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All Journal Journal of Islamic Pharmacy Journals of Ners Community Journal of Tropical Pharmacy and Chemistry Lumbung Farmasi : Jurnal Ilmu Kefarmasian jurnal penelitian multidisiplin
Yazid, Edy Agustian
Akademi Analis Kesehatan Delima Husada Gresik
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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REDUCTION OF FORMALDEHYDE LEVELS IN TOFU USING WHITE TURMERIC (Curcuma mango) WITH SPECTROPHOTOMETRY Yazid, Edy Agustian; Putri, Evariza Vyanto
Journal of Islamic Pharmacy Vol 2, No 2 (2017): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v2i2.4505

Abstract

Tofu is a type of traditional food that is widely consumed by the community. Tofu is susceptible to damage so manufacturers know often add preservatives such as formaldehyde. Formaldehyde or known as formalin is not included in the list of food additives as they are toxic and harmful to human health. This study aims to determine the decrease in formalin content in tofu using the addition of white turmeric. The method used by spectrophotometry with chromatropic acid as reagent and absorbance is measured at a wavelength of 570 nm. Based on the research results obtained formalin level on tofu before added white turmeric equal to 10.279 ppm. After addition of white turmeric solution with concentration 2.5%; 5% and 7.5%, respectively with soaking for 5 minutes, 10 minutes and 15 minutes obtained the largest decrease of formalin at 7.5% concentration for 15 minutes at 62.8%. From these results it can be concluded that with the addition of white turmeric can reduce formalin in tofu. Keywords : Tofu, Formaldehyde, White Turmeric, Spectrophotometry 
LIPASE ACTIVITIY OF MIXTURE OF FERMENTED AVOCADO (Persea americana), BANANA (Moses paradisiaca) AND SNAKEFRUIT (Salacca zalacca) Yazid, Edy Agustian
Journal of Islamic Pharmacy Vol 2, No 1 (2017): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v2i1.4252

Abstract

Fermentation is one of the bioconversion processes to produce anaerobic microbes which are beneficial and can produce enzymes. One of the enzymes that can be produced is lipase. Mixed fruit fermentation is an effort to produce lipase that can be done simply. The purpose of this research is to know the activity of lipase enzyme from mixture of fermented avocado fruit (Persea americana), bananas (Musa paradisiaca) and snakefruit (Salacca zalacca). Lipase enzyme activity is tested by measuring of free fatty acid (FFA) content obtained from olive oil hydrolysis process by lipase enzyme. The results showed the highest activity obtained 17.425 U/ml and the percentage of FFA produced was 12.94%. The highest activity of lipase enzyme was obtained at 450C and pH 6.5. From this research can be concluded that the fermentation of the mixture of avocado, bananas and snakefruit can produce lipase enzyme that has relatively high activity. Keywords: Enzyme Activity, Fruits, Fermentation, Lipase. 
DETERMINATION OF THIAMINE HYDROCHLORIDE AND PYRIDOXINE HYDROCHLORIDE ON RICE WITH WASHING, MILLING AND POUNDING BY SPECTROMETRIC METHODS Yazid, Edy Agustian; Ati, Damar Pasunaring; Mahardika, Aulia
Journal of Islamic Pharmacy Vol 3, No 2 (2018): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v3i2.6136

Abstract

Rice is a principal food source for most of the world's population. Rice has many nutrients including thiamin hydrocloride (THC) and pyrodoxine hydrocloride (PHC). Before consumption, rice is usually processed such as milling, washing, and cooking. Determination of THC on IR-64 and Rojolele rice with washing three times has been conducted. Also determined of PHC on the milled IR-64 rice and the pounded IR-64 rice. The THC was determined by spectrophotometric method at 246 nm. Determination of PHC based on the coupling reaction with diazo reagent in alkaline solution to form azo dye then the absorption was measured at 440 nm. The result of determination of THC on IR-64 and Rojolele rice after washing three times can decrease THC level 12,93% and 12,88% respectively. Determination of PHC on the milled IR-64 rice obtained 1.54 ± 0.027 mg/g and on the pounded IR-64 rice 1.80 ± 0.048 mg/g. The result of statistical test with independent T test showed there were significant difference (α = 0,05) PHC level on both treatments.
Techniques for Reducing Iron (Fe) Content in Groundwater: an Article Review Yazid, Edy Agustian; Wafi, Abdul; Saraswati, Arina
Journal of Islamic Pharmacy Vol 6, No 1 (2021): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v6i1.12078

Abstract

Iron is a chemical element that is found in almost every place on earth, including in well water or groundwater. Iron can be suspended in water with organic substances or inorganic solids in the form of ferrous cations (Fe2+) and ferries (Fe3+). The presence of iron that exceeds the threshold can cause detrimental effects such as corrosion of the piping, the color of the water turns brown, smells bad, and can cause health problems. The iron content in groundwater can be reduced so that it can be used as water that is fit for consumption or use in everyday life. This study aims to determine several types of techniques used to reduce iron in groundwater or well water through literature studies. Techniques covered include filtration, aeration, adsorption, coagulation, electrocoagulation, and cascade aerators. The results showed that the greatest reduction in efficiency was found in the combination type of adsorption technique and filtration technique by more than 99.1%, then followed by the electrocoagulation technique of  99.74%. From all the techniques studied in this study, it can be concluded that all techniques can reduce iron levels in which the combination of adsorption and filtration techniques is the most effective.Keywords: Technique, reduction, iron content, groundwater
Perbedaan Kadar Kolesterol pada Akseptor KB Pil dan KB Suntik Menggunakan Metode Stick Edy Agustian Yazid; Nahdia Karina Putri
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 3, No 2 (2022): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v3i2.9389

Abstract

ABSTRAKMasyarakat Indonesia umumnya menggunakan alat kontrasepsi untuk menunda kehamilan. Kontrasepsi pil dan suntik adalah kontrasepsi hormonal yang populer dan sangat efektif. Selain bermanfaat, kontrasepsi hormonal juga memiliki efek samping bagi akseptornya. Penelitian ini bertujuan untuk mengetahui ada tidaknya perbedaan kadar kolesterol pada akseptor KB pil dan suntik di Desa Beton Menganti Kabupaten Gresik. Penelitian dengan metode stick, memiliki keunggulan lebih praktis dan hanya dirancang untuk pemeriksaan darah kapiler. Hasil pemeriksaan menunjukkan rata-rata kadar kolesterol akseptor KB pil adalah 207 mg/dl dan akseptor KB suntik 177 mg/dl. Persentase kadar kolesterol normal pada akseptor KB pil adalah 34%, batas tertinggi 46% dan tertinggi 20%. Sedangkan persentase kadar kolesterol normal pada akseptor KB suntik 73%, batas tertinggi 7% dan tertinggi 20%. Hasil analisis data menggunakan Paired T-test diperoleh t hitung 1,030 dengan sig 0,320 (sig>0,05), sehingga disimpulkan tidak ada perbedaan kadar kolesterol antar akseptor KB pil dan KB suntik. Kata kunci :  Kolesterol; KB pil; KB suntik; Metode stick.ANSTRACTIndonesian people generally use contraception to delay pregnancy. Pill and injectable contraceptives are popular and highly effective hormonal contraceptives. Besides being useful, hormonal contraception also has side effects for the acceptor. This study aims to determine whether there are differences in cholesterol levels in pill and injection family planning acceptors in Beton Menganti Village, Gresik Regency. Research using the stick method, has the advantage of being more practical and only designed for capillary blood examination. The results of the examination showed that the average cholesterol level of the contraceptive pill KB acceptor was 207 mg/dl and the injection KB acceptor was 177 mg/dl. The percentage of normal cholesterol levels for the acceptors of pills KB is 33%, the highest limit is 47% and the highest is 20%. Meanwhile, the percentage of normal cholesterol levels for injectable acceptors KB is 73%, the high limit is 7% and the highest is 20%. The results of data analysis using Paired T-test obtained t count 1.030 with sig 0.320 (sig>0.05), so that it was concluded that there was no difference in cholesterol levels between pill and injection KB acceptors. Keywords : Cholesterol; Pill KB; Injectable KB; Stick Method.
KADAR PROTEIN TERLARUT PADA AMPAS KEDELAI DARI HASIL PROSES PEMBUATAN TEMPE DENGAN PENAMBAHAN EKSTRAK KASAR PAPAIN (CRUDE PAPAIN) Dissolved Protein Content in Soybean Dregs From The Process Of Making Tempe With The Addition Of Crude Papain Extract Edy Agustian Yazid; Badilatun Ulin Nuha
Journals of Ners Community Vol 8 No 1 (2017): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.194 KB) | DOI: 10.5281/j ners community.v8i1.285

Abstract

Ampas kedelai dari proses pembuatan tempe umumnya masih mengandung nilai nutrisi cukup tinggi diantaranya protein. Selama ini ampas kedelai belum dimanfaatkan secara maksimal, kebanyakan hanya digunakan sebagai pakan ternak atau pupuk. Tujuan penelitian ini adalah untuk mengetahui kandungan protein terlarut pada ampas kedelai dari hasil proses pembuatan tempe dengan penambahan ekstrak kasar papain (crude papain). Analisis kadar protein dilakukan menggunakan metode spektrofotometri UV-Vis dengan panjang gelombang 650 nm. Variasi konsentrasi papain yang ditambahkan adalah 0% (kontrol), 5%, 10%, 15%, 20% dan 25%. Hasil uji aktivitas papain kasar didapatkan 238,082 U/ml, sedangkan pada penambahan konsentrasi papain 5%, 10%, 15%, 20%, dan 25% berturut-turut diperoleh kenaikan kadar protein terlarut sebesar 0,42%; 2,53%; 4,77%; 4,63% dan 3,93%. Hasil penelitian menunjukkan bahwa dengan penambahan ekstrak kasar papain pada ampas kedelai dari hasil proses pembuatan tempe dapat menaikkan kadar protein terlarut. Kenaikan tertinggi diperoleh pada penambahan konsentrasi papain 15% dengan kenaikan sebesar 4,77%. Kata Kunci : Ampas kedelai, protein terlarut, crude papain, aktivitas enzim. The soybean dregs from process of making tempe generally still contains high nutritional value of protein. So far, soybean dregs has not been fully utilized, mostly only used as animal feed or fertilizer. The purpose of this study was to determine the dissolved protein content in soybean dregs from the process of making tempe with the addition of crude papain extract (crude papain). The protein content was analyzed using spectrofotometry UV-Vis method with 650 nm wavelength. Variations of papain concentration added were 0% (control), 5%, 10%, 15%, 20% and 25%. The results of crude papain extract activity test were obtained 238,082 U/ml, while with the addition of papain concentration 5%, 10%, 15%, 20%, and 25% dissolved protein content increased respectively 0.12%; 2.53%; 4.77%; 4.63% and 3.93%. From these results it can be concluded that with the addition of crude papain extract on soybean dregs from the process of making tempe can raise the levels of dissolved protein. The highest increase was obtained by adding 15% papain concentration with an increase of 4.77%. Keywords : Soybean dregs, soluble protein, crude papain, enzyme activity. DOI: 10.5281/zenodo.1409293
Analysis of Caffeine in Tablet Dosage Form with Spectrophotometric and Iodometric Back Titration Methods Edy Agustian Yazid
Journal of Tropical Pharmacy and Chemistry Vol. 4 No. 6 (2019): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v4i6.214

Abstract

Caffeine (1, 3, 5-trimethylxanthine) is an active ingredient that is often added to analgesics drugs to teat headaches or reduce pain. This study aims to quantitatively analyze caffeine levels in tablet dosage forms by spectrophotometric methods and iodometric back titration. In the spectrophotometric method the measurement of caffeine levels was carried out using a maximum wavelength of 272 nm.The results of caffeine levels were found for bodrex drugs (50.87 ± 0.195 mg/tab), extra panadol (64.92 ± 0.579 mg/tab), saridon (51.38 ± 0.273 mg/tab) and paramex (46.78 ± 0.072 mg/tab). The purity percentage of caffeine was found in the range between 93.57-102.76%. While the iodometric back titration method was obtained for bodrex (48.04 ± 0.889 mg/tab), extra panadol (64.45 ± 0.697 mg/tab), saridon (43.38 ± 0.756 mg/tab) and paramex (42.36 ± 0.889 mg/tab) with a purity range of 84.73-99.15%. The average caffeine content of the two method extant suitability close to the true value as stated on the label. The results of the spectrophotometric method are more accurate, while the titrimetry method is still good to use because it is cheaper and only requires simple apparatus and common chemicals.
Spectrophotometric Methods for the Determination of Caffeine in Beverages Use Solvent Extraction Techniques and Adsorption of Activated Carbon Edy Agustian Yazid; Abdul Wafi; Agustin Eka Wulandari
Journal of Tropical Pharmacy and Chemistry Vol. 5 No. 4 (2021): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v5i4.308

Abstract

Kafein memiliki kegunaan terapeutik yang luas, banyak digunakan di bidang farmasi sebagai analgesik, dan mengurangi demam. Kafein juga banyak ditambahkan sebagai zat penyedap pada minuman ringan seperti coca cola dan minuman energi. Konsumsi kafein yang berlebihan atau dalam jangka panjang dapat berdampak negatif bagi kesehatan. Kandungan kafein dalam minuman bervariasi menurut mereknya, dari 10 hingga 50 mg per porsi. Penelitian ini bertujuan untuk mengetahui jumlah kafein dalam minuman berkarbonasi dan minuman energi dengan menggunakan teknik ekstraksi pelarut kloroform dan teknik adsorpsi karbon aktif. Kadar kafein dalam minuman dianalisis dengan metode spektrofotometri menggunakan panjang gelombang maksimum. Hasil penelitian menunjukkan bahwa jumlah kafein dengan teknik ekstraksi pada minuman coca cola adalah (31,39 ± 0,528 mg / saji), pepsi biru (27,93 ± 0,159 mg / sajian), banteng merah (39. 79 ± 0,233 mg / porsi), dan macan kumbang (43,37 ± 0,860 mg / porsi). Teknik adsorpsi yang diperoleh pada minuman coca cola adalah (32,07 ± 0,164 mg / saji), pepsi biru (27,42 ± 0,174 mg / saji), banteng merah (31,35 ± 0,132 mg / saji), dan macan kumbang (33,83 ± 0,205 mg / saji) . Pada minuman coca cola, diperoleh hasil terbaik mendekati nilai sebenarnya seperti yang tertera pada label. Sedangkan untuk ketiga jenis minuman lainnya, jumlah kafein yang didapat lebih rendah dari yang diharapkan, dan masih di bawah batas maksimal yang diperbolehkan. Dari dua teknik yang diteliti, teknik ekstraksi masih memberikan hasil yang lebih baik dibandingkan dengan teknik adsorpsi. dan macan kumbang (33,83 ± 0,205 mg / porsi). Pada minuman coca cola, diperoleh hasil terbaik mendekati nilai sebenarnya seperti yang tertera pada label. Sedangkan untuk ketiga jenis minuman lainnya, jumlah kafein yang didapat lebih rendah dari yang diharapkan, dan masih di bawah batas maksimal yang diperbolehkan. Dari dua teknik yang diteliti, teknik ekstraksi masih memberikan hasil yang lebih baik dibandingkan dengan teknik adsorpsi. dan macan kumbang (33,83 ± 0,205 mg / porsi). Pada minuman coca cola, diperoleh hasil terbaik mendekati nilai sebenarnya seperti yang tertera pada label. Sedangkan untuk ketiga jenis minuman lainnya, jumlah kafein yang didapat lebih rendah dari yang diharapkan, dan masih di bawah batas maksimal yang diperbolehkan. Dari dua teknik yang diteliti, teknik ekstraksi masih memberikan hasil yang lebih baik dibandingkan dengan teknik adsorpsi. Kata kunci : Kafein, Minuman, Ekstraksi, Adsorpsi, Spektrofotometri
PERBEDAAN KADAR HEMOGLOBIN SEBELUM DAN SESUDAH DONOR DARAH DENGAN PEMERIKSAAN METODE POCT (Point of Care Testing): Hemoglobin, Blood Donation, POCT Method Rosidah; Retno Twistiandayani; Indah Vauzyana; Edy Agustian Yazid
Jurnal Penelitian Multidisiplin Vol. 1 No. 1 (2022): Jurnal Penelitian Multidisiplin
Publisher : Jurnal Penelitian Multidisiplin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.281 KB)

Abstract

Hemoglobin is a metalloprotein, which is an iron-containing protein in red blood cells that functions as a carrier of oxygen from the lungs throughout the body. Blood donation is the process of transferring blood or blood elements from one person to the circulatory system of another. The purpose of this study was to determine the difference in hemoglobin levels before and after blood donation by examining the POCT (Point of Care Testing) method. The characteristics analyzed were hemoglobin levels before and after blood donation. The results of this study showed that the average hemoglobin level before blood donation was 14,654 gr/dl and the average hemoglobin level after blood donation was 14,289 gr/dl. From the results of data analysis using the SPSS program, the results obtained are sig (2-tailed) 0.002. Because sig (2-tailed) < , 0.002 <0.05, H0 is rejected and H1 is accepted. Thus, the results obtained are that there are differences in hemoglobin levels before and after blood donation using the POCT (Point of Care Testing) method. The difference in the amount of hemoglobin in the donor is caused by several factors, such as gender, age, weight, and others.
Co-Authors Abdul Wafi Abdul Wafi, Abdul Agustin Eka Wulandari Ati, Damar Pasunaring Badilatun Ulin Nuha Indah Vauzyana Mahardika, Aulia Nahdia Karina Putri Putri, Evariza Vyanto Retno Twistiandayani Rosidah Saraswati, Arina