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All Journal SRIWIJAYA JOURNAL OF MEDICINE
Singgih, Gregiorio Gavriel
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Correlation Between Neutrophil to Lymphocyte Ratio (NLR) and Patient with Heart Failure: Haematology Variables in Patient with Heart Failure Rinaldi, Fransiskus Xaverius; Lembar, Stefanus; Ridjab, Denio Adrianus; Leonardo, Leonardo; Lauryn, Jessica; Erlina, Erlina; Singgih, Gregiorio Gavriel
Sriwijaya Journal of Medicine Vol. 5 No. 1 (2022): Vol 5, No 1, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/SJM.v5i1.124

Abstract

Heart failure is a condition of the heart that cannot pump blood adequately resulting in systemic tissue hypoperfusion. This situation will cause systemic inflammatory reactions. Neutrophil to Lymphocyte Ratio (NLR) is an inexpensive and easy parameter that can see inflammatory reactions. This research uses descriptive and analytical studies with cross-sectional studies. The number of samples was 67 heart failure patients who were treated at Atma Jaya Hospital. The statistical test used is unpaired T-test to see if there was a correlation between the NLR value in heart failure, after that NLR cut-off point will be analyzed using a receiver operating curve (ROC). Pearson correlation test was conducted to see the correlation of NLR with laboratory results, including haemoglobin, hematocrit, leukocytes, and platelet. The results showed a significant difference of NLR between controls and heart failure patients (p = 1.0402-10). The cut-off point is 2.16 with an area under the curve of 86.4%, sensitivity 79.1%, and specificity 91%. Analysis of NLR data on heart failure with hemoglobin (p = 0.108), hematocrit (p = 0.091), and platelets (p = 0.832) showed no significant correlation, whereas showed a significant correlation with leukocytes (p = 0.017). This study shows a significant difference of NLR between control and heart failure therefore it can be used to predict the prognosis for heart failure. This study also found no significant correlation between NLR with the amount of haemoglobin, hematocrit, and platelets, while there was a correlation with leukocytes.
Effectivity of Iron Supplementation With and Without Vitamin C for Increasing Hemoglobin Levels Among Women Aged 16-21 Years Old Lauryn, Jessica; Joprang, Freggy S; Kurniadi, Angela; Leonardo, Leonardo; Rinaldi, Fransiskus Xaverius; Erlina, Erlina; Singgih, Gregiorio Gavriel
Sriwijaya Journal of Medicine Vol. 5 No. 1 (2022): Vol 5, No 1, 2022
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/SJM.v5i1.125

Abstract

Anemia can be caused by a decrease in hemoglobin (Hb) levels, chronic disease, severe bleeding, nutritional deficiency, and infectious diseases. Iron deficiency is the most common cause of anemia (50%). Vitamin C has an important role in increasing absorption of iron in the body which can indirectly affect the increase in Hb formation. This study was conducted to determine whether iron and vitamin C supplementation affect the changes of Hb levels in women. This study was done by quasi experimental with single blind pretest posttest control group and with a stratified random sampling technique. Respondents were female students in Faculty of Medicine UNIKA Atma Jaya. The total number of sample was 58 which was categorized into two groups. The first group was given iron and vitamin C supplementation. The second was only given iron supplementation. There were 16 respondents (27,6%) aged 16-18 and 42 respondents (72,4%) aged 19-21. The average change in Hb level before and after intervention in group 1 was 1,934 g/dL, and P = 0,000 (P <0,05), the average change in Hb level before and after intervention in group 2 was 1,086 g/dL, and P = 0,000 (P <0,05). The difference of change in Hb levels in groups 1 and 2 had an average of 0,848 g/dL, and P = 0,005 (P <0,05). For conclusion, Iron and vitamin C supplementation has a greater impact on the changes of Hb levels compared to iron supplementation only.
Co-Authors Erlina Erlina Joprang, Freggy S Kurniadi, Angela Lauryn, Jessica Leonardo Leonardo Ridjab, Denio Adrianus Rinaldi, Fransiskus Xaverius Stefanus Lembar, Stefanus