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Analisis Minimalisasi Biaya Terapi Antihipertensi dengan Kaptopril-Hidroklorotiazid dan Amlodipin-Hidroklorotiazid di Salah Satu Rumah Sakit Kota Bandung Faramitha, Andini; Prihartanto, Budhi; Destiani, Dika P.
Indonesian Journal of Clinical Pharmacy Vol 6, No 3 (2017)
Publisher : Indonesian Journal of Clinical Pharmacy

Keberhasilan terapi hipertensi stage 2 dapat ditunjang dengan adanya pemberian antihipertensi. Beragamnya alternatif terapi antihipertensi menjadikan studi farmakoekonomi diperlukan agar diperoleh terapi yang efektif dan efisien. Tujuan penelitian ini adalah untuk mencari kelompok kombinasi antihipertensi yang lebih efisien dalam hal biaya (minimalisasi biaya) yang digunakan pada pasien hipertensi stage 2 yang dirawat di salah satu rumah sakit swasta Kota Bandung periode tahun 2011â2013. Penelitian ini merupakan studi observasional dengan pengumpulan data secara retrospektif. Pengambilan data dilakukan dengan mengambil rekam medis pasien rawat inap hipertensi stage 2 dan mendapat terapi antihipertensi kaptopril-hidroklorotiazid dan amlodipin-hidroklorotiazid. Komponen biaya yang dikumpulkan meliputi biaya antihipertensi, biaya tindakan, biaya penunjang, biaya rawat inap dan biaya administrasi. Hasil penelitian menunjukkan bahwa total biaya perawatan kombinasi antihipertensi kaptopril-hidroklorotiazid lebih rendah dibandingkan amlodipin-hidroklorotiazid, dengan selisih sebesar Rp126.798.Kata kunci: Antihipertensi, biaya minimal, farmakoekonomi, hipertensiCost Minimization Analysis of Antihypertensive Therapy with Captopril-Hydrochlorothiazide and Amlodipine-HydrochlorothiazideÂ in One of Hospitals in BandungThe successful therapy of stage 2 hypertensionÂ can be supported by the administration of antihypertensive. Existence of various antihypertensive alternative making pharmacoeconomics study is needed in order to have an effective and efficient therapy. Purpose of this study was to find the antihypertensive group therapy which is more efficient in cost (cost minimization) which used in the treatment of stage 2 hypertension in patients at one hospital in Bandung from 2011 until 2013. This study is an observational reserach with retrospective data collection. Data retrieval was done by taking the medical records of hospitalized patients who received therapy of stage 2 hypertension antihypertensive, captopril-hydrochlorothiazide or amlodipin-hydrochlorothiazide. Components that were collected includes the cost of antihypertensive, supportive therapy costs, the cost of action, administrative expenses and cost of hospitalization. The result of this study of cost minimization analysis showed that the total cost of treatment with the antihypertensive captopril-hydrochlorothiazide is lower compared to amlodipin- hydrochlorothiazide, with the difference amounting to Rp126,798.Keywords: Antihypertensive, cost minimization, pharmacoeconomy, hypertension

Effectiveness of Erythropoietin in Hypertensive Hemodialysis Patients Ibrahim, Susannia; Diantini, Ajeng; Prihartanto, Budhi; Supriyadi, Rudi
Pharmacology and Clinical Pharmacy Research Vol 2, No 2
Publisher : Universitas Padjadjaran, Indonesia

Chronic renal failure (CRF) is one the most prevalent health problems among the elderly. Onthe fifth stage of CRF, the patient becomes eligible to hemodialysis. CRF-induced anemiais commonly treated with Erythropoietin (Epo). Information regarding the effectiveness ofEpo in hypertensive hemodialysis patients was limited. Therefore, this study was conductedto evaluate the effectiveness of Epo in hypertensive hemodialysis patients. This study usedan observational case-control analytic method. Data were retrieved from the medical recordsof hemodialysis patients during March-May 2014. A total of 54 participants were included.The increase of haemoglobin (Hb) in controlled hypertension was 0.6257 g/dl, while the inuncontrolled hypertension group, there was a decrease in Hb (-0.1590 g/dl). The use of Epowas more effective in hemodialysis patients with controlled hypertension.Keywords: chronic kidney disease, erythropoietin, hypertension

Analisis Minimalisasi Biaya Terapi Antihipertensi dengan Kaptopril-Hidroklorotiazid dan Amlodipin-Hidroklorotiazid di Salah Satu Rumah Sakit Kota Bandung Andini Faramitha; Budhi Prihartanto; Dika P. Destiani
Indonesian Journal of Clinical Pharmacy Vol 6, No 3 (2017)
Publisher : Universitas Padjadjaran

Keberhasilan terapi hipertensi stage 2 dapat ditunjang dengan adanya pemberian antihipertensi. Beragamnya alternatif terapi antihipertensi menjadikan studi farmakoekonomi diperlukan agar diperoleh terapi yang efektif dan efisien. Tujuan penelitian ini adalah untuk mencari kelompok kombinasi antihipertensi yang lebih efisien dalam hal biaya (minimalisasi biaya) yang digunakan pada pasien hipertensi stage 2 yang dirawat di salah satu rumah sakit swasta Kota Bandung periode tahun 2011–2013. Penelitian ini merupakan studi observasional dengan pengumpulan data secara retrospektif. Pengambilan data dilakukan dengan mengambil rekam medis pasien rawat inap hipertensi stage 2 dan mendapat terapi antihipertensi kaptopril-hidroklorotiazid dan amlodipin-hidroklorotiazid. Komponen biaya yang dikumpulkan meliputi biaya antihipertensi, biaya tindakan, biaya penunjang, biaya rawat inap dan biaya administrasi. Hasil penelitian menunjukkan bahwa total biaya perawatan kombinasi antihipertensi kaptopril-hidroklorotiazid lebih rendah dibandingkan amlodipin-hidroklorotiazid, dengan selisih sebesar Rp126.798.Kata kunci: Antihipertensi, biaya minimal, farmakoekonomi, hipertensiCost Minimization Analysis of Antihypertensive Therapy with Captopril-Hydrochlorothiazide and Amlodipine-Hydrochlorothiazide in One of Hospitals in BandungThe successful therapy of stage 2 hypertension can be supported by the administration of antihypertensive. Existence of various antihypertensive alternative making pharmacoeconomics study is needed in order to have an effective and efficient therapy. Purpose of this study was to find the antihypertensive group therapy which is more efficient in cost (cost minimization) which used in the treatment of stage 2 hypertension in patients at one hospital in Bandung from 2011 until 2013. This study is an observational reserach with retrospective data collection. Data retrieval was done by taking the medical records of hospitalized patients who received therapy of stage 2 hypertension antihypertensive, captopril-hydrochlorothiazide or amlodipin-hydrochlorothiazide. Components that were collected includes the cost of antihypertensive, supportive therapy costs, the cost of action, administrative expenses and cost of hospitalization. The result of this study of cost minimization analysis showed that the total cost of treatment with the antihypertensive captopril-hydrochlorothiazide is lower compared to amlodipin- hydrochlorothiazide, with the difference amounting to Rp126,798.Keywords: Antihypertensive, cost minimization, pharmacoeconomy, hypertension

Effectiveness of Erythropoietin in Hypertensive Hemodialysis Patients Susannia Ibrahim; Ajeng Diantini; Budhi Prihartanto; Rudi Supriyadi
Pharmacology and Clinical Pharmacy Research Vol 2, No 2
Publisher : Universitas Padjadjaran, Indonesia

Chronic renal failure (CRF) is one the most prevalent health problems among the elderly. Onthe fifth stage of CRF, the patient becomes eligible to hemodialysis. CRF-induced anemiais commonly treated with Erythropoietin (Epo). Information regarding the effectiveness ofEpo in hypertensive hemodialysis patients was limited. Therefore, this study was conductedto evaluate the effectiveness of Epo in hypertensive hemodialysis patients. This study usedan observational case-control analytic method. Data were retrieved from the medical recordsof hemodialysis patients during March-May 2014. A total of 54 participants were included.The increase of haemoglobin (Hb) in controlled hypertension was 0.6257 g/dl, while the inuncontrolled hypertension group, there was a decrease in Hb (-0.1590 g/dl). The use of Epowas more effective in hemodialysis patients with controlled hypertension.Keywords: chronic kidney disease, erythropoietin, hypertension

Pengaruh Konseling Farmasi Terhadap Kualitas Hidup Pasien Gagal Ginjal Kronik Dengan Terapi Hemodialisis di RSUD Cibabat Faizatun Maulida; Eli Halimah; Sri Hartini; Budhi Prihartanto
Farmaka Vol 18, No 4 (2020): Farmaka (Suplemen)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/farmaka.v18i4.42268

Penyakit Ginjal Kronis (PGK) adalah masalah kesehatan di seluruh dunia dengan peningkatan prevalensi penyakit, biaya pengobatan, morbiditas dan mortalitas yang tinggi. Pasien gagal ginjal kronis (GGK) dengan terapi hemodialisis membutuhkan terapi jangka panjang dan seumur hidup. Hal tersebut dapat mempengaruhi kualitas hidup pasien. Tujuan penelitian ini adalah untuk mengetahui pengaruh konseling terhadap kualitas hidup pasien GGK dengan terapi hemodialisis di RSUD Cibabat kota Cimahi yang dilaksanakan pada bulan Maret sampai April 2019. Penelitian ini menggunakan pre experimental study one group pre test and post test design. Jumlah sampel yang memenuhi kriteria inklusi sebanyak 62 sampel. Kualitas hidup akan diukur dengan menggunakan kuisioner EQ5D5L sebelum dan setelah konseling. Nilai utilitas sebelum konseling 0,75±0,18 dan setelah konseling 0,82±0,18. Sementara untuk perubahan skor EQ5D Visual Analog Scale (VAS) sebelum konseling adalah 3,74±10,21 dan setelah konseling 69,19±11,53. Hasil penelitian ini menunjukkan bahwa perubahan nilai utilitas dan skor EQ5D VAS pasien hemodialisis sebelum dan setelah konseling menunjukkan perbedaan yang bermakna secara signifikan (p<0,05).

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