparticles did not show any potential antioxidant activity. The concentrations of PEG 400 and Tween 80 were used to formulate the optimum formula were 4.29% w/w and 6.71% w/w.
FRONT MATTERS VOL.17 NO.1 Wikantyasning, Erindyah Retno
Pharmacon: Jurnal Farmasi Indonesia Vol 17, No 1 (2020)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v17i1.11492

Abstract

Edisi Khusus: RAKERDA, SEMINAR, PD IAI JATENG Wikantyasning, Erindyah Retno
Pharmacon: Jurnal Farmasi Indonesia Edisi Khusus: RAKERDA, SEMINAR, PID IAI
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v0i0.11443

Abstract

Front Matters Vol 17, No 2, 2020 Wikantyasning, Erindyah
Pharmacon: Jurnal Farmasi Indonesia Vol 17, No 2 (2020)
Publisher : Universitas Muhammadiyah Surakarta

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Abstract

Optimisasi Tween 80 dan Span 80 Sebagai Emulgator dalam Formula Krim Tabir Surya Kombinasi Ekstrak Etanol Daun Alpukat (Persea americana M.) dan Nanopartikel Seng Oksida Dengan Metode Simplex Lattice Design Erindyah Retno Wikantyasning; Nabilla Indianie
CERATA Jurnal Ilmu Farmasi Vol 12 No 1 (2021): Cerata Jurnal Ilmu Farmasi
Publisher : STIKES MUHAMMADIYAH KLATEN

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Abstract

Avocado leaves contain flavonoid which act as antioxidant whereas nanoparticles of zinc oxide can protect the skin against a wide spectrum of UV. The purpose of this study was to determine the effect of variation of Tween 80 and span 80 as emulsifier and determine the optimum formula of sunscreen scream containing ethanol extract of avocado leaves and zinc oxide nanoparticles. Avocado leaves were extracted by maceration method using ethanol. Nano zinc oxide is obtained by the High Energy Ball Milling technique and characterized using Particle Size Analyzer. Determination of the optimal cream formula with variations in the concentration of Tween 80 and Span 80 is done by Simplex Lattice Design (SLD) method. The maceration resulted ethanolic extract of avocado leaves with a yield of 34.4%. The synthesised zinc oxide nanoparticles obtained showed 179.47±5.98 nm in diameter. The results showed that increasing concentrations of Tween 80 and decreasing concentration of Span 80 increased spreadability but decreased the viscosity and adhesiveness of creams. The SPF evaluation of creams showed a medium protection category (SPF>15). The optimum formula was obtained with the ratio of Tween 80 and Span 80 was 7,8 and 3,2%, respectively, with the desirability value of 0.863.
Penyuluhan DAGUSIBU dan Penggunaan TOGA Pada Hipertensi Kepada Anggota PKK Danukusuman, Kecamatan Serengan, Kota Surakarta Erindyah R. Wikantyasning; Shafira Widyanti; Amalia Septianawati; Nor Laili; Devita Dwitama Setya; Sella Aprilia; Lusi Anggraini
Abdi Geomedisains Vol. 1, No. 1, July 2020
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.407 KB) | DOI: 10.23917/abdigeomedisains.v1i1.95

Abstract

Hipertensi merupakan salah satu penyakit tidak menular yang menjadi ancaman masyarakat di negara berkembang. Hipertensi disebut silent killer karena gejala yang dialami penderita hampir sama dengan gejala penyakit lain atau tanpa keluhan, sehinga tidak diketahui mengalami hipertensi dan baru diketahui setelah terjadi komplikasi. Danukusuman merupakan kawasan padat penduduk dengan rata-rata usia lebih dari 40 tahun dengan pekerjaan sebagai wirausaha. Penduduk di Danukusuman sebagian mengalami hipertensi. Obat hipertensi digunakan oleh sebagian kecil penduduk, sedangkan sebagian besar tidak mengkonsumsi obat karena takut ketergantungan dalam pengobatan. Selain itu TOGA (tanaman obat keluarga) sebagai pencegahan hipertensi belum diminati di kalangan penduduk Danukusuman. Tujuan kegiatan ini adalah untuk mensosialisasikan tentang penyakit hipertensi, gerakan DAGUSIBU (dapatkan, gunakan, simpan, buang) untuk obat hipertensi, dan pengendalian hipertensi menggunakan TOGA. Kegiatan pengabdian masyarakat untuk ibu-ibu PKK Danukusuman dilaksanakan pada hari minggu tanggal 22 Desember 2019. Kegiatan dilakukan dengan pemberian pretest, pengecekan tekanan darah, penyuluhan tentang hipertensi, DAGUSIBU, tanaman obat keluarga untuk hipertensi, diskusi, dan post test. Dari analisis hasil pretest dan post test diketahui adanya peningkatan yang signifikan tentang pengetahuan ibu-ibu PKK mengenai materi yang disampaikan. Dari kegiatan ini diharapkan adanya keberlanjutan yaitu adanya tindakan pengendalian hipertensi yang lebih baik di kalangan ibu-ibu PKK kelurahan Danukusuman Surakarta.
Front Matters Vol.18, No 1, 2021 Erindyah Retno Wikantyasning
Pharmacon: Jurnal Farmasi Indonesia Vol 18, No 1 (2021)
Publisher : Universitas Muhammadiyah Surakarta

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Abstract

Front Matters Vol 16 No 2 (2019) Erindyah Retno Wikantyasning
Pharmacon: Jurnal Farmasi Indonesia Vol 16, No 2 (2019)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v16i2.9785

Abstract

Formulasi dan Karakterisasi Sediaan Nanoemulgel Serbuk Lidah Buaya (Aloe Vera L.) Teguh Imanto; Roseh Prasetiawan; Erindyah Retno Wikantyasning
Pharmacon: Jurnal Farmasi Indonesia Vol 16, No 1 (2019)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v16i1.8114

Abstract

Aloe vera L. contains antiseptic saponins and anthraquinone complexes as antibacterial. This research was conducted to formulate aloe vera powder into nanoemulgel, characterize and test its physical properties, and to know the effect of gelling agent concentration (carbopol and chitosan) on nanoemulgel. Emulsion type used is oil in water (O / W) with surfactant tween 80 and co-surfactant propylene glycol. Nanoemulsion is characterized by percent of transmittance with UV-Vis spectrophotometer, also potential droplet and zeta size distribution with Particle Size Analyzer. Hydrogels consist of 4 combination formulas of carbopol 0.5%; 1%; 1.5%; 2% and 0.3% chitosan. The formula is tested for physical properties including organoleptic, pH, spreadability, adhesion, viscosity and stability with freeze thaw method. The results showed that the nanoemulsion droplet size was 65.05nm ± 13.49 with zeta potential of -0.1mV and the percent of transmittance above 98%. The result of physical properties of the four formulas shows that the different gelling agent concentration gives different physical properties of viscosity and spreadability. Overall, formula 3 has the best physical properties and physical stability compared to formula 1, 2 and 4.
Co-Authors Amalia Septianawati Amanda Wahyu Kurniawan Ambar Yunita Ambar Yunita Nugraheni Andi Suhendi Arifah Sri Wahyuni Astuti, Kartika Fidi Audi Tahta Aurellia Brainandiva Ade Fitria Cahya Rahma Utami Cholisoh, Zakky Dedi Hanwar Devita Dwitama Setya Dzaki Fikri Firdaus Bakri Endang Setyaningsih Gayuh Ilham Rahmadi Gunawan Setyadi Hidayah Karuniawati Ika Ayu Mentari Ika Trisharyanti Indah Hairunisa Indana Lazulfa Kartika Fidi Astuti Khoirunnisa Khoirunnisa Luluk Ria Rakhma Lusi Anggraini Muhammad Da'i Muhammad Ikhsan Al Af Ghani Muhtadi Muhtadi Nabilla Indianie Nor Laili Nurhakimah, Ulil Fikri Prasetiawan, Roseh Ramadhani Dwi Sula Refsya Azanti Rima Munawaroh Riyan Eko Hartanto Roseh Prasetiawan Rosi Hayyu Anjani Salsabila Azzahra Sania Nayasari Khoirunnisa Sella Aprilia Setyo Nurwaini Shafira Widyanti Sula, Ramadhani Dwi Teguh Imanto Tribudi Julianti Ulil Fikri Nurhakimah Yuka Aulia Rahma