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All Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Jurnal of Community Health Development (JCHD) Medical and Health Journal Molekul: Jurnal Ilmiah Kimia
Yusan, Rizak Tiara
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Veterinary

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DETEKSI DINI PRADIABETIK SEBAGAI LANGKAH AWAL PENCEGAHAN DIABETES MELITUS DI MASYARAKAT PERUMAHAN BUKIT KALIBAGOR INDAH, KECAMATAN KALIBAGOR, KABUPATEN BANYUMAS wahyudin, wahyudin; Yusan, Rizak Tiara; Pratama, Koernia Nanda; Hidayah, Arfi Nurul
Jurnal of Community Health Development Vol 4 No 1 (2023): Vol 4 No 1 (2023): Journal Of Community Health Development terbitan bulan Januari
Publisher : Universitas Jenderal Soedirman, Jurusan Keperawatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.221 KB) | DOI: 10.20884/1.jchd.2023.4.1.7012

Abstract

Deteksi dini pradiabetik merupakan salah satu cara untuk menekan tingginya angka kejadian diabetes yang setiap tahun mengalami peningkatan. Tujuan pengabdian ini adalah untuk mengetahui kondisi gula darah sejak awal warga yang tinggal di perumahan bukit kalibagor indah. Jika kondisinya adalah pradiabetik, maka warga dapat merubah pola kehidupannya menjadi lebih sehat, sehingga kondisi pradiabetik yang dialami tidak berkembang menjadi diabetik. Metode yang digunakan adalah memeriksa gula darah puasa (GDP) warga. Pemeriksaan GDP bekerjasama dengan kader posbindu, ketua RT, tokoh masyarakat dan takmir mesjid yang dilaksanakan pada pagi hari. Selanjutnya dilakukan penyuluhan untuk meningkatkan pengetahuan warga terkait dengan pradiabetik, diabetik, komplikasi, manajemen stress pradiabetik dan diabetik, serta penyuluhan terkait dengan olahraga kaki pada diabetes. Hasil pengabdian menunjukkan bahwa dari 105 warga yang memeriksa GDP, diperoleh hasil bahwa yang mengalami pradiabetik adalah sebanyak 43 %. Jumlah yang tidak sedikit tentunya, mengingat banyak warga yang takut memeriksakan GDP, sehingga hanya sejumlah 105 warga yang memeriksa GDP. Pelaksanaan penyuluhan menunjukkan peningkatan pengetahuan warga terhadap materi penyuluhan yang diberikan dengan nilai p< 0.05. pengetahuan tentang pradiabetik diharapkan akan menjadi modal untuk merubah pola hidup yang lebih sehat. Key word: pradiabetik, deteksi dini, gula darah puasa (GDP)
The Comparison of Tannin Fractions in Calliandra calothyrsus Leaves Utilizing Butanol-HCl4 and Protein-Precipitation Methods Subagyo, Yusuf; Sumaryadi, Mas Yedi; Ifani, Merryafinola; Widodo, Hermawan Setyo; Yusan, Rizak Tiara
Molekul Vol 19 No 2 (2024)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2024.19.2.8636

Abstract

ABSTRACT. Butanol-HCl4 (Bu-HCl4) and Protein-Precipitation (P-P) are methods that proposed to determine the content of free tannins, protein-bound tannins, and fiber-bound tannins. This study aims to determine the feasibility of tannin measurements by both methods and validation of Analytical Methods (VMA) evaluates specific parameters like accuracy, precision, specificity, and linearity through lab testing. The material used was twenty C. calothyrsus leaves which collected randomly from different trees. The samples were measured by both methods in triplicates for qantification and validation. The obtained data were analyzed by descriptive and t-test to compare both methods. The analysis of VMA shows that the P-P method yields higher accuracy compared to the Bu-HCl method in percentage recovery rates. The quantification of free tannins, protein-bound tannin, tannin fiber, and total tannin by the Bu-HCl4 method versus the P-P method showed significantly higher values (p<0.01) for the Bu-HCl4 method: free tannins (13.44±0.54 vs. 7.11±0.16), protein-bound tannin (2.80±0.44 vs. 1.52±0.20), tannin fiber (5.20±0.45 vs. 1.00±0.21), and total tannin (21.50±0.88 vs. 9.59±0.36). The methode validation result of Bu-HCl4 and P-P methods in the accuracy was different, but the linearity test showed a good response. In conclusion, the tannin quantivication by the P-P and Bu-HCl4 can be applied for C. calothyrsus analysis. The total tannin content was higher if quantified by the Bu-HCl4 method compared to P-P. The accuracy of the P-P found higher than the Bu-HCl4 method. Keywords: Butanol-HCl4, leaves C. calothyrsus, protein-precipitation methods, tannin.
BEETROOT (Beta vulgaris L.) AND ITS POTENTIAL AS AN ANEMIA TREATMENT IN PREGNANCY Fadlilah, Synta Haqqul; Suhartomo, Dalri Muhammad; Yusan, Rizak Tiara; Yudhawan, Indra
Medical and Health Journal Vol 3 No 1 (2023): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2023.3.1.9070

Abstract

Anemia is one of the most common nutritional problems in pregnant women. It is defined as a condition in which the hemoglobin (Hb) level is lower than normal. The main cause of anemia in obstetrics is iron deficiency. To prevent this condition, the Government of Indonesia through the Ministry of Health made a rule by giving iron tablets to pregnant women at least 90 tablets during pregnancy (Kemenkes RI, 2022). However, some people are often bored with this pharmacological therapy due to the nausea and vomiting effect of the iron smell. Therefore, the development of alternative anemia therapy has been done to minimize those problems. One of the herbal ingredients that are being studied for its potential as anti-anemia in pregnancy is beetroot (Beta vulgaris L.). This research is included in the type of literature review. The selected literature is research articles published in the last 10 years (2013 to 2023). There are 10 articles that match the topic of study. A total of 7 publications demonstrated the effect of beetroot on anemia in pregnant women during the pregnancy period, and 2 articles in the post-partum period. A study performed in vivo experiments on pregnant female rats. Almost all of the studies did intervention by giving subjects beetroot juice. Only one study used beets as an intervention as ice cream. The results show that beetroot has the potential to prevent and treat anemia in pregnancy by increasing hemoglobin levels and the amounts of hematocrit. It contains a high level of folic acid which is important for normal cell and tissue growth. The iron content of beetroot also plays an essential role in the human body transporting oxygen to red blood cells, so it helps to cure anemia.
The Potential of Noni (Morinda citrifolia L.) as an Anti-Diabetic Fadlilah, Synta Haqqul; De Silva, Ghea; Suhartomo, Dalri Muhammad; Yusan, Rizak Tiara
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 11, No 1 (2024): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.11.1.2024.83-96

Abstract

Background: Diabetes Mellitus (DM) is still a major health problem in the world today because the prevalence remains increasing. Type 2 diabetes is the most common type of diabetes, accounting for over 90% of all diabetes cases. This disease is characterized by insulin resistance, where the body cannot fully respond to insulin. As a result, glucose levels in the blood continue to increase (hyperglycemia). The main of Type 2 DM management is a healthy lifestyle. In addition, pharmacological therapy is also needed to keep blood glucose levels in diabetics under control. However, antidiabetic medicines can cause some side effects. Therefore, the development of alternative diabetes therapy has been done to minimize side effects. One of the herbal ingredients that are being studied for its potential as an anti-diabetic is noni (Morinda citrifolia L.).Objective: The aim of the study is to review and find out more about the potential of noni (Morinda citrifolia L.) as an anti-diabetic.Methods: This research is included in the type of literature review. The kinds of literature are English and Indonesian language research articles related to the topic searched by using database sources from ProQuest, PubMed, ScienceDirect, and Google Scholar. The research articles were published in the last 10 years (2012 to 2022). Results: There are 14 kinds of literature that match the topic of study. A total of 12 kinds of literature are in vivo studies on animals and 2 literature studies on humans. The result shows that noni has an antidiabetic effect by lowering blood glucose levels and improving other parameters. Parts of Noni that have the potential to control Type 2 DM are fruit and leaves, which can be in the form of extracts, juices, or fermented products. Further research is needed to evaluate the toxicity, the content of active compounds, and the expression of genes related to Type 2 DM for ensuring the mechanism of noni in controlling hyperglycemia. Human studies with more respondents are also needed to confirm the findings of existing studies. Conclusion: Noni has an antidiabetic effect by lowering blood glucose levels and improving other parameters. Based on human studies, noni fruit juice can serve as a suitable addition to the diet of Type 2 DM patients.
Co-Authors De Silva, Ghea Fadlilah, Synta Haqqul Hidayah, Arfi Nurul Ifani, Merryafinola M. Y. Sumaryadi Pratama, Koernia Nanda Suhartomo, Dalri Muhammad Wahyudin Wahyudin Widodo, Hermawan Setyo Yudhawan, Indra Yusuf Subagyo