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All Journal Jurnal Biologi Tropis Journal of Social Science
Trisna Ayu Kurnia Putri
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Physics Social Sciences

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Understanding and Addressing the Challenges of Gastrointestinal Stromal Tumor (GIST): Towards Improved Diagnosis and Treatment Strategies Ali Ramzi; Alma Dyah Perwita; Dinda Salsabila; Trisna Ayu Kurnia Putri; Ulul Azmi
Journal of Social Science Vol. 4 No. 5 (2023): Journal of Social Science
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jss.v4i5.705

Abstract

Gastrointestinal stromal tumor (GIST) is a prevalent mesenchymal tumor affecting the digestive tract, with the stomach being the most common location. While some GIST cases are sporadic with no known risk factors, certain factors like age and genetic abnormalities increase the risk. Early diagnosis of GIST remains challenging due to atypical symptoms, leading to late diagnoses and reduced survival rates. This research aims to identify specific risk factors related to local populations, develop accurate early diagnosis methods, and formulate more effective treatment strategies. The study involves a retrospective observational approach, collecting data from medical records of GIST patients and analyzing risk factors and treatment outcomes. The results highlight the increasing prevalence of GIST globally, emphasizing the need for increased awareness and early diagnosis. Challenges in early diagnosis and treatment underscore the importance of public awareness, medical education, and collaborative efforts for better GIST management. This research offers implications for the development of diagnostic guidelines and more effective treatment approaches, ultimately improving the prognosis and quality of life for GIST patients.
Facial Palsy Treatment After Cranial Base Fracture : A Systematic Review Suci Nurjanah; Wardha Novia; Trisna Ayu Kurnia Putri; Sima Smith; Ni Made Shinta Dewi; Ulul Azmi; Bambang Priyanto
Jurnal Biologi Tropis Vol. 23 No. 4 (2023): October - December
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i4.5755

Abstract

Facial nerve paralysis is a common event in cases of cranial base trauma. Especially facial nerve paralysis due to trauma or fracture of the temporal bone accounts for around 7-10% of cases. Analysis of studies related to the management of facial nerve paralysis due to skull base fractures still needs to be studied. The aim of this paper is to examine in more depth the management of facial nerve paralysis due to traumatic skull base fractures. This research analyzes studies through the PubMed, Google Scholar, and Proquest databases. After searching, 729 articles were found. Seven articles were found that were suitable and discussed the management of facial nerve paralysis due to cranial base trauma. Based on the results of the investigation, it was found that the management carried out was based on the severity scale of facial paralysis where medical or surgical treatment could be carried out according to the required indications.
Meningioma: A Literature Review Trisna Ayu Kurnia Putri; Lale Maulin Prihatin; Bambang Priyanto
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.5784

Abstract

Meningioma is the most common type of the central nervous system tumor. South East Asia is the third highest cases of central nervous system tumor with 190,376 cases every year. The majority of meningioma cases are benign, although few of the cases requires a lot more significant treatment in order to survive. Although meningiomas with complicated histopathology and/or in tricky locations can be challenging for surgeons to treat. The earlier we detect and handle brain tumor, the better the prognosis outcome for the patient. Method used in this paper is literature review. Review made by finding and curating literatures regarding meningioma on online databases such as PubMed, Google Scholar, and Proquest. This paper summarizes the current epidemiology, etiology, histopathology, pathology, diagnosis, and the current treatments available for meningioma.
Giant Cell Tumor: Pathogenesis and Clinical Manifestation Adinda Ilsa Maulida; Ali Ramzi; Amrullah Muliawan H; Baiq Ghassani Kayla; Clara Nadila; Dinda Salsabila; Febbi Anggy; Herodya Lajunee Fesmia; Jihan Alifa Rahma; Trisna Ayu Kurnia Putri; Wina Aryslia Fakar; Zulfa Hasyimiyyah Ihtisyam; Nurhidayati Nurhidayati
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i4b.5831

Abstract

A giant cell tumor of bone (GCTB) as known as a benign bone tumor (neoplasm) is aggressive locally and frequently recurs, and it is characterized by the growth of mononuclear stromal cells and datia cells that resemble osteoclasts. GCTB has varying incidence rates and has been shown to have high mortality. GCTB patients have several treatment options, but the majority of patients still experience recurrence and even metastasis to other organs. This literature review aims to explain more deeply about Giant Cell Tumor (GCT) starting from the definition, etiology, epidemiology, pathogenesis, clinical manifestations and treatment options so that patients get a better prognosis. This literature review was conducted using the keywords "Giant Cell Tumor AND pathogenesis AND clinical manifestation" from PubMed dan Google Scholar. The results of the literature review carried out are that the molecular and biological pathogenesis of GCTB consists of 4 processes, namely tumorigenesis of neoplastic mononuclear stromal cells, generation of reactive multinucleated giant cells, bone resorption/migration, and bone matrix remodeling for angiogenesis, invasiveness, and metastasis. Besides, the histological picture of GCTB contains "reactive" osteoclasts such as multinucleated giant cells (Giant Cells/GC), round cells such as macrophages and spindle stromal cells such as "neoplastic" fibroblasts (mononuclear stromal cells/SC) which are important findings in establishing the diagnosis. In conclusion, staging and management are very important to produce a better prognosis and reduce recurrence rates in GCTB patients.
Co-Authors Adinda Ilsa Maulida Ali Ramzi Alma Dyah Perwita Amrullah Muliawan H Baiq Ghassani Kayla Bambang Priyanto Clara Nadila Dinda Salsabila Febbi Anggy Herodya Lajunee Fesmia Jihan Alifa Rahma Lale Maulin Prihatin Ni Made Shinta Dewi Nurhidayati Nurhidayati Sima Smith Suci Nurjanah Ulul Azmi Wardha Novia Wina Aryslia Fakar Zulfa Hasyimiyyah Ihtisyam