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PROFIL URINALISIS PASIEN HIPERTENSI DALAM KEHAMILAN Di Bagian Obstetri dan Ginekologi RSUD Ulin Banjarmasin Periode Juni 2021-Mei 2022 Iman, Muhammad Nur; Nizomy, Ihya Ridlo; Rosida, Azma; Armanza, Ferry; Hendriyono, Franciscus Xaverius
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11460

Abstract

Hypertension disorders in pregnancy (HDP) is one of the most common complications in pregnancy forming a triad along with bleeding and infection which are the main causes of maternal and prenatal morbidity and mortality. Urinalysis examination is one of the important laboratory tests in the diagnosis of HDP, especially to identify the presence of preeclampsia which can lead to eclampsia. Through urinalysis it can be seen the presence of protein in the urine which is one of the diagnostic criteria for preeclampsia-eclampsia and assessing kidney function during pregnancy. The purpose of this study was to determine the urinalysis profile of hypertensive patients in pregnancy. This study used an observational research design with a cross-sectional approach, using secondary data from medical records. This study used the entire population according to the inclusion and exclusion criteria. The subjects of this study were 69 patients. The results showed that preeclampsia was the most common type of HDP, namely 122 people (59.2%). Based on the results of urinalysis in Preeclampsia, the results of urinalysis that showed the most positive results were proteinuria, namely Trace 4 people (9.8%), 1+ 10 people (24.4%), 2+ 10 people (24.4%), and 3+ 4 people (9.8%). Whereas in Preeclampsia Superimposed Hypertension showed the same results where proteinuria was the most positive, namely Trace 1 people (5.9%), 1+ 3 people (17.6%), and 2+ 8 people (47.1%).
Effect of Heavy Metal Polluted River Water on Body Weight and Hemoglobin Level in White Rats (Rattus novergicus) Hendriyono, Franciscus Xaverius; Devi, Wivina Riza; Rosida, Azma; Hidayat, Taufiq
Berkala Kedokteran Vol 20, No 1 (2024)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v20i1.18783

Abstract

Contamination of heavy metal on the South Kalimantan River has become a well thrived issue. In the Barito River watershed, it is reported that there are heavy metals in the form of Pb, Hg and Cd. Heavy metals can affect physiological anatomical changes and the hematopoietic system. This study aims to determine the impact of heavy metal contamination on changes in body weight and hemoglobin levels. The research method is a true laboratory experiment using a pre-post-test group design. The subjects used were healthy male white rats (Rattus norvegicus), aged 2-6 months and weighing 250-300 gr. The research group was divided into two groups, the control group (K) was a group of experimental animals that were given distilled water while the treatment group (P) was a group of experimental animals that were given water contaminated with heavy metals (Pb, Cd, and Hg) ad libitum for 30 days. The results showed that there was no effect of giving Pb metal; 0.01 mg/l = 0.006 mg/kgBW, Cd; 0.003 mg/l = 0.018 mg/kgBW, Hg; 0.001 mg/l = 0.0006 mg/kgBW and Pb+Cd+Hg; 0.006 mg/kgBB + 0.018 mg/kgBB + 0.0006 mg/kgBB on body weight of white rats. There was a significant decrease in Hb levels in white rat hemoglobin after administration of Pb metal; 0.01 mg/l = 0.006 mg/kgBB. Pb metal in water can influence changes in decreasing Hb levels during sub-acute administration. It can be concluded that there was a significant difference in hemoglobin levels before and after giving water containing Pb/lead metal, whereas in the other groups there was no significant difference, as did the Hb levels.